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Limited By:	Subject = Cardiovascular disease (CVD);

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Displaying Results 1 - 5 of 5 on page 1 of 1

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Association of objectively measured physical activity with vascular endothelial function in male adolescents (2015)

Sheridan, Sinead; Moyna, Niall

Association of objectively measured physical activity with vascular endothelial function in male adolescents (2015)

Sheridan, Sinead; Moyna, Niall

Abstract:

Purpose: Cardiovascular disease (CVD) begins in childhood primarily due to exposure to lifestyle-mediated risk factors such as inactivity and low cardiorespiratory fitness (CRF). Endothelial dysfunction is one of the earliest events in the development of CVD. Self-reported light intensity physical activity (LIPA) is positively associated with endothelial function (EF) in adolescents. The purpose of this study was to examine the relation between objectively measured physical activity (PA) and EF in healthy male adolescents. Methods: Low (n=8, VO2max = 40.4 ± 2.3 mL.kg1.min-1), moderate CRF (n=12,VO2max = 54.6 ± 3.9 mL.kg1.min-1) and high CRF (n=15, VO2max = 63.7 ± 4.0 mL.kg1.min-1) healthy males (mean age 15.77 ± 0.4; yr) participated in the study. High-resolution ultrasonography was used to assess endothelial dependent (EDD) in response to brachial artery flow mediated dilation. Participants wore a tri-axial ActivPAL accelerometer for 6 days. Total time spent in sitting, st...

http://doras.dcu.ie/20673/

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Barriers and motivators in engaging with technology-enabled cardiac rehabilitation: a patient and health professional perspective. (2016)

Walsh, Deirdre; Woods, Catherine; Moran, Kieran; McCaffrey, Noel; Cornelissen, Véroniqu...

Barriers and motivators in engaging with technology-enabled cardiac rehabilitation: a patient and health professional perspective. (2016)

Walsh, Deirdre; Woods, Catherine; Moran, Kieran; McCaffrey, Noel; Cornelissen, Véronique; Buys, Roselien; Cornelis, Nils; Newton, Helen; Gallagher, Anne; Casserly, Ivan; McAdam, Brendan

Abstract:

Background Cardiovascular disease (CVD) is the leading cause of premature death and disability in Europe. Effective cardiac rehabilitation (CR) can improve mortality and morbidity rates, yet uptake of community-based CR is low (Department of Health and Children, 2010). PATHway (Physical Activity Towards Health) is a technology enabled behaviour change intervention designed to enable patients to self-manage their health. Aims From a patient’s perspective, this study aims to determine the key personal, social and physical factors that inhibit or promote a patient’s capacity to engage with a technology enabled CR programme. From a healthcare professional’s perspective, this study aims to explore a) opinions and preferences for the most appropriate content and most viable approach for delivery of the PATHway intervention, b) strategies for recruitment and retention of study participants, c) treatment adherence, and d) strategies to overcome barriers to the acceptability of the intervent...

http://doras.dcu.ie/21153/

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Immunomodulatory activity of 5 kDa permeate fractions of casein hydrolysates generated using a range of enzymes in Jurkat T cells and RAW264.7 macrophages (2019)

O'Sullivan, Siobhan M.; O'Callaghan, Yvonne C.; O'Keeffe, Martina B.; Fi...

Immunomodulatory activity of 5 kDa permeate fractions of casein hydrolysates generated using a range of enzymes in Jurkat T cells and RAW264.7 macrophages (2019)

O'Sullivan, Siobhan M.; O'Callaghan, Yvonne C.; O'Keeffe, Martina B.; Fitzgerald, Richard J.; O'Brien, Nora M.

Abstract:

The in vitro bioactivity of 5 kDa ultrafiltration permeate fractions of casein hydrolysates produced using different enzymes were compared. Reverse phase ultra-performance liquid chromatography and gel permeation chromatography showed that the permeates had different physicochemical properties (molecular mass and degree of hydrolysis). The Flavourzyme® permeate had the highest activity in the 2,2’-azinobis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) assay. Cellular antioxidant and immunomodulatory assays showed that none of the permeates exhibited in vitro antioxidant activity, while all permeates significantly (P < 0.05) decreased interleukin-6 (IL-6) production in ConA-stimulated Jurkat T cells at 0.50% (w/v) and LPS-stimulated RAW264.7 cells at 0.05 and 0.50% (w/v). Three permeates, obtained using Flavourzyme®, Flavorpro Whey and trypsin, also significantly (P < 0.05) decreased IL-1β production at 0.05% (w/v) in RAW264.7 cells. Western blot analysis showed that all perm...

http://hdl.handle.net/10344/7670

Marked Mark

Technology use among patients with cardiovascular disease: an assessment of patient need for a technology enabled behavioural change intervention. (2015)

Woods, Catherine; Walsh, Deirdre; Furlong, Bróna; Moran, Kieran; Monaghan, David; McCaf...

Technology use among patients with cardiovascular disease: an assessment of patient need for a technology enabled behavioural change intervention. (2015)

Woods, Catherine; Walsh, Deirdre; Furlong, Bróna; Moran, Kieran; Monaghan, David; McCaffrey, Noel; O'Connor, Noel E.; Buys, Roselien; Cornelissen, Véronique

Abstract:

Effective Cardiac Rehabilitation (CR) can significantly improve mortality and morbidity rates in relation to cardiovascular disease; however, uptake of traditional community-based long-term is very low. PATHway (Physical Activity Towards Health) will provide individualized rehabilitation programs, through an internet-enabled sensor-based home exercise platform that allows remote participation. The purpose of this study was to assess the level of interest and use of technology by individuals living with CVD in order to inform the design of a technology-enabled CR programme. Method: A technology usage questionnaire based on a previous study investigating the role of technology and mHealth in a CVD population was used (Dale et al., 2014) to ascertain the current level of technology use. All patients attending the Phase Four community cardiac rehabilitation HeartSmart programme (MedEx) were recruited (N=67; 66.2 years, SD= 8.55, Males =76.1%, Females=20.9%). Results: Technology usage ...

http://doras.dcu.ie/20660/

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The differential impact of subjective and objective aspects of social engagement on cardiovascular risk factors (2010)

WHELAN, BRENDAN JAMES; TIMONEN, VIRPI; KAMIYA, YUMIKO; KENNY, ROSE ANNE

The differential impact of subjective and objective aspects of social engagement on cardiovascular risk factors (2010)

WHELAN, BRENDAN JAMES; TIMONEN, VIRPI; KAMIYA, YUMIKO; KENNY, ROSE ANNE

Abstract:

Background: This article provides new insights into the impact of social engagement on CVD risk factors in older adults. We hypothesized that objective (social participation, social ties and marital status) and subjective (emotional support) aspects of social engagement are independently associated with objective measures of cardiovascular risk. Methods: Data from the English Longitudinal Study on Ageing (ELSA) were analyzed. The effects of social participation, social ties, marital status, and emotional support on hypertension, obesity, high sensitivity C-reactive protein, and fibrinogen were estimated by logistic regression controlling for age, sex, education, physical function, depression, cardiovascular disease, other chronic diseases, physical activity, and smoking. Results: Social participation is a consistent predictor of low risk for four risk factors, even after controlling for a wide range of covariates. Being married is associated with lower risk for hypertension. Social ...

http://hdl.handle.net/2262/41183

Displaying Results 1 - 5 of 5 on page 1 of 1