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'Doing' health policy analysis: methodological and conceptual reflections and challenges. (2008)

Walt, Gill; Shiffman, Jeremy; Schneider, Helen; Murray, Susan F; Brugha, Ruairi F; Gils...

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'It's risky to walk in the city with syringes': understanding access to HIV/AIDS services for injecting drug users in the former Soviet Union countries of Ukraine and Kyrgyzstan. (2011)

Spicer, Neil; Bogdan, Daryna; Brugha, Ruairi; Harmer, Andrew; Murzalieva, Gulgun; Semig...

Mark

'Reduce Resistance' An Antibiotic stewardship program to change prescribing practices in a Public Dental Service (2015)

McCafferty, Rosarii

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'Reference rot': A developing problem in Emergency Medicine Australasia. (2015)

O'Connor, Colm; O'Connor, Alan

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'Smart' non-viral delivery systems for targeted delivery of RNAi to the lungs. (2013)

Ramsey, Joanne M; Hibbitts, Alan; Barlow, James; Sivadas, Neeraj; Cryan, Sally-Ann

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'Suing the Pope' and Scandalising the People: Irish Attitudes to Sexual Abuse by Clergy Pre- and Post-Screening of a Critical Documentary (2009)

Breen, Michael J; McGee, Hannah; O'Boyle, Ciaran; Goode, Helen; Devereux, Eoin

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‘Emigration is a matter of self-preservation. The working conditions . . . are killing us slowly’: qualitative insights into health professional emigration from Ireland (2015)

Humphries, Niamh; McAleese, Sara; Matthews, Anne; Brugha, Ruairi

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‘Potentially inappropriate or specifically appropriate?’ Qualitative evaluation of general practitioners views on prescribing, polypharmacy and potentially inappropriate prescribing in older people. (2016)

Clyne, Barbara; Cooper, Janine A; Hughes, Carmel M; Fahey, Tom; Smith, Susan M; OPTI-SC...

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‘You do not cross them’: Hierarchy and emotion in doctors' narratives of power relations in specialist training (2017)

Crowe, Sophie; Clarke, Nicholas; Brugha, Ruairi F

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"An unspoken world of unspoken things": a study identifying and exploring core beliefs underlying self-stigma among people living with HIV and AIDS in Ireland. (2015)

France, Nadine Ferris; Mcdonald, Steve H; Conroy, Ronán; Byrne, Elaine; Mallouris, Chri...

Mark

"I found myself staying" - A case study of the job embeddedness and retention of qualified health workers in rural and remote areas of Uganda (2015)

Maniple, Everd B

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"I won't be staying here for long": a qualitative study on the retention of migrant nurses in Ireland. (2009)

Humphries, Niamh; Brugha, Ruairi; McGee, Hannah

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"Pee-in-a-Pot": acceptability and uptake of on-site chlamydia screening in a student population in the Republic of Ireland (2010)

Vaughan, Deirdre; O'Connell, Emer; Cormican, Martin; Brugha, Ruairi; Faherty, Cole...

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"Preconditioning" with latrepirdine, an adenosine 5'-monophosphate-activated protein kinase activator, delays amyotrophic lateral sclerosis progression in SOD1(G93A) mice. (2015)

Coughlan, Karen S; Mitchem, Mollie R; Hogg, Marion C; Prehn, Jochen HM

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"The problem is ours, it is not CRAIDS' ". Evaluating sustainability of Community Based Organisations for HIV/AIDS in a rural district in Zambia. (2012)

Walsh, Aisling; Mulambia, Chishimba; Brugha, Ruairi; Hanefeld, Johanna

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"The way the country has been carved up by researchers": ethics and power in north-south public health research. (2016)

Walsh, Aisling M; Brugha, Ruairi F; Byrne, Elaine

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"TORNADO" - Theranostic One-Step RNA Detector; microfluidic disc for the direct detection of microRNA-134 in plasma and cerebrospinal fluid. (2017)

McArdle, Hazel; Jimenez-Mateos, Eva M; Raoof, Rana; Carthy, Eadaoin; Boyle, David; ElNa...

"TORNADO" - Theranostic One-Step RNA Detector; microfluidic disc for the direct detection of microRNA-134 in plasma and cerebrospinal fluid. (2017)

McArdle, Hazel; Jimenez-Mateos, Eva M; Raoof, Rana; Carthy, Eadaoin; Boyle, David; ElNaggar, Hany; Delanty, Norman; Hamer, Hajo; Dogan, Muejgdan; Huchtemann, Tessa; Kӧrtvelyessy, Peter; Rosenow, Felix; Forster, Robert J; Henshall, David C; Spain, Elaine

Abstract:

<p>The original article is available at www.nature.com</p>
<p>Diagnosis of seizure disorders such as epilepsy currently relies on clinical examination and electroencephalogram recordings and is associated with substantial mis-diagnosis. The miRNA, miR-134 (MIR134 in humans), has been found to be elevated in brain tissue after experimental status epilepticus and in human epilepsy cells and their detection in biofluids may serve as unique biomarkers. miRNAs from unprocessed human plasma and human cerebrospinal fluid samples were used in a novel electrochemical detection based on electrocatalytic platinum nanoparticles inside a centrifugal microfluidic device where the sandwich assay is formed using an event triggered release system, suitable for the rapid point-of-care detection of low abundance biomarkers of disease. The device has the advantage of controlling the rotation speed of the centrifugal device to pump nanoliter volumes of fluid at a set time and manip...