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Author = Sinnott, Sarah-Jo;
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Displaying Results 1 - 10 of 10 on page 1 of 1
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Cost minimization analysis of intravenous or subcutaneous trastuzumab treatment in patients with HER2-positive breast cancer in Ireland
(2019)
O'Brien, Gary L.; O'Mahony, Cian; Cooke, Katie; Kinneally, Ada; Sinnott, Sara...
Cost minimization analysis of intravenous or subcutaneous trastuzumab treatment in patients with HER2-positive breast cancer in Ireland
(2019)
O'Brien, Gary L.; O'Mahony, Cian; Cooke, Katie; Kinneally, Ada; Sinnott, Sarah-Jo; Walshe, Valerie; Mulcahy, Mark; Byrne, Stephen
Abstract:
Background: Two large acute Irish University teaching hospitals changed the manner in which they treated human epidermal growth factor receptor (HER)2-positive breast cancer patients by implementing the administration of trastuzumab via the subcutaneous (SC) route into their clinical practice. The study objective is to compare the trastuzumab SC and trastuzuamb intravenous (IV) treatment pathways in both hospitals and assess which route is more cost-effective and time saving in relation to active health care professional (HCP) time. Materials and Methods: A prospective observational study in the form of cost minimization analysis constituted the study design. Active HCP time for trastuzumab SC- and IV-related tasks were recorded. Staff costs were calculated using fully loaded salary costs. Loss of productivity costs for patients were calculated using the human capital method. Results: On average, the total HCP time saved per trastuzumab SC treatment cycle relative to trastuzumab IV ...
http://hdl.handle.net/10468/7660
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Estimating the prevalence and incidence of type 2 diabetes using population level pharmacy claims data: a cross-sectional study
(2017)
Sinnott, Sarah-Jo; McHugh, Sheena M.; Whelton, Helen; Layte, Richard; Barron, Steve J.;...
Estimating the prevalence and incidence of type 2 diabetes using population level pharmacy claims data: a cross-sectional study
(2017)
Sinnott, Sarah-Jo; McHugh, Sheena M.; Whelton, Helen; Layte, Richard; Barron, Steve J.; Kearney, Patricia M.
Abstract:
Objective: To estimate the prevalence and incidence of type 2 diabetes using a national pharmacy claims database. Research design and methods We used data from the Health Service Executive-Primary Care Reimbursement Service database in Ireland for this cross-sectional study. Prevalent cases of type 2 diabetes were individuals using an oral hypoglycemic agent, irrespective of insulin use, in 2012. Incident cases were individuals using an oral hypoglycemic agent in 2012 who had not used one in the past. Population level estimates were calculated and stratified by age and sex. Results: In 2012, there were 114 957 prevalent cases of type 2 diabetes giving a population prevalence of 2.51% (95% CI 2.49% to 2.52%). Among adults (≥15yrs), this was 3.16% (95% CI 3.15% to 3.18%). The highest prevalence was in those aged 70+ years (12.1%). 21 574 people developed type 2 diabetes in 2012 giving an overall incidence of 0.48% (95% CI 0.48% to 0.49%). In adults, this was 0.60% (95% CI 0.60% to 0.6...
http://hdl.handle.net/10468/3476
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Is 50 cent the price of the optimal copayment? - a qualitative study of patient opinions and attitudes in response to a 50 cent charge on prescription drugs in a publicly funded health system in Ireland
(2013)
Sinnott, Sarah-Jo; Guinane, Marie; Whelton, Helen; Byrne, Stephen
Is 50 cent the price of the optimal copayment? - a qualitative study of patient opinions and attitudes in response to a 50 cent charge on prescription drugs in a publicly funded health system in Ireland
(2013)
Sinnott, Sarah-Jo; Guinane, Marie; Whelton, Helen; Byrne, Stephen
Abstract:
Background: A 50 cent prescription levy was introduced in 2010 on the General Medical Services (GMS) scheme (Irish public health insurance). This study sought to examine patient attitudes and opinions surrounding the 50 cent copayment. Given the small momentary value of the prescription fee, these results are of interest to policymakers internationally who wish to reduce copayments rather than abolish them. Methods: A qualitative research design was used; semi structured interviews were carried out. Twenty four GMS eligible participants were interviewed in 23 interviews. Fifteen females and 9 males took part. Ages varied from 31- >70 years. Patients were invited to be interviewed in both independent and chain community pharmacies in three types of setting; 1) a socially deprived urban area, 2) a suburban affluent area and 3) a rural area. The Framework method was used for data management and analysis using QSR International’s NVivo 9.2 qualitative data analysis software. The “Fra...
http://hdl.handle.net/10468/2398
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National Variation in Caesarean Section Rates: A Cross Sectional Study in Ireland
(2016)
Sinnott, Sarah-Jo; Brick, Aoife; Layte, Richard; Cunningham, Nathan; Turner, Michael
National Variation in Caesarean Section Rates: A Cross Sectional Study in Ireland
(2016)
Sinnott, Sarah-Jo; Brick, Aoife; Layte, Richard; Cunningham, Nathan; Turner, Michael
Abstract:
Objective: Internationally, caesarean section (CS) rates are rising. However, mean rates of CS across providers obscure extremes of CS provision. We aimed to quantify variation between all maternity units in Ireland. Methods: Two national databases, the National Perinatal Reporting System and the Hospital Inpatient Enquiry Scheme, were used to analyse data for all women delivering singleton births weighing ≥500g. We used multilevel models to examine variation between hospitals in Ireland for elective and emergency CS, adjusted for individual level sociodemographic, clinical and organisational variables. Analyses were subsequently stratified for nullipara and multipara with and without prior CS. Results: The national CS rate was 25.6% (range 18.2% ─ 35.1%). This was highest in multipara with prior CS at 86.1% (range 6.9% ─ 100%). The proportion of variation in CS that was attributable to the hospital of birth was 11.1% (95% CI, 6.0 ─ 19.4) for elective CS and 2.9% (95% CI, 1.4 ─ 5.6)...
http://hdl.handle.net/10197/7672
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National Variation in Caesarean Section Rates: A Cross Sectional Study in Ireland.
(2016)
Sinnott, Sarah-Jo; Brick, Aoife; Layte, Richard; Cunningham, Nathan; Turner, Michael J
National Variation in Caesarean Section Rates: A Cross Sectional Study in Ireland.
(2016)
Sinnott, Sarah-Jo; Brick, Aoife; Layte, Richard; Cunningham, Nathan; Turner, Michael J
Abstract:
Internationally, caesarean section (CS) rates are rising. However, mean rates of CS across providers obscure extremes of CS provision. We aimed to quantify variation between all maternity units in Ireland.
http://hdl.handle.net/10147/622952
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Oral cancer incidence and survival rates in the Republic of Ireland, 1994-2009
(2016)
Ali, Hala; Sinnott, Sarah-Jo; Corcoran, Paul; Deady, Sandra E.; Sharp, Linda; Kabir, Zu...
Oral cancer incidence and survival rates in the Republic of Ireland, 1994-2009
(2016)
Ali, Hala; Sinnott, Sarah-Jo; Corcoran, Paul; Deady, Sandra E.; Sharp, Linda; Kabir, Zubair
Abstract:
Background: Oral cancer is a significant public health problem world-wide and exerts high economic, social, psychological, and physical burdens on patients, their families, and on their primary care providers. We set out to describe the changing trends in incidence and survival rates of oral cancer in Ireland between 1994 and 2009. Methods: National data on incident oral cancers [ICD 10 codes C01-C06] were obtained from the National Cancer Registry Ireland from 1994 to 2009. We estimated annual percentage change (APC) in oral cancer incidence during 1994–2009 using joinpoint regression software (version 4.2.0.2). The lifetime risk of oral cancer to age 79 was estimated using Irish incidence and population data from 2007 to 2009. Survival rates were also examined using Kaplan-Meier curves and Cox proportional hazard models to explore the influence of several demographic/lifestyle covariates with follow-up to end 2012. Results: Data were obtained on 2,147 oral cancer incident cases. M...
http://hdl.handle.net/10468/3423
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Oral cancer incidence and survival rates in the Republic of Ireland, 1994-2009.
(2016)
Ali, Hala; Sinnott, Sarah-Jo; Corcoran, Paul; Deady, Sandra; Sharp, Linda; Kabir, Zubair
Oral cancer incidence and survival rates in the Republic of Ireland, 1994-2009.
(2016)
Ali, Hala; Sinnott, Sarah-Jo; Corcoran, Paul; Deady, Sandra; Sharp, Linda; Kabir, Zubair
Abstract:
Oral cancer is a significant public health problem world-wide and exerts high economic, social, psychological, and physical burdens on patients, their families, and on their primary care providers. We set out to describe the changing trends in incidence and survival rates of oral cancer in Ireland between 1994 and 2009. Methods: National data on incident oral cancers [ICD 10 codes C01-C06] were obtained from the National Cancer Registry Ireland from 1994 to 2009. We estimated annual percentage change (APC) in oral cancer incidence during 1994–2009 using joinpoint regression software (version 4.2.0.2). The lifetime risk of oral cancer to age 79 was estimated using Irish incidence and population data from 2007 to 2009. Survival rates were also examined using Kaplan-Meier curves and Cox proportional hazard models to explore the influence of several demographic/lifestyle covariates with follow-up to end 2012.
Oral cancer is a significant public health problem world-wide and exerts h...
http://hdl.handle.net/10147/621147
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Out of pocket or out of control: A qualitative analysis of healthcare professional stakeholder involvement in pharmaceutical policy change in Ireland
(2020)
O'Brien, Gary L.; Sinnott, Sarah-Jo; O'Flynn, Bridget; Walshe, Valerie; Mulca...
Out of pocket or out of control: A qualitative analysis of healthcare professional stakeholder involvement in pharmaceutical policy change in Ireland
(2020)
O'Brien, Gary L.; Sinnott, Sarah-Jo; O'Flynn, Bridget; Walshe, Valerie; Mulcahy, Mark; Byrne, Stephen
Abstract:
Background: Mandatory co-payments attached to prescription medicines on the Irish public health insurance [General Medical Services (GMS)] scheme have undergone multiple iterations since their introduction in October 2010. To date, whilst patients’ opinions on said co-payments have been evaluated, the perspectives of community pharmacists and general practitioners (GPs) have not. Objective: To explore the involvement and perceptions of community pharmacists and GPs on this pharmaceutical policy change. Methods: A qualitative study using purposive sampling alongside snowballing recruitment was used. Nineteen interviews were conducted in a Southern region of Ireland. Data were analysed using the Framework Approach. Results: Three major themes emerged: 1) the withered tax-collecting pharmacist; 2) concerns and prescribing patterns of physicians; and 3) the co-payment system – impact and sustainability. Both community pharmacists and GPs accepted the theoretical concept of a co-payment ...
http://hdl.handle.net/10468/9724
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Pharmacoepidemiology resources in Ireland-an introduction to pharmacy claims data.
(2017)
Sinnott, Sarah-Jo; Bennett, Kathleen; Cahir, Caitriona
Pharmacoepidemiology resources in Ireland-an introduction to pharmacy claims data.
(2017)
Sinnott, Sarah-Jo; Bennett, Kathleen; Cahir, Caitriona
Abstract:
Administrative health data, such as pharmacy claims data, present a valuable resource for conducting pharmacoepidemiological and health services research. Often, data are available for whole populations allowing population level analyses. Moreover, their routine collection ensures that the data reflect health care utilisation in the real-world setting compared to data collected in clinical trials.
The Irish Health Service Executive-Primary Care Reimbursement Service (HSE-PCRS) community pharmacy claims database is described. The availability of demographic variables and drug-related information is discussed. The strengths and limitations associated using this database for conducting research are presented, in particular, internal and external validity. Examples of recently conducted research using the HSE-PCRS pharmacy claims database are used to illustrate the breadth of its use.
The HSE-PCRS national pharmacy claims database is a large, high-quality, valid and accurate dat...
http://hdl.handle.net/10147/622522
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The effect of copayments for prescriptions on adherence to prescription medicines in publicly insured populations; A systematic review and meta-analysis
(2013)
Sinnott, Sarah-Jo; Buckley, Claire M.; O'Riordan, David; Bradley, Colin P.; Whelto...
The effect of copayments for prescriptions on adherence to prescription medicines in publicly insured populations; A systematic review and meta-analysis
(2013)
Sinnott, Sarah-Jo; Buckley, Claire M.; O'Riordan, David; Bradley, Colin P.; Whelton, Helen
Abstract:
Introduction: Copayments are intended to decrease third party expenditure on pharmaceuticals, particularly those regarded as less essential. However, copayments are associated with decreased use of all medicines. Publicly insured populations encompass some vulnerable patient groups such as older individuals and low income groups, who may be especially susceptible to medication non-adherence when required to pay. Non-adherence has potential consequences of increased morbidity and costs elsewhere in the system. Objective: To quantify the risk of non-adherence to prescribed medicines in publicly insured populations exposed to copayments. Methods: The population of interest consisted of cohorts who received public health insurance. The intervention was the introduction of, or an increase, in copayment. The outcome was non-adherence to medications, evaluated using objective measures. Eight electronic databases and the grey literature were systematically searched for relevant articles, al...
http://hdl.handle.net/10468/2376
Displaying Results 1 - 10 of 10 on page 1 of 1
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Lenus (3)
University College Cork (6)
University College Dublin (1)
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