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Limited By:	Author = Kelly, Daniel;

Displaying Results 101 - 124 of 124 on page 5 of 5

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Sommera cusucoana, a new species of Rubiaceae from Honduras (2015)

KELLY, DANIEL

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Stresses in peripheral arteries following stent placement: a finite element analysis (2009)

PRENDERGAST, PATRICK; KELLY, DANIEL; LALLY, CAITRIONA

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Substrate stiffness and oxygen availability as regulators of mesenchymal stem cell differentiation within a mechanically loaded bone chamber. (2014)

KELLY, DANIEL

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Tensile and compressive properties of fresh human carotid atherosclerotic plaques. (2009)

KELLY, DANIEL; LALLY, CAITRIONA

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Testing indicators of biodiversity for plantation forests (2013)

MITCHELL, FRASER; KELLY, DANIEL

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The Composition of Engineered Cartilage at the Time of Implantation Determines the Likelihood of Regenerating Tissue with a Normal Collagen Architecture. (2013)

KELLY, DANIEL

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The effect of concentration, cooling rate and cell seeding density on the initial mechanical properties of agarose hydrogels. (2009)

Buckley, Conor; Robinson, Anthony; Kelly, Daniel

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The effect of cyclic hydrostatic pressure on the functional development of cartilaginous tissues engineered using bone marrow derived mesenchymal stem cells (2011)

KELLY, DANIEL; BUCKLEY, CONOR

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The effect of prosthesis design on vibration of the reconstructed ossicular chain: a comparative finite element analysis of four prostheses (2003)

KELLY, DANIEL; PRENDERGAST, PATRICK JOHN

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The identification of articular cartilage and growth plate extracellular matrix-specific proteins supportive of either osteogenesis or stable chondrogenesis of stem cells (2020)

Kelly, Daniel

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The impacts of traditional and novel herbicide application methods on target plants, non-target plants and production in intensive grasslands (2013)

POWER, EILEEN; STOUT, JANE; KELLY, DANIEL

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The influence of construct scale on the composition and functional properties of cartilaginous tissues engineered using bone marrow-derived mesenchymal stem cells. (2012)

Kelly, Daniel; Buckley, Conor

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The influence of expansion rates on mandibular distraction osteogenesis: a computational analysis (2007)

KELLY, DANIEL

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The influence of plaque composition on underlying arterial wall stress during stent expansion: the case for lesion-specific stents (2009)

KELLY, DANIEL; LALLY, CAITRIONA

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The influence of ventilation tube design on the magnitude of stress imposed at the implant/tympanic membrane interface (2008)

KELLY, DANIEL; PRENDERGAST, PATRICK JOHN

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The pericellular environment regulates cytoskeletal development and the differentiation of mesenchymal stem cells and determines their response to hydrostatic pressure. (2013)

KELLY, DANIEL

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The role of mechanical signals in regulating chondrogenesis and osteogenesis of mesenchymal stem cells (2010)

KELLY, DANIEL

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Three-Dimensional Bioprinting of Polycaprolactone Reinforced Gene Activated Bioinks for Bone Tissue Engineering (2017)

KELLY, DANIEL; DALY, ANDREW; NELSON SATHY, BINULAL; Cunniffe, Gr?inne M.; Gonzalez-Fern...

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Tissue differentiation and bone regeneration in an osteotomized mandible: a computational analysis of the latency period (2008)

KELLY, DANIEL; PRENDERGAST, PATRICK JOHN

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Tissue engineering scaled-up, anatomically shaped osteochondral constructs for joint resurfacing (2015)

KELLY, DANIEL; BUCKLEY, CONOR; VINARDELL, TATIANA

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Tissue engineering whole bones through endochondral ossification: Regenerating the distal phalanx (2015)

BUCKLEY, CONOR; KELLY, DANIEL

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Tissue-specific extracellular matrix scaffolds for the regeneration of spatially complex musculoskeletal tissues (2019)

Kelly, Daniel; Dunne, Aisling; Cunniffe, Gr?inne M.; D?az-Payno, Pedro J.; Sheehy, Eamo...

Tissue-specific extracellular matrix scaffolds for the regeneration of spatially complex musculoskeletal tissues (2019)

Kelly, Daniel; Dunne, Aisling; Cunniffe, Gr?inne M.; D?az-Payno, Pedro J.; Sheehy, Eamon J.; Critchley, Susan E.; Almeida, Henrique V.; Pitacco, Pierluca; Carroll, Simon F.; Mahon, Olwyn R.; Levingstone, Tanya J.; Moran, Conor J.; Brady, Robert T.; O'Brien, Fergal J.; Brama, Pieter A.J.

Abstract:

Biological scaffolds generated from tissue-derived extracellular matrix (ECM) are commonly used clinically for soft tissue regeneration. Such biomaterials can enhance tissue-specific differentiation of adult stem cells, suggesting that structuring different ECMs into multi-layered scaffolds can form the basis of new strategies for regenerating damaged interfacial tissues such as the osteochondral unit. In this study, mass spectrometry is used to demonstrate that growth plate (GP) and articular cartilage (AC) ECMs contain a unique array of regulatory proteins that may be particularly suited to bone and cartilage repair respectively. Applying a novel iterative freeze-drying method, porous bi-phasic scaffolds composed of GP ECM overlaid by AC ECM are fabricated, which are capable of spatially directing stem cell differentiation in vitro, promoting the development of graded tissues transitioning from calcified cartilage to hyaline-like cartilage. Evaluating repair 12-months post-implant...