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Institution = NUI Maynooth;
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Displaying Results 2626 - 2650 of 2835 on page 106 of 114
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The Virtual Lab Approach to Pharmacokinetics: Design Principles and Concepts.
(2006)
Huisinga, Wilhelm; Telgmann, Regina ; Wulkow, Michael
The Virtual Lab Approach to Pharmacokinetics: Design Principles and Concepts.
(2006)
Huisinga, Wilhelm; Telgmann, Regina ; Wulkow, Michael
Abstract:
Modeling and simulation in pharmacokinetics has has turned into the focus of pharmaceutical companies, driven by the emerging consensus that in silico predictions combined with in vitro data have the potential of significantly increasing insight into pharmacokinetic processes. To adequately support in silico methodology, software tools need to be user-friendly and, at the same time, flexible. In brief, the software has to allow the realization of modeling ideas that are beyond current knowledge – in the form of a virtual lab. We present and discuss the necessary design principles and concepts. These have been implemented in the software package MEDICI-PK to demonstrate its feasibility and advantages.
http://eprints.nuim.ie/1739/
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The Way We Once Were: the Nigerian writer, Flora Nwapa
(2005)
Fallon, Helen
The Way We Once Were: the Nigerian writer, Flora Nwapa
(2005)
Fallon, Helen
Abstract:
This review article explores the life and writing of Nigerian novelist Flora Nwapa
http://eprints.nuim.ie/952/
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The Weakness and Strength of Christianity
(2002)
Henry, Martin
The Weakness and Strength of Christianity
(2002)
Henry, Martin
Abstract:
That divine and human wisdom do not necessarily coincide, is an ancient idea, whose validity, in the Christian world at any rate, may not depend solely on the rhetorical talent of its first proponent, St Paul. Similarly, the reversal of apparently self-evident ideas â for example, that strength is superior to weakness, or that fame is preferable to obscurity â has not just been part of the stock-in-trade of Christian apologetics over the centuries, but seems to be woven into the fundamental experience of humanity. âGreatnessâ comes eventually to be revealed as megalomania, and âfameâ, as the Chinese sage, Chuang Tzu, has it, âis the beginning of disgraceâ.
http://eprints.nuim.ie/636/
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The Welfare Implications of Growth Regressions
(2005)
O'Neill, Donal
The Welfare Implications of Growth Regressions
(2005)
O'Neill, Donal
Abstract:
Regressions relating the growth rate in income to initial income have been the soruce of much recent debate in growth economics. recent reserch has empasised the importance of allowing for non-linearities in these models when explaining the evolution of income over time. In this paper we argue these extended growth regressions are also useful in facilitating welfae comparisions across income distributions, in a way that is not possible using alternative measures of convergence. To do this we exploit the similarities between the income convergence literature and work on tax progressivity in the public finance literature. We illustrate our approch using both regional dta across the United States, Japan and Europe and conutrwide comparisions.
http://eprints.nuim.ie/218/
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The Western Front
(2005)
O'Farrell, Anthony G.
The Western Front
(2005)
O'Farrell, Anthony G.
Abstract:
This is an expanded version of a talk given (under the title Ars Longa (Im Westen nichts Neues) at the symposium to honour T.T. West, held in Trinity College on 19-20 December, 2005. It describes some problems posed by Trevor West, arising from his work, or related to it.
http://eprints.nuim.ie/1796/
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The Wild Irish Girl and the "dalai lama of little Thibet": the long encounter between Ireland and Asian Buddhism
(2011)
Cox, Laurence; Griffin, Maria
The Wild Irish Girl and the "dalai lama of little Thibet": the long encounter between Ireland and Asian Buddhism
(2011)
Cox, Laurence; Griffin, Maria
Abstract:
Ireland lies on the margins of the Buddhist world, far from its homeland in northern India and Nepal and the traditionally Buddhist parts of Asia. It is also in various ways "peripheral" to core capitalist societies, and Irish encounters with Buddhism are structured by both facts. Buddhism, for its part, has been a central feature of major Eurasian societies for over two millennia. During this period, Irish people and Asian Buddhists have repeatedly encountered or heard about each other, in ways structured by many different kinds of global relations – from the Roman Empire and the medieval church via capitalist exploration, imperial expansion and finally contemporary capitalism. These different relationships have conditioned different kinds of encounters and outcomes. At the same time, as succeeding tides of empire, trade and knowledge have crossed Eurasia, each tide has left its traces. In 1859, Fermanagh-born James Tennent's best-selling History of Ceylon could devo...
http://eprints.nuim.ie/2514/
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The writing skills course as an introduction to critical practice for larger business undergraduate classes
(2011)
Cullen, John G.
The writing skills course as an introduction to critical practice for larger business undergraduate classes
(2011)
Cullen, John G.
Abstract:
Calls for greater levels of critical thought in business and management education increased in the wake of the global financial crisis. Many business educators articulated a need to develop students who engage with theory at the deepest level in order to cultivate more socially engaged managers and management thinkers. These calls surfaced at a time when or organisations voiced concerns about the quality of the basic literacy and numeracy skills of graduates. It is often difficult to introduce students to critical practice at the undergraduate level due to larger class sizes, with the result that deeper theoretical engagement is often postponed until postgraduate stages of business education. This paper discusses the findings from an action research project conducted on a critical writing skills project which aimed to introduce a group of 95 first-year business students to the concept of critical practice through their written assignments. The research unearthed some opportunities, ...
http://eprints.nuim.ie/2763/
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The writing skills course as an introduction to critical practice for larger business undergraduate classes
(2011)
Cullen, John G.
The writing skills course as an introduction to critical practice for larger business undergraduate classes
(2011)
Cullen, John G.
Abstract:
Calls for greater levels of critical thought in business and management education increased in the wake of the global financial crisis. Many business educators articulated a need to develop students who engage with theory at the deepest level in order to cultivate more socially engaged managers and management thinkers. These calls surfaced at a time when organisations voiced concerns about the quality of the basic literacy and numeracy skills of graduates. It is often difficult to introduce students to critical practice at the undergraduate level due to larger class sizes, with the result that deeper theoretical engagement is often postponed until postgraduate stages of business education. This paper discusses the findings from an action research project conducted on a critical writing skills project which aimed to introduce a group of 95 first-year business students to the concept of critical practice through their written assignments. The research unearthed some opportunities, cha...
http://eprints.nuim.ie/2975/
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The yeast prion protein Ure2: Structure, function and folding
(2006)
Lian, Hui-Yong; Jiang, Yi; Zhang, Hong; Jones, Gary; Perrett, Sarah
The yeast prion protein Ure2: Structure, function and folding
(2006)
Lian, Hui-Yong; Jiang, Yi; Zhang, Hong; Jones, Gary; Perrett, Sarah
Abstract:
The Saccharomyces cerevisiae protein Ure2 functions as a regulator of nitrogen metabolism and as a glutathione-dependent peroxidase. Ure2 also has the characteristics of a prion, in that it can undergo a heritable conformational change to an aggregated state; the prion form of Ure2 loses the regulatory function, but the enzymatic function appears to be maintained. A number of factors are found to affect the prion properties of Ure2, including mutation and expression levels of molecular chaperones, and the effect of these factors on structure and stability are being investigated. The relationship between structure, function and folding for the yeast prion Ure2 are discussed.
http://eprints.nuim.ie/922/
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The Zero Temperature Phase Diagram of the Kitaev Model
(2009)
Nash, Charles; O'Connor, Denjoe
The Zero Temperature Phase Diagram of the Kitaev Model
(2009)
Nash, Charles; O'Connor, Denjoe
Abstract:
We show that the zero temperature phase diagram of the vortex free sector of the Kitaev model is in one to one correspondence with that of the classical dimer model on the corresponding lattice. We find that the model generically has three distinct phases. On a honeycomb lattice with a 3 × 3 fundamental domain all three phases are accessible. As the couplings are varied there are two distinct transitions. The new transition is one to a gapped phase that opens up in the interior of the B phase of the Kitaev model.
http://eprints.nuim.ie/1566/
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Theodore Crowley ofm 1910-1990
(2004)
McEvoy, Prof. James
Theodore Crowley ofm 1910-1990
(2004)
McEvoy, Prof. James
Abstract:
Included in text.
http://eprints.nuim.ie/455/
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Theoretical and Experimental Analysis of Chain Transfer Agents Behaviors in Photopolymer Material
(2011)
Guo, J. ; Gleeson, M. R. ; Sheridan, J. T.
Theoretical and Experimental Analysis of Chain Transfer Agents Behaviors in Photopolymer Material
(2011)
Guo, J. ; Gleeson, M. R. ; Sheridan, J. T.
Abstract:
The Non-local Photo-Polymerization Driven Diffusion (NPDD) model indicates how a material’s performance might be improved, and provides a tool for quantitive comparison of different material compositions and to predict their fundamental limits. In order to reduce the non-locality of polymer chain growth (i.e the non-local response parameter, σ) and to improve the spatial frequency response of a photopolymer material, we introduce the chain transfer agent (CTA). In the literature, extensive studies have been carried out on the improvements of the non-local response modifying by the CTA, sodium formate, in the polyvinyl alcohol-acrylamide (PVA/AA) material. In this article, i) based on the chemical reactions of CTA, we extended the CTA model in the literature; ii) we compare two different CTA materials, sodium formate and 1-mercapto-2-propanol without cross-linker in order to obtain the experimental confirmation of the reduction in the average polymer molecular weight is provided usin...
http://eprints.nuim.ie/3589/
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Theoretical and experimental investigation of phase gratings
(1998)
Lanigan, Dr. William; Colgan, Dr. Ruth; Murphy, Dr. Anthony J.; Withington, Dr. Stafford
Theoretical and experimental investigation of phase gratings
(1998)
Lanigan, Dr. William; Colgan, Dr. Ruth; Murphy, Dr. Anthony J.; Withington, Dr. Stafford
Abstract:
We present the results of experimental measurements of a Dammann grating designed to produce a 5 x 5 pattern of beam images at 100GHz
http://eprints.nuim.ie/62/
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Theorising "Youth"
(2009)
Devlin, Maurice
Theorising "Youth"
(2009)
Devlin, Maurice
Abstract:
Theory is something that is often not highly valued by youth workers and others who work with young people. "I'm not a great one for theory. I prefer to get on with doing the job," is a not uncommon opinion. Such a view is based on a misunderstanding of the nature of theory and of the relationship between theory and practice. Specifically, it reflects the misguided notion that theory is necessarily both abstract and abstruce, something "academic" and impractical. But in fact, as Kurt Lewin once wrote, "there is nothing as practical as a good theory" (Lewin, 1952:346). Theory is essentially concerned with explanation and understanding of why things are the way they are; of why things work the way they do. It is therefore utterly indispensable to good practice, whether the practice in question is car mechanics, brain surgery or youth work.
http://eprints.nuim.ie/3526/
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Theory of Topological Edges and Domain Walls
(2009)
Bais, F.A.; Slingerland, J.K.; Haaker, S.M.
Theory of Topological Edges and Domain Walls
(2009)
Bais, F.A.; Slingerland, J.K.; Haaker, S.M.
Abstract:
We investigate domain walls between topologically ordered phases in two spatial dimensions. We present a method which allows for the determination of the superselection sectors of excitations of such walls and which leads to a unified description of the kinematics of a wall and the two phases to either side of it. This incorporates a description of scattering processes at domain walls which can be applied to questions of transport through walls. In addition to the general formalism, we give representative examples including domain walls between the Abelian and non-Abelian topological phases of Kitaev’s honeycomb lattice model in a magnetic field, as well as recently proposed domain walls between spin polarized and unpolarized non-Abelian fractional quantum Hall states at different filling fractions.
http://eprints.nuim.ie/2064/
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Therapy of Renewal: The Third European Ecumenical Assembly
(2007)
Leahy, Brendan
Therapy of Renewal: The Third European Ecumenical Assembly
(2007)
Leahy, Brendan
Abstract:
This article reflects from within a Catholic perspective on some of the pointers for renewal that emerged in the light of the Third European Ecumenical Assembly's Final Message and comments made during the Assembly itself
http://eprints.nuim.ie/785/
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Thermal instability with the effect of cosmic-ray diffusion
(2009)
Shadmehri, Mohsen
Thermal instability with the effect of cosmic-ray diffusion
(2009)
Shadmehri, Mohsen
Abstract:
We study dynamical effects of cosmics rays (CRs) on the thermal instability in the linear regime. CRs and the thermal plasma are treated as two different interacting fluids, in which CRs can diffuse along the magnetic field lines. We show that growth rate of the magnetothermal condensation mode is reduced because of the existence of CRs and this stabilizing effect depends on the diffusion coefficient and the ratio of the CRs pressure to gas pressure. Thus, a slower rate of structure formation via thermal instability is predicted when CRs are considered.
http://eprints.nuim.ie/2790/
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Thinking about maps
(2009)
Kitchin, Rob; Perkins, Chris; Dodge, Martin
Thinking about maps
(2009)
Kitchin, Rob; Perkins, Chris; Dodge, Martin
Abstract:
Given the long history of map-making and its scientific and scholarly traditions one might expect the study of cartography and mapping theory to be relatively moribund pursuits with long established and static ways of thinking about and creating maps. This, however, could not be further from the truth. As historians of cartography have amply demonstrated, cartographic theory and praxis has varied enormously across time and space, and especially in recent years. As conceptions and philosophies of space and scientific endeavour have shifted so has how people come to know and map the world. Philosophical thought concerning the nature of maps is of importance because it dictates how we think about, produce and use maps; it shapes our assumptions about how we can know and measure the world, how maps work, their techniques, aesthetics, ethics, ideology, what they tell us about the world, the work they do in the world, and our capacity as humans to engage in mapping. Mapping is epistemolog...
http://eprints.nuim.ie/2875/
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This Irish Fiction of Emily Lawless: a narrative analysis
(2009)
Prunty, Brendan
This Irish Fiction of Emily Lawless: a narrative analysis
(2009)
Prunty, Brendan
Abstract:
If the measure of a writer‟s relevance is the extent to which he or she registers the discursive range of the period in which they write and the extent to which subsequent generations can recover that discursive energy from his or her work, then Emily Lawless should require no justification for inclusion in a tradition of significant Irish literary voices. The fictional work, in particular, of this writer facilitates access to an expanse of issues which constituted a major part of late nineteenth-century political, social and cultural debate in both Ireland and Britain. Most notably, the dissident alternative aspiration which she voiced to an increasingly monologic Irish nationalism renders a study of her work indispensable to a thorough and meaningful appraisal of that period. The methodology employed in this study is, through a close textual reading of the four major novels which have a direct bearing on the national project, Hurrish, With Essex in Ireland, Grania and Maelcho, to ...
http://eprints.nuim.ie/2267/
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This is My Country: the Kenyan author, Ngugi wa Thiong’o
(2006)
Fallon, Helen
This is My Country: the Kenyan author, Ngugi wa Thiong’o
(2006)
Fallon, Helen
Abstract:
This review article explores the life and writing of Kenyan novelist Ngugi wa Thiong'o
http://eprints.nuim.ie/961/
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Thomas Messingham (c.1575-1638?) and the seventeenth-century Church
(2000)
O'Connor, Thomas
Thomas Messingham (c.1575-1638?) and the seventeenth-century Church
(2000)
O'Connor, Thomas
Abstract:
The early seventeenth century was a formative period in Irish history. With the extension of Stuart power following the defeat, and later, the flight of the Earls, the country entered into a new phase of political, social and religious change. The extension of English law, the policy of plantation, the state's harassement of Catholics and the increasing centralisation of political authority served to isolate the Catholic community from the sources of power and patronage. While most Irish Catholics accepted James 1 as their lawful king, they insisted that their political loyalty to him could be reconciled with their religious loyalty to the Pope. The King and his government, however, would prove immune to their reasoning. Nor was this the only problem facing Irish Catholics. Prolonged war had shattered the church's structures and Reformation had taken away its material sustenance. In the relatively peaceful 1610s and 1620s a new generation of Catholic bishops and clergy set...
http://eprints.nuim.ie/768/
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Three dimensional digital holographic profiling of micro-fibers
(2009)
Kempkes, Michel; Darakis, Emmanouil; Khanam, Taslima; Rajendran, Arvind; Kariwala, Vina...
Three dimensional digital holographic profiling of micro-fibers
(2009)
Kempkes, Michel; Darakis, Emmanouil; Khanam, Taslima; Rajendran, Arvind; Kariwala, Vinay; Mazzotti, Marco; Naughton, Thomas J.; Asundi, Anand K.
Abstract:
A method to measure the size, orientation, and location of opaque micro-fibers using digital holography is presented. The method involves the recording of a digital hologram followed by reconstruction at different depths. A novel combination of automated image analysis and statistical techniques, applied on the intensity of reconstructed digital holograms is used to accurately determine the characteristics of the microfibers. The performance of the proposed method is verified with a single fiber of known length and orientation. The potential of the method for measurement of fiber length is further demonstrated through its application to a suspension of fibers in a liquid medium.
http://eprints.nuim.ie/2719/
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Three Essays on International Financial Market Linkages
(2009)
Syngelaki, Eirini
Three Essays on International Financial Market Linkages
(2009)
Syngelaki, Eirini
Abstract:
This thesis investigates three cutting edge issues in empirical finance. The first, examined in Chapter 2, is an investigation of the hypothesis that macroeconomic uncertainty is a significant risk factor in explaining deviations from the uncovered interest parity (UIP) condition (or time-varying risk premium) using data from the G7 countries. To analyze the relationship between the risk premium and macroeconomic risk factors, we employ VAR-GARCH-in-mean models. The results show that the currency risk premium may be due to macroeconomic volatility. The second issue (Chapter 3) concerns the causal linkages between monetary and financial market returns of the New Member States (NMS) with the euro zone following the introduction of the euro. To measure monetary convergence we employ UIP deviations and stock market integration is proxied by the differential of the risk-adjusted returns of the NMS countries versus a euro zone stock index. We look for a causal relationship between excess ...
http://eprints.nuim.ie/2014/
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Three-dimensional image sensing, encryption, compression, and transmission using digital holography
(2004)
Naughton, Thomas J.; Tajahuerce, Enrique; McDonald, John B.; Javidi, Bahram
Three-dimensional image sensing, encryption, compression, and transmission using digital holography
(2004)
Naughton, Thomas J.; Tajahuerce, Enrique; McDonald, John B.; Javidi, Bahram
Abstract:
We present the results of applying data compression techniques to encrypted three-dimensional (3D) objects. The objects are captured using phase-shift digital holography and encrypted using a random phase mask in the Fresnel domain. Both the amplitude and the phase of our 3D objects are encrypted using this technique. The advantage of a digital representation of the optical wavefronts is that they can be processed and transmitted using conventional means. Arbitrary views of the 3D objects are decrypted and reconstructed using digital propagation. Compression is applied to the encrypted digital holograms prior to transmission. Degradation due to lossy quantization compression is measured in the reconstruction domain. Finally, we use a speedup metric to validate that our compression techniques are viable for time-critical 3D imaging applications. Our techniques are suitable for a range of secure 3D object storage and transmission applications.
http://eprints.nuim.ie/398/
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Timbral attributes for objective quality assessment of the Irish Tin Whistle
(2004)
Timoney, Joseph; MacManus, Lorcan; Lysaght, Thomas; Schwarzbacher, A.
Timbral attributes for objective quality assessment of the Irish Tin Whistle
(2004)
Timoney, Joseph; MacManus, Lorcan; Lysaght, Thomas; Schwarzbacher, A.
Abstract:
In this paper we extract various timbral attributes for a variety of Irish tin whistles, and use these attributes to form an objective quality assessment of the instruments. This assessment is compared with the subjective experiences of a number of professional musicians. The timbral attributes are drawn from those developed in the Timbre Model
http://eprints.nuim.ie/421/
Displaying Results 2626 - 2650 of 2835 on page 106 of 114
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