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Subject = Adverse Drug Event;
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Displaying Results 1 - 3 of 3 on page 1 of 1
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Explicit criteria as clinical tools to minimize inappropriate medication use and its consequences
(2019)
Curtin, Denis; Gallagher, Paul F.; O'Mahony, Denis
Explicit criteria as clinical tools to minimize inappropriate medication use and its consequences
(2019)
Curtin, Denis; Gallagher, Paul F.; O'Mahony, Denis
Abstract:
Polypharmacy and prescribing of potentially inappropriate medications (PIMs) are the key elements of inappropriate medication use (IMU) in older multimorbid people. IMU is associated with a range of negative healthcare consequences including adverse drug events and unplanned hospitalizations. Furthermore, prescribing guidelines are commonly derived from randomized controlled clinical trials which have specifically excluded older adults with multimorbidity. Consequently, indiscriminate application of single disease pharmacotherapy guidelines to older multimorbid patients can lead to increased risk of drug?drug interactions, drug?disease interactions and poor drug adherence. Both polypharmacy and PIMs are highly prevalent in older people and strategies to improve the quality and safety of prescribing, largely through avoidance of IMU, are needed. In the last 30?years, numerous explicit PIM criteria-based tools have been developed to assist physicians with medication management in clin...
http://hdl.handle.net/10468/9161
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Medication reviews by a clinical pharmacist at an Irish university teaching hospital
(2017)
Kearney, Alan; Halleran, Ciaran; Walsh, Elaine K.; Byrne, Derina; Haugh, Jennifer; Sahm...
Medication reviews by a clinical pharmacist at an Irish university teaching hospital
(2017)
Kearney, Alan; Halleran, Ciaran; Walsh, Elaine K.; Byrne, Derina; Haugh, Jennifer; Sahm, Laura J.
Abstract:
Purpose: Pharmacist-led medication reviews in hospitals have shown improvement in patient outcomes. The aim of this study is to describe the prevalence and nature of pharmacist interventions (PIs) following a medication review in an Irish teaching hospital. Methods: PIs were recorded over a six-month period in 2015. PIs were assessed by a panel of healthcare professionals (n = 5) to estimate the potential of adverse drug events (ADEs). Descriptive statistics were used for the variables and the chi square test for independence was used to analyse for any association between the variables. Results: Of the 1216 patients (55.8% female; median age 68 years (interquartile range 24 years)) who received a medication review, 313 interventions were identified in 213 patients. 412 medicines were associated with PIs, of which drugs for obstructive airway disease (n = 82), analgesics (n = 56), and antibacterial products for systemic use (n = 50) were the most prevalent. A statistically significa...
http://hdl.handle.net/10468/5389
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Predicting adverse health outcomes in older community-dwelling adults: a prospective cohort study
(2016)
Wallace, Emma
Predicting adverse health outcomes in older community-dwelling adults: a prospective cohort study
(2016)
Wallace, Emma
Abstract:
<p><strong>Background</strong></p> <p>This thesis aimed to investigate if adverse health outcomes in older community-dwelling people can be predicted, through the application of measures of prescribing, multimorbidity and emergency admission risk models. There were five objectives: 1) to determine if there is a longitudinal association between potentially inappropriate prescribing (PIP) and future adverse drug events (ADEs), reduced health related quality of life (HRQOL) and increased use of Accident & Emergency (A&E) and emergency admissions; 2) to assess the performance of different measures of multimorbidity and vulnerability in predicting emergency hospital attendance and functional decline; 3) to conduct a systematic review of emergency admission risk prediction models developed for use in community-dwelling adults; 4) to systematically review and meta-analyse the validation studies of the Probability of repeated admissions (Pra) risk model...
https://epubs.rcsi.ie/phdtheses/175
Displaying Results 1 - 3 of 3 on page 1 of 1
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Institution
Royal College of Surgeons i... (1)
University College Cork (2)
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Doctoral thesis (1)
Journal article (2)
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Peer-reviewed (2)
Non-peer-reviewed (1)
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2019 (1)
2017 (1)
2016 (1)
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