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Author = Carroll, Douglas;
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Displaying Results 1 - 10 of 10 on page 1 of 1
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Caregiving for children with developmental disabilities is associated with a poor antibody response to influenza vaccination
(2009)
Gallagher, Stephen; Phillips, Anna C.; Drayson, Mark T.; Carroll, Douglas
Caregiving for children with developmental disabilities is associated with a poor antibody response to influenza vaccination
(2009)
Gallagher, Stephen; Phillips, Anna C.; Drayson, Mark T.; Carroll, Douglas
Abstract:
Objective: Older spousal caregivers of dementia patients have been found to show a relatively poor antibody response to medical vaccination. The present case control study compared the antibody responses to vaccination of younger parental caregivers of children with developmental disabilities and parents of typically developing children. Methods: At baseline assessment, 32 parents of children with developmental disabilities and 29 parents of typically developing children completed standard measures of perceived stress and child problem behaviours. They also provided a blood sample and were then vaccinated with the thymus-dependent trivalent influenza vaccine. Further blood samples were taken at 1- and 6-month follow-ups. Results: Relative to parents of typically developing children (mean titre = 458, SD = 155.7 at 1-month and mean titre = 265, SD = 483.0 at 6-month followup) caregivers (mean titre = 219, SD = 528.4 at 1-month and 86, SD = 55.0 at 6- month) mounted a poorer antibody ...
http://hdl.handle.net/10344/3072
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Caregiving is associated with low secretion rates of immunoglobulin A in saliva
(2008)
Gallagher, Stephen; Phillips, Anna C.; Evans, Phil; Der, Geoff; Hunt, Kate; Carroll, Do...
Caregiving is associated with low secretion rates of immunoglobulin A in saliva
(2008)
Gallagher, Stephen; Phillips, Anna C.; Evans, Phil; Der, Geoff; Hunt, Kate; Carroll, Douglas
Abstract:
Although the chronic stress of caring for a sick/disabled relative has been associated with poorer immunity using a range of outcomes, its impact on secretory immunoglobulin A (S-IgA) in saliva has yet to be examined. Three hypotheses were tested in analyses of data from a large community sample: first, caregivers would have lower S-IgA secretion rates than non-caregivers; second, the impact of caregiving on S-IgA would be particularly apparent in older participants; third, for caregivers, caregiving burden would be negatively associated with S-IgA. The sample comprised three distinct age cohorts, one young (N = 623), one middle aged (N = 639), and the other elderly (N = 582). Participants were classified as caregivers if they regularly cared for somebody other than routine childcare. Caregiving strain was measured and a caregiving burden index was then derived as the composite of the number of people being cared for, the type of care provided, and the residential status of the pers...
http://hdl.handle.net/10344/3076
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Parental caregivers of children with developmental disabilities mount a poor antibody response to pneumococcal vaccination.
(2009)
Gallagher, Stephen; Phillips, Anna C.; Drayson, Mark T.; Carroll, Douglas
Parental caregivers of children with developmental disabilities mount a poor antibody response to pneumococcal vaccination.
(2009)
Gallagher, Stephen; Phillips, Anna C.; Drayson, Mark T.; Carroll, Douglas
Abstract:
In older populations, caregiving for a spouse with dementia has been associated with a poor antibody response to vaccination. The present study examined whether younger caregivers, specifically the parents of children with developmental disabilities, would also show a diminished antibody response to vaccination. At baseline assessment, 30 parents of children with developmental disabilities and 29 parents of typically developing children completed standard measures of depression, perceived stress, social support, caregiver burden, and child problem behaviours. They also provided a blood sample and were then vaccinated with a pneumococcal polysaccharide vaccine. Further blood samples were taken at 1- and 6-month follow-ups. Caregivers mounted a poorer antibody response to vaccination than control parents at both follow-ups. This effect withstood adjustment for a number of possible confounders and appeared to be, at least in part, mediated by child problem behaviours. The negative impa...
http://hdl.handle.net/10344/4372
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Parental stress is associated with poor sleep quality in parents caring for children with developmental disabilities
(2009)
Gallagher, Stephen; Phillips, Anna C.; Carroll, Douglas
Parental stress is associated with poor sleep quality in parents caring for children with developmental disabilities
(2009)
Gallagher, Stephen; Phillips, Anna C.; Carroll, Douglas
Abstract:
Objective This study examined the psychosocial predictors of poor sleep quality in parents caring for children with developmental disabilities. Methods Sixty-seven parents of children with developmental disabilities and 42 parents of typically developing children completed the Pittsburgh Sleep Quality Index, and measures of parental stress, child problem behaviors, and social support. Results Parents of children with developmental disabilities reported poorer sleep quality. Further, the majority of these parents met the established ‘poor sleepers’ criterion. The strongest predictor of poor sleep quality was parental stress. This finding withstood adjustment for a number of potential confounders. Conclusions Parental stress is associated with poor sleep quality in parents of children with developmental disabilities. The monitoring and management of sleep issues in these parental caregivers should be a priority for health professionals.
http://hdl.handle.net/10344/586
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Predictors of psychological morbidity in parents of children with intellectual disabilities
(2008)
Gallagher, Stephen; Phillips, Anna C.; Oliver, Christopher; Carroll, Douglas
Predictors of psychological morbidity in parents of children with intellectual disabilities
(2008)
Gallagher, Stephen; Phillips, Anna C.; Oliver, Christopher; Carroll, Douglas
Abstract:
This study examined predictors of excess psychological morbidity in parents of children with intellectual disabilities.
ACCEPTED
peer-reviewed
http://hdl.handle.net/10344/4371
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Preliminary evidence that morning vaccination is associated with an enhanced antibody response in men
(2008)
Phillips, Anna C.; Gallagher, Stephen; Carroll, Douglas; Drayson, Mark T.
Preliminary evidence that morning vaccination is associated with an enhanced antibody response in men
(2008)
Phillips, Anna C.; Gallagher, Stephen; Carroll, Douglas; Drayson, Mark T.
Abstract:
Variation in response to vaccination, particularly in vulnerable groups, provides a strong rationale for developing vaccine adjuvants. If there were consistent diurnal variation in immune response this could inform a simple intervention for enhancing vaccine efficacy. Data from two studies are presented examining morning versus afternoon vaccine administration; in the first, hepatitis A vaccine was administered to young adults, and in the second, influenza vaccine to older community-based adults. Men, but not women, vaccinated in the morning mounted a better peak antibody response to both hepatitis A and the A/Panama influenza strain. These results indicate that it would be worthwhile testing this effect in a large randomised control trial with vaccination during time periods representing the extremes of hormonal and cytokine diurnal rhythms.
http://hdl.handle.net/10344/3073
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Psychosocial factors are associated with the antibody response to both thymus-dependent and thymus-independent vaccines
(2008)
Gallagher, Stephen; Phillips, Anna C.; Ferraro, Alastair J.; Drayson, Mark T.; Carroll,...
Psychosocial factors are associated with the antibody response to both thymus-dependent and thymus-independent vaccines
(2008)
Gallagher, Stephen; Phillips, Anna C.; Ferraro, Alastair J.; Drayson, Mark T.; Carroll, Douglas
Abstract:
The present study examined the association between psychological stress, social support and antibody response to both thymus-dependent and thymus-independent vaccinations. Stressful life events in the previous year and customary social support were measured by standard questionnaires at baseline in 75 (41 females) healthy students. Antibody status was assessed at baseline, 4 and 18 weeks following vaccination with formaldehyde inactivated hepatitis A virus and pneumococcal polysaccharides, which induce thymus-dependent and -independent antibody responses respectively. Controlling for baseline antibody status, life event stress was negatively associated with antibody response to the hepatitis A vaccine at the 18-week follow-up; participants reporting a greater number of stressful life events had a poorer antibody response. There was no relationship between psychological stress and antibody response to pneumococcal vaccination. Social support was not associated with the antibody respo...
http://hdl.handle.net/10344/3078
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Social support is positively associated with the immunoglobulin M response to vaccination with pneumococcal polysaccharides
(2008)
Gallagher, Stephen; Phillips, Anna C.; Ferraro, Alastair J.; Drayson, Mark T.; Carroll,...
Social support is positively associated with the immunoglobulin M response to vaccination with pneumococcal polysaccharides
(2008)
Gallagher, Stephen; Phillips, Anna C.; Ferraro, Alastair J.; Drayson, Mark T.; Carroll, Douglas
Abstract:
Evidence shows that psychosocial factors are associated with immunoglobulin G response to medical vaccinations. As yet, there are no reports of whether the earlier immunoglobulin M response is similarly susceptible. This study examined the association between psychological stress, social support and the immunoglobulin M response to vaccination with pneumococcal capsular polysaccharides. Stressful life events in the previous year and customary social support were measured by standard questionnaires at baseline in 74 healthy students (41 females). The response to five common pneumococcal serotypes was assessed at baseline and five-days following vaccination. Social support, particularly tangible social support, was positively associated with the antibody response to two of five serotypes, after controlling for baseline titre. These associations survived adjustment for demographics and health behaviours. There was no association between life events stress and immunoglobulin M response....
http://hdl.handle.net/10344/3075
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Social support, social intimacy, and cardiovascular reactions to acute psychological stress
(2009)
Phillips, Anna C.; Gallagher, Stephen; Carroll, Douglas
Social support, social intimacy, and cardiovascular reactions to acute psychological stress
(2009)
Phillips, Anna C.; Gallagher, Stephen; Carroll, Douglas
Abstract:
Background: Exaggerated cardiovascular reactions to psychological stress are considered a risk factor for cardiovascular morbidity. Social support may reduce such risk by attenuating cardiovascular reactivity to stress. Purpose: To examine the effects of three independent social support variables and their interaction on cardiovascular reactivity to acute stress. The variables were stranger or friend presence; active supportive or passive presence, and male or female presence. Methods: Cardiovascular reactions to mental arithmetic stress were measured in 112 healthy young women tested in one of eight distinct independent conditions: active supportive male friend; active supportive female friend, passive male friend; passive female friend; active supportive male stranger; active supportive female stranger, passive male stranger; and passive female stranger. Results: Support from a friend rather than a stranger was associated with attenuated blood pressure reactivity, but only when th...
http://hdl.handle.net/10344/3074
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The association between spirituality and depression in parents caring for children with developmental disabilities: social support and/or last resort
(2015)
Gallagher, Stephen; Phillips, Anna C.; Lee, Helen; Carroll, Douglas
The association between spirituality and depression in parents caring for children with developmental disabilities: social support and/or last resort
(2015)
Gallagher, Stephen; Phillips, Anna C.; Lee, Helen; Carroll, Douglas
Abstract:
Associations between spirituality and depression were examined in parents of children with developmental disabilities using both quantitative and qualitative methodology. Spirituality was positively associated with depression, whereas social support was negatively related; parents with higher spiritual beliefs and lower levels of support had higher depression scores. Themes emerging from interviews were spiritual/religious coping as a way of dealing with difficulty, as a last resort, and as a form of release from their situation. Associations between spirituality and depression in these parents are more complex than previously thought.
ACCEPTED
peer-reviewed
http://hdl.handle.net/10344/4349
Displaying Results 1 - 10 of 10 on page 1 of 1
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