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Limited By:	Author = Tilson, Lesley;

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Cost-effectiveness of population-based screening for colorectal cancer: a comparison of guaiac-based faecal occult blood testing, faecal immunochemical testing and flexible sigmoidoscopy. (2012)

Sharp, Linda; Tilson, Lesley; Whyte, Sophie; O'Ceilleachair, Alan; Walsh, Cathal D...

Sharp, Linda; Tilson, Lesley; Whyte, Sophie; O'Ceilleachair, Alan; Walsh, Cathal Dominic; Usher, Cara; Tappenden, Paul; Chilcott, James; Staines, Anthony; Barry, Michael; Comber, Harry

Abstract:

Several colorectal cancer-screening tests are available, but it is uncertain which provides the best balance of risks and benefits within a screening programme. We evaluated cost-effectiveness of a population-based screening programme in Ireland based on (i) biennial guaiac-based faecal occult blood testing (gFOBT) at ages 55-74, with reflex faecal immunochemical testing (FIT); (ii) biennial FIT at ages 55-74; and (iii) once-only flexible sigmoidoscopy (FSIG) at age 60.
PUBLISHED
peer-reviewed

http://hdl.handle.net/10344/4932

Marked Mark

Pharmacoeconomic evaluation in Ireland: A review of the process (2010)

Tilson, Lesley; O’Leary, Aisling; Usher, Cara; Barry, Michael

Pharmacoeconomic evaluation in Ireland: A review of the process (2010)

Tilson, Lesley; O’Leary, Aisling; Usher, Cara; Barry, Michael

Abstract:

The aim of this review is to describe the pharmacoeconomic assessment process in Ireland and to provide examples of recent appraisals and the subsequent impact on pricing and reimbursement decisions. Method: The pharmacoeconomic appraisals conducted by the National Centre for Pharmacoeconomics (NCPE) between September 2006 and February 2009 were reviewed. The NCPE recommendations and subsequent reimbursement decisions by the Health Service Executive (HSE) were recorded. Recommendations made by the NCPE were compared with those of UK agencies. The duration of the NCPE pharmacoeconomic process and the time from marketing authorisation to reimbursement was estimated. The budget impact assessments from the pharmaceutical companies were reviewed and compared for consistency. Results: The NCPE conducted twelve single technology appraisals during the study period. Eight of the medicines assessed were either recommended as a cost-effective use of resources or recommended with certain re...

http://hdl.handle.net/10147/302606

Marked Mark

Proton pump inhibitors: potential cost reductions by applying prescribing guidelines. (2012)

Cahir, Caitriona; Fahey, Tom; Tilson, Lesley; Teljeur, Conor; Bennett, Kathleen

Proton pump inhibitors: potential cost reductions by applying prescribing guidelines. (2012)

Cahir, Caitriona; Fahey, Tom; Tilson, Lesley; Teljeur, Conor; Bennett, Kathleen

Abstract:

This article is also available from <a href="http://www.biomedcentral.com">www.biomedcentral.com</a>
BACKGROUND: There are concerns that proton pump inhibitors (PPI) are being over prescribed in both primary and secondary care. This study aims to establish potential cost savings in a community drug scheme for a one year period according to published clinical and cost-effective guidelines for PPI prescribing. METHODS: Retrospective population-based cohort study in the Republic of Ireland using the Health Services Executive (HSE) Primary Care Reimbursement Services (PCRS) pharmacy claims database. The HSE-PCRS scheme is means tested and provides free health care including medications to approximately 30% of the Irish population. Prescription items are WHO ATC coded and details of every drug dispensed and claimants' demographic data are available. Potential cost savings (net ingredient cost) were estimated ac...

https://epubs.rcsi.ie/gpart/32

Marked Mark

Reply: cost-effectiveness of population-based screening for colorectal cancer. (2013)

Sharp, Linda; Walsh, Cathal Dominic; Whyte, Sophie; Tilson, Lesley; O'Ceilleachair...

Reply: cost-effectiveness of population-based screening for colorectal cancer. (2013)

Sharp, Linda; Walsh, Cathal Dominic; Whyte, Sophie; Tilson, Lesley; O'Ceilleachair, Alan; Usher, Cara; Tappenden, Paul; Chilcott, James; Staines, Anthony; Barry, Michael; Comber, Harry

Abstract:

In his letter, Dr O’Mahony (2012) makes two main points. The first of these relates to the number of alternatives explored during our assessment of colorectal cancer screening in Ireland (Sharp et al, 2012), and the second relates to the terminology used in the paper. Our paper reports findings from a health technology assessment (HTA) of colorectal cancer screening; the full report has been published (Health Information and Quality Authority, 2009a). The purpose of HTA is to inform decision makers about the relative efficacy and costs of possible health-care interventions in order that coherent policy decisions can be taken. In the case of our work, the question of interest was whether population screening for colorectal cancer in Ireland would be effective and cost effective.
PUBLISHED
peer-reviewed

http://hdl.handle.net/10344/4929

Marked Mark

Using resource modelling to inform decision making and service planning: the case of colorectal cancer screening in Ireland (2013)

Sharp, Linda; Tilson, Lesley; Whyte, Sophie; Ó Ceilleachair, Alan; Walsh, Cathal Domini...

Using resource modelling to inform decision making and service planning: the case of colorectal cancer screening in Ireland (2013)

Sharp, Linda; Tilson, Lesley; Whyte, Sophie; Ó Ceilleachair, Alan; Walsh, Cathal Dominic; Usher, Cara; Tappenden, Paul; Chilcott, James; Staines, Anthony; Barry, Michael; Comber, Harry

Abstract:

Background: Organised colorectal cancer screening is likely to be cost-effective, but cost-effectiveness results alone may not help policy makers to make decisions about programme feasibility or service providers to plan programme delivery. For these purposes, estimates of the impact on the health services of actually introducing screening in the target population would be helpful. However, these types of analyses are rarely reported. As an illustration of such an approach, we estimated annual health service resource requirements and health outcomes over the first decade of a population-based colorectal cancer screening programme in Ireland. Methods: A Markov state-transition model of colorectal neoplasia natural history was used. Three core screening scenarios were considered: (a) flexible sigmoidoscopy (FSIG) once at age 60, (b) biennial guaiac-based faecal occult blood tests (gFOBT) at 55–74 years, and (c) biennial faecal immunochemical tests (FIT) at 55–74 years. Three alternati...

http://hdl.handle.net/10344/4928

Displaying Results 1 - 5 of 5 on page 1 of 1