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Author = Ferraro, Alastair J.;
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Displaying Results 1 - 2 of 2 on page 1 of 1
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Psychosocial factors are associated with the antibody response to both thymus-dependent and thymus-independent vaccines
(2008)
Gallagher, Stephen; Phillips, Anna C.; Ferraro, Alastair J.; Drayson, Mark T.; Carroll,...
Psychosocial factors are associated with the antibody response to both thymus-dependent and thymus-independent vaccines
(2008)
Gallagher, Stephen; Phillips, Anna C.; Ferraro, Alastair J.; Drayson, Mark T.; Carroll, Douglas
Abstract:
The present study examined the association between psychological stress, social support and antibody response to both thymus-dependent and thymus-independent vaccinations. Stressful life events in the previous year and customary social support were measured by standard questionnaires at baseline in 75 (41 females) healthy students. Antibody status was assessed at baseline, 4 and 18 weeks following vaccination with formaldehyde inactivated hepatitis A virus and pneumococcal polysaccharides, which induce thymus-dependent and -independent antibody responses respectively. Controlling for baseline antibody status, life event stress was negatively associated with antibody response to the hepatitis A vaccine at the 18-week follow-up; participants reporting a greater number of stressful life events had a poorer antibody response. There was no relationship between psychological stress and antibody response to pneumococcal vaccination. Social support was not associated with the antibody respo...
http://hdl.handle.net/10344/3078
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Social support is positively associated with the immunoglobulin M response to vaccination with pneumococcal polysaccharides
(2008)
Gallagher, Stephen; Phillips, Anna C.; Ferraro, Alastair J.; Drayson, Mark T.; Carroll,...
Social support is positively associated with the immunoglobulin M response to vaccination with pneumococcal polysaccharides
(2008)
Gallagher, Stephen; Phillips, Anna C.; Ferraro, Alastair J.; Drayson, Mark T.; Carroll, Douglas
Abstract:
Evidence shows that psychosocial factors are associated with immunoglobulin G response to medical vaccinations. As yet, there are no reports of whether the earlier immunoglobulin M response is similarly susceptible. This study examined the association between psychological stress, social support and the immunoglobulin M response to vaccination with pneumococcal capsular polysaccharides. Stressful life events in the previous year and customary social support were measured by standard questionnaires at baseline in 74 healthy students (41 females). The response to five common pneumococcal serotypes was assessed at baseline and five-days following vaccination. Social support, particularly tangible social support, was positively associated with the antibody response to two of five serotypes, after controlling for baseline titre. These associations survived adjustment for demographics and health behaviours. There was no association between life events stress and immunoglobulin M response....
http://hdl.handle.net/10344/3075
Displaying Results 1 - 2 of 2 on page 1 of 1
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