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Displaying Results 1 - 25 of 71 on page 1 of 3
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?She stimulates us to supply what is not there?: Expanding Jane Austen?s World Through Fandom
(2018)
MADDEN, AINE MARIA
?She stimulates us to supply what is not there?: Expanding Jane Austen?s World Through Fandom
(2018)
MADDEN, AINE MARIA
Abstract:
This thesis aims to explore Jane Austen?s lively afterlife in popular culture through an exploration of fanfiction inspired by her most popular novel, Pride and Prejudice (1813). The thesis combines analysis of online fanfiction with criticism of professionally published (profic) texts and film and digital adaptations as a way of contextualising Austen fandom. As a form of writing that is essentially about reading, Austen fanfiction can be interpreted as a valuable form of reader response that can illuminate the literary and cultural preoccupations of Austen?s readers, the ?Janeites?. Austen?s reception and readership have become increasingly topical subjects within Austen Studies. However, Austen-inspired fanfiction has yet to receive meaningful critical attention as studies of Austen?s readers tend to have an historical focus, concentrating on her male ?scholarly? readers from the nineteenth century rather than her predominantly female contemporary fans. The author?s place in cont...
http://hdl.handle.net/2262/84985
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'Kaleidoscopes of Changing Pictures': Representing nations in toy theatres
(2018)
Hofer-Robinson, Joanna
'Kaleidoscopes of Changing Pictures': Representing nations in toy theatres
(2018)
Hofer-Robinson, Joanna
Abstract:
Toy theatre was an adjunct trade to London theatreland in the nineteenth century. Publishers produced miniature versions of popular productions on stage in contemporary playhouses. Consequently, toy theatre has typically been studied as a unique visual record of theatrical scenery and costumes. This article aims to question these assumptions, and to argue that these toys should be critically examined as performances in their own right. In 1854 the Lord Chamberlain’s Office licensed the ‘Grand Military Spectacle’ of ‘The Battle of the Alma’ at Astley’s Amphitheatre. Both the spectacle and the humour of the drama drew on the interplay between domestic and foreign settings and stereotypes. Far from presenting simplified models of place, space, and identification, however, Astley’s used stock characters and generic tropes to play with and unsettle national identities, and to encourage the audience to question press coverage of the Crimean War. At least two toy theatre publishers adapted...
http://hdl.handle.net/10468/5548
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‘Once upon a time would not prove to be All-time or even a long time.’ From sanitary reform to cultural memory: The case of Jacob’s Island
(2020)
Hofer-Robinson, Joanna
‘Once upon a time would not prove to be All-time or even a long time.’ From sanitary reform to cultural memory: The case of Jacob’s Island
(2020)
Hofer-Robinson, Joanna
http://hdl.handle.net/10468/10144
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A vulnerability framework to protect coastal social ecological systems
(2019)
O'Higgins, Tim; O'Dwyer, Barry
A vulnerability framework to protect coastal social ecological systems
(2019)
O'Higgins, Tim; O'Dwyer, Barry
Abstract:
Due to a long and beneficial legacy, human settlement and development is particularly concentrated in coastal zones and this concentration is expected to continue and increase in the future. Coastal dwelling, however, also entails risks from both anthropogenic and natural hazards and interactions between these. A spatially explicit ecosystem services framework combined with a vulnerability framework is used to explore human relations with the coast and to assess current and future capacities to ensure benefits of coastal migration and to address the risks that these areas pose. The spatial characteristics of some fundamental benefits — transport and settlement, fisheries and waste assimilation — of coastal dwelling and their associated environmental costs are first analysed using modern and historical examples. A variety of spatial characteristics describing human use patterns are then identified. On this basis, the implications of the variety of spatial scales in benefits and costs...
http://hdl.handle.net/10468/8553
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Adaptable near and far: C. H. Hazlewood's double adaptations
(2020)
Hofer-Robinson, Joanna
Adaptable near and far: C. H. Hazlewood's double adaptations
(2020)
Hofer-Robinson, Joanna
Abstract:
Stage personnel faced complex and conflicting demands in the nineteenth century to curate and cater to appetites for theatre with perceived local relevance and increasingly mobile and diverse audiences. This article argues that the formulaic melodramas written for less reputable London theatres allowed for just such local identification as well as for coming and going, as playwrights produced dramas which simultaneously traded on their knowledge of managerial preferences and theatrical companies while retaining an inclusive ambiguity in their scripts by avoiding specific political affiliation and curating moments of metatheatrical humour that appealed to audiencesâ general knowledge of stage conventions, rather than specific local contexts or affiliations. Focusing on two very different dramatisations of Charles Readeâ s novel It Is Never Too Late to Mend, both written by C. H. Hazlewood, this article analyses how the playwright addressed the tastes and capabilities of a network ...
http://hdl.handle.net/10468/10514
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Adaptation of Reputation Management Systems to Dynamic Network Conditions in Ad Hoc Networks
(2010)
DA SILVA, LUIZ
Adaptation of Reputation Management Systems to Dynamic Network Conditions in Ad Hoc Networks
(2010)
DA SILVA, LUIZ
Abstract:
Reputation management systems have been proposed as a cooperation enforcement solution in ad hoc networks. Typically, the functions of reputation management (evaluation, detection, and reaction) are carried out homogeneously across time and space. However, the dynamic nature of ad hoc networks causes node behavior to vary both spatially and temporally due to changes in local and network-wide conditions. When reputation management functions do not adapt to such changes, their effectiveness, measured in terms of accuracy (correct identification of node behavior) and promptness (timely identification of node misbehavior), may be compromised. We propose an adaptive reputation management system that realizes that changes in node behavior may be driven by changes in network conditions and that accommodates such changes by adapting its operating parameters. We introduce a time-slotted approach to allow the evaluation function to quickly and accurately capture changes in node behavior. We s...
http://hdl.handle.net/2262/52989
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Adapting child-robot interaction to reflect age and gender
(2017)
Sandygulova, Anara
Adapting child-robot interaction to reflect age and gender
(2017)
Sandygulova, Anara
Abstract:
Research and commercial robots have infiltrated homes, hospitals and schools, becoming attractive and proving impactful for children’s healthcare, therapy, edutainment, and other applications. The focus of this thesis is to investigate a little explored issue of how children’s perception of the robot changes with age, and thus to create such a robot to adapt to these differences. In particular, this research investigates the impact of gender segregation on children’s interactions with a humanoid NAO robot. To this end, a series of experiments was conducted with children aged between 5 and 12 years old. The results suggest that children aged between 9 and 12 years old do not support gender segregation hypothesis with a gendered robot.In order to dynamically adapt to children’s age and gender, a perception module was developed using depth data and a collected depth dataset of 3D body metrics of 428 children aged between 5 and 16 years old. This module is able to successfully determine...
http://hdl.handle.net/10197/8579
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AMP-activated protein kinase (AMPK)-induced preconditioning in primary cortical neurons involves activation of MCL-1.
(2013)
Anilkumar, Ujval; Weisová, Petronela; Düssmann, Heiko; Concannon, Caoimhín G; König, Ha...
AMP-activated protein kinase (AMPK)-induced preconditioning in primary cortical neurons involves activation of MCL-1.
(2013)
Anilkumar, Ujval; Weisová, Petronela; Düssmann, Heiko; Concannon, Caoimhín G; König, Hans-Georg; Prehn, Jochen HM
Abstract:
<p>This article is also available at <a href="http://onlinelibrary.wiley.com/doi/10.1111/jnc.12108/pdf">http://onlinelibrary.wiley.com/doi/10.1111/jnc.12108/pdf</a></p>
<p>Neuronal preconditioning is a phenomenon where a previous exposure to a sub-lethal stress stimulus increases the resistance of neurons towards a second, normally lethal stress stimulus. Activation of the energy stress sensor, AMP-activated protein kinase (AMPK) has been shown to contribute to the protective effects of ischaemic and mitochondrial uncoupling-induced preconditioning in neurons, however, the molecular basis of AMPK-mediated preconditioning has been less well characterized. We investigated the effect of AMPK preconditioning using 5-aminoimidazole-4-carboxamide riboside (AICAR) in a model of NMDA-mediated excitotoxic injury in primary mouse cortical neurons. Activation of AMPK with low concentrations of AICAR (0.1 mM for 2 h) induced a transient increase in AM...
https://epubs.rcsi.ie/physiolart/39
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Barriers to the adoption of alley cropping as a climate-smart agriculture practice: lessons from maize cultivation among the maya in southern belize
(2018)
Kongsager, Rico
Barriers to the adoption of alley cropping as a climate-smart agriculture practice: lessons from maize cultivation among the maya in southern belize
(2018)
Kongsager, Rico
Abstract:
Climate-smart agriculture (CSA) is proposed as a necessity, as the agricultural sector will need to adapt to resist future climatic change, to which high emissions from the sector contribute significantly. This study, which is an exploratory case study based on qualitative interviews and field observations, investigates the barriers to making a CSA-adjustment in maize production among Maya communities in southern Belize. The adjustment is alley cropping, which is a low-input adjustment that has the potential to result in both adaptation and mitigation benefits, and furthermore, to enhance food security. The findings show that a CSA-adjustment in small-scale maize production in Maya villages in southern Belize is possible in principle, though several barriers can make the overall climate-smart objective difficult to implement in practice. The barriers are of a proximate and indirect nature, exist at different spatial scales, and involve various levels of governance. The barriers are ...
http://hdl.handle.net/10379/12302
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Beneath the penumbral glow: John Banville and the cinema
(2016)
Kirwan, Mark
Beneath the penumbral glow: John Banville and the cinema
(2016)
Kirwan, Mark
Abstract:
This study focuses on the cinematic aspects of John Banville’s work, aiming to answer how the overt cinematic interest in the cinema in his later work is to be understood in the context of his writing career as a whole. His writing plays on the difficulties inherent in the relationship between appearances and reality, raising questions about how words and images, accurately or otherwise, represent the world. The thesis here is that the cinema has become a significant feature and powerful symbolic image of these preoccupations in the later period of Banville’s career, resonating with his earlier work while bringing a new frame through which to look at his novels and wider career. This cinematic interest continues the Banvillian tradition of appropriating other art forms in the construction of his novels and also is a deeply resonant form considering the predominant themes of surface, appearance and inability to penetrate reality in his work. Following this thread involves the conside...
http://hdl.handle.net/10468/4186
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Cold adaptation and replicable microbial community development during long-term low-temperature anaerobic digestion treatment of synthetic sewage
(2019)
Keating, Ciara; Hughes, D.; Mahony, D.; Cysneiros, T.; Ijaz, U. Z.; Smith, C. J.; O...
Cold adaptation and replicable microbial community development during long-term low-temperature anaerobic digestion treatment of synthetic sewage
(2019)
Keating, Ciara; Hughes, D.; Mahony, D.; Cysneiros, T.; Ijaz, U. Z.; Smith, C. J.; O'Flaherty, Vincent
Abstract:
The development and activity of a cold-adapting microbial community was monitored during low-temperature anaerobic digestion (LtAD) treatment of wastewater. Two replicate hybrid anaerobic sludge bed-fixed-film reactors treated a synthetic sewage wastewater at 12 degrees C, at organic loading rates of 0.25-1.0 kg chemical oxygen demand (COD) m(-3) d(-1), over 889 days. The inoculum was obtained from a full-scale anaerobic digestion reactor, which was operated at 37 degrees C. Both LtAD reactors readily degraded the influent with COD removal efficiencies regularly exceeding 78% for both the total and soluble COD fractions. The biomass from both reactors was sampled temporally and tested for activity against hydrolytic and methanogenic substrates at 12 degrees C and 37 degrees C. Data indicated that significantly enhanced low-temperature hydrolytic and methanogenic activity developed in both systems. For example, the hydrolysis rate constant (k) at 12 degrees C had increased 20-30-fold...
http://hdl.handle.net/10379/15361
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Conscientiousness and cardiovascular reactivity to recurrent acute psychological stress
(2019)
Sesker, Amanda
Conscientiousness and cardiovascular reactivity to recurrent acute psychological stress
(2019)
Sesker, Amanda
Abstract:
Introduction. Conscientiousness is a personality construct encompassing the trait of being careful, vigilant, dutiful, and concerned about the implications of one’s actions. It is a core trait within the five-factor personality trait model, and is known for its stability and consistency across the lifespan, as well as its predictability for health behaviour choices that affect morbidity and longevity. Research has presented robust evidence for the influence of socio-behavioural models in moderating conscientiousness and stress appraisal. However, far less scrutiny has been given in addressing whether direct psychosomatic mechanisms might not also play a significant role in moderating this relationship. The central research of this thesis will examine the systematic associations between conscientiousness and acute cardiovascular stress responsivity, and will argue for the consideration of conscientiousness in future psychosomatic models of stress. Methods. Four empirical studies wer...
http://hdl.handle.net/10379/15001
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Defining and quantifying coping strategies after stroke: a review.
(2006)
Donnellan, Claire; Hevey, David; Hickey, Anne; O'Neill, Desmond
Defining and quantifying coping strategies after stroke: a review.
(2006)
Donnellan, Claire; Hevey, David; Hickey, Anne; O'Neill, Desmond
Abstract:
The original article is copyright of the BMJ Publishing Group Ltd and is available at http://jnnp.bmj.com/cgi/content/full/77/11/1208
The coping strategies that people use after a stroke may influence recovery. Coping measures are generally used to assess the mediating behaviour between a stressor (ie, disease or condition) and the physical or psychological outcome of an individual. This review evaluates measures that quantified coping strategies in studies on psychological adaptation to stroke. The main aspects of the coping measures reviewed were (a) conceptual basis; (b) coping domains assessed; (c) coping strategies used after a stroke; and (d) psychometric properties of coping measures used in studies assessing patients with stroke. Four databases (Medline, CINAHL, PsychINFO and Cochrane Systematic Reviews) were searched to identify studies that used a coping measure in stroke. 14 studies assessed coping strategies in patients after stroke. Ten different coping measures wer...
https://epubs.rcsi.ie/psycholart/18
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Designing for the Future: A Complex Systems Approach to Communication Networks
(2020)
DZAFERAGIC, MERIM
Designing for the Future: A Complex Systems Approach to Communication Networks
(2020)
DZAFERAGIC, MERIM
Abstract:
The network size and the deployment density of wireless networks continue to increase from year to year. Additionally, networks are experiencing an operational shift that affects both: (1) the network architecture, and (2) the service implementation. The network architecture is changing from a traditionally rigid hierarchical - hardware first - to a more flat and flexible - software first - implementation. This shift enables innovation related to, among other things, network infrastructure ownership, dynamic resource sharing, on-demand resource allocation. The evolution of the network architecture underpins the shift related to the service implementation. New services have strict requirements (e.g. latency, throughput, reliability), dynamically demanding resources on a more granular level. The growing size and operational changes demand scalability and adaptability to be part of the network design. Not only are individual networks becoming more sophisticated, but it is increasingly ...
http://hdl.handle.net/2262/91504
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Developing climate smart agriculture: Insights from Indonesia, Vietnam, Malawi and Ireland
(2019)
Duffy, Colm
Developing climate smart agriculture: Insights from Indonesia, Vietnam, Malawi and Ireland
(2019)
Duffy, Colm
Abstract:
The present and future challenges to agricultural development and food security are immense. The agricultural sector is a significant driver of climate change, but at the same time, is highly vulnerable to its impacts. Climate smart agriculture is a framework for sustainable agricultural development, which has been touted as having significant potential to enhance the development of climate resilient pathways for agriculture, while at the same time taking advantage of opportunities to enhance mitigation. However, considering the relative newness of the concept, there is still much research needed with regards to its development at both local and national levels. This thesis attempts to contribute to the development of climate smart agriculture along three main themes: (i) planning and development, (ii) adaptation and (iii) mitigation. From a supranational perspective, the research contributes to the enhancement of indicators for climate smart agriculture, while at the national leve...
http://hdl.handle.net/10379/15577
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Does the lack of mannitol accumulation in an isolate ofrhodella maculata(rhodellophyceae, rhodophyta) from the brackish baltic sea indicate a stressed population at the distribution limit?
(2018)
Nitschke, Udo; Boedeker, Christian; Karsten, Ulf; Hepperle, Dominik; Eggert, Anja
Does the lack of mannitol accumulation in an isolate ofrhodella maculata(rhodellophyceae, rhodophyta) from the brackish baltic sea indicate a stressed population at the distribution limit?
(2018)
Nitschke, Udo; Boedeker, Christian; Karsten, Ulf; Hepperle, Dominik; Eggert, Anja
Abstract:
The unicellular red alga Rhodella maculata Evans is reported for the first time from the central Baltic Sea (habitat salinity 5 psu). To evaluate whether this Baltic isolate is locally adapted to the brackish environment, its salt stress response was compared with a marine isolate (33 psu) by measuring growth rates, photosynthetic performance and the concentration of the osmolyte mannitol as a function of changing salinity between 1 and 60 psu. The brackish Baltic isolate grew between 5 and 40 psu, a narrower salinity range than in the marine isolate (1-60 psu). The marine isolate of R. maculata showed adaptations to an intertidal habitat with fluctuating salinities rather than to stable salinity conditions. The cells of the marine isolate performed a pronounced regulation of primary photosynthesis via non-photochemical quenching (NPQ), and accumulation of mannitol was involved in osmotic acclimation as intracellular concentrations increased considerably with rising salinities from ...
http://hdl.handle.net/10379/13139
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Dragonfly: a tool for simulating self-adaptive drone behaviours
(2019)
Maia, Paulo Henrique; Vieira, Lucas; Chagas, Matheus; Yu, Yijun; Zisman, Andrea; Nuseib...
Dragonfly: a tool for simulating self-adaptive drone behaviours
(2019)
Maia, Paulo Henrique; Vieira, Lucas; Chagas, Matheus; Yu, Yijun; Zisman, Andrea; Nuseibeh, Bashar
Abstract:
Drone simulators can provide an abstraction of different applications of drones and facilitate reasoning about distinct situations, in order to evaluate the effectiveness of these applications. In this paper we describe Dragonfly, a simulator of the behaviours of individual and collection of drones in various environments, involving random contextual variables and different environmental settings. Dragonfly supports the use of several drones in applications and evaluates the satisfaction of requirements under normal and exceptional situations. It simulates adaptive behaviours of drones due to exceptional situations. The adaption of drones is based on the use of wrappers implemented using aspect-oriented programming.
http://hdl.handle.net/10344/8410
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Drivers and barriers of adaptation initiatives – How societal transformation affects natural hazard management and risk mitigation in Europe
(2019)
Thaler, Thomas; Attems, Marie-Sophie; Bonnefond, Mathieu; Clarke, Darren; Gatien-Tourna...
Drivers and barriers of adaptation initiatives – How societal transformation affects natural hazard management and risk mitigation in Europe
(2019)
Thaler, Thomas; Attems, Marie-Sophie; Bonnefond, Mathieu; Clarke, Darren; Gatien-Tournat, Amandine; Gralepois, Mathilde; Fournier, Marie; Murphy, Conor; rauter, Magdalena; papathoma-köhle, Maria; Servain, Sylvie; Fuchs, Sven
Abstract:
A key challenge of hazard risk management is finding novel ways to respond to future extremes amid increasing vulnerability. Societal transformation in the context of multi-functional protection schemes offers potential in this regard. However, the drivers and barriers of societal transformation in hazard management are poorly understood. Here we interrogate drivers and barriers of societal transformation in natural hazard management through case studies in Austria, France and Ireland focusing on attempts to integrate multi-functional protection schemes in the context of flood and avalanche hazards. We conducted qualitative semi-structured interviews with key stakeholders connected to proposed transformative strategies in the selected case studies. We find that transformative approaches have been mainly supported by local initiatives instigated by local governments, residents, or NGOs with the aim of complementing conventional hazard management policies. Our analysis shows that loca...
http://mural.maynoothuniversity.ie/13848/
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Effects of temperature and salinity on the survival and development of larval and juvenile palaemon serratus (decapoda: palaemonidae) from irish waters
(2018)
Kelly, Eoghan; Tully, Oliver; Browne, Ronan
Effects of temperature and salinity on the survival and development of larval and juvenile palaemon serratus (decapoda: palaemonidae) from irish waters
(2018)
Kelly, Eoghan; Tully, Oliver; Browne, Ronan
Abstract:
The combined effects of temperature and salinity on the survival and development of larval and juvenile Palaemon serratus from the west coast of Ireland were investigated. Survival over time was measured at thirty combinations of temperature and salinity ranging from 10-19 degrees C and 9-34 parts per thousand in a fully factorial design. Salinity had a stronger influence than temperature on survival at all larval stages except stage V. For juveniles the main effect changed from temperature between 100 and 200 degree days to salinity between 200 and 600 degree days and temperature between 600 and 800 degree days. Estimates of time taken to 50% mortality showed that juveniles tolerated lower salinities for longer periods and exhibited optimal salinity values which were 3 parts per thousand lower than larvae, at temperatures between 10 and 15 degrees C. Larval stage durations were found to be influenced by temperature but not salinity. Comparison with published data suggests that popu...
http://hdl.handle.net/10379/12205
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Enabling Adaptation in Trust Computations
(2009)
Longo, Luca; Dondio, Pierpaolo; Riccardo, Bresciani; Butterfield, Andrew; Barrett, Stephen
Enabling Adaptation in Trust Computations
(2009)
Longo, Luca; Dondio, Pierpaolo; Riccardo, Bresciani; Butterfield, Andrew; Barrett, Stephen
Abstract:
Digital systems have been rapidly evolving within highly dynamic and unstructured environments, where the lack of a central authority forces entities to interact with each other through collaboration and negotiation. Digital agents often use Trust models in order to compute the level of trustworthiness of the partner they want to collaborate with. Unfortunately, due to the evolution speed of open and collaborative environments, the trustworthiness of an agent varies over time, and as a result, Trust models must be continuously adapted to the changing context. In this work we address the problem by presenting a self-adaptive model for Trust computations. In particular, the proposed methodology seeks to continuously align the trust model in force with the changing context in Web 2.0 dynamic applications such as forums, blogs, p2p systems. The self-adaptation is reflected in the auto-organisation of the Trust function to obtain an accurate degree of agents' trustworthiness.
https://arrow.dit.ie/scschcomcon/185
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Engineering adaptive privacy: on the role of privacy awareness requirements
(2013)
Omoronyia, Inah; Cavallaro, Luca; Salehie, Mazeiar; Pasquale, Liliana; Nuseibeh, Bashar
Engineering adaptive privacy: on the role of privacy awareness requirements
(2013)
Omoronyia, Inah; Cavallaro, Luca; Salehie, Mazeiar; Pasquale, Liliana; Nuseibeh, Bashar
Abstract:
Applications that continuously gather and disclose personal information about users are increasingly common. While disclosing this information may be essential for these applications to function, it may also raise privacy concerns. Partly, this is due to frequently changing context that introduces new privacy threats, and makes it difficult to continuously satisfy privacy requirements. To address this problem, applications may need to adapt in order to manage changing privacy concerns. Thus, we propose a framework that exploits the notion of privacy awareness requirements to identify runtime privacy properties to satisfy. These properties are used to support disclosure decision making by applications. Our evaluations suggest that applications that fail to satisfy privacy awareness requirements cannot regulate users’ information disclosure. We also observe that the satisfaction of privacy awareness requirements is useful to users aiming to minimise exposure to privacy threats, and to...
http://hdl.handle.net/10344/3145
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Exile, pistols, and promised lands: Ibsen and Israeli modernist writers
(2019)
Ruppo, Irina
Exile, pistols, and promised lands: Ibsen and Israeli modernist writers
(2019)
Ruppo, Irina
Abstract:
Allusions to Henrik Ibsen's plays in the works of two prominent Israeli modernist writers, Amos Oz s autobiographical A Tale of Love and Darkness (2004) and David Grossman s The Zigzag Kid (1994) examined in the context of the Israeli reception of Ibsen in the 1950s and 1960s. To establish the variety of meanings Ibsen s plays had for the audiences of the Habimah production of Peer Gynt in 1952 and The Kameri production of Hedda Gabler in 1966, this article draws on newspaper reviews and actors memoirs, as well as providing an analysis of Leah Goldberg s translation of Peer Gynt. It emerges that both authors enlisted Ibsen in their exploration of the myths surrounding the formation of Israeli nationhood and identity.
This research was funded by NUI Galway College of Arts, Social Sciences, and Celtic Studies Research Support Scheme 2018.
http://hdl.handle.net/10379/15573
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Experiments in Adaptation-Guided Retrieval in Case-Based Design
(1994)
Smyth, Barry; Keane, Mark T.
Experiments in Adaptation-Guided Retrieval in Case-Based Design
(1994)
Smyth, Barry; Keane, Mark T.
Abstract:
TCD-CS-94-17
Case-based reasoning (CBR) has been applied with some success to complex planning and design tasks. In such systems, the best case is retrieved and adapted to solve a particular target problem. In general, the best case is that which can be most easily adapted to the target problem (as the overhead in adaptation is often very high). Standard CBR systems use semantic-similarity to retrieve cases, on the assumption that the most similar case is the best or easiest case to adapt. However, this assumption can be shown to be unwarranted. In this paper, we report a novel retrieval method, called adaptation-guided retrieval, that is sensitive to the ease-ofadaptation of cases. In the context of a CBR system for software-design, called Deja Vu, we show through a series of experiments that adaptation-guided retrieval is more accurate than standard retrieval techniques, that it scales well to large casebases and that it results in more efficient overall problem-solving perfor...
http://hdl.handle.net/2262/12782
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Exposure to bile leads to the emergence of adaptive signalling variants in the opportunistic pathogen Pseudomonas aeruginosa
(2019)
Flynn, Stephanie; Reen, F. Jerry; O'Gara, Fergal
Exposure to bile leads to the emergence of adaptive signalling variants in the opportunistic pathogen Pseudomonas aeruginosa
(2019)
Flynn, Stephanie; Reen, F. Jerry; O'Gara, Fergal
Abstract:
The chronic colonization of the respiratory tract by the opportunistic pathogen Pseudomonas aeruginosa is the primary cause of morbidity and mortality in cystic fibrosis (CF) patients. P. aeruginosa has been shown to undergo extensive genomic adaptation facilitating its persistence within the CF lung allowing it to evade the host immune response and outcompete co-colonizing residents of the lung microbiota. However, whilst several studies have described the various mutations that frequently arise in clinical isolates of P. aeruginosa, the environmental factors governing the emergence of these genetic variants is less well characterized. Gastro-oesophageal reflux has recently emerged as a major co-morbidity in CF and is often associated with the presence of bile acids in the lungs most likely by (micro) aspiration. In order to investigate whether bile may select for genetic variants, P. aeruginosa was experimentally evolved in artificial sputum medium, a synthetic media resembling en...
http://hdl.handle.net/10468/8706
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Feature interaction in pervasive computing systems
(2008)
Liu, Yu; Meier, Rene
Feature interaction in pervasive computing systems
(2008)
Liu, Yu; Meier, Rene
Abstract:
Feature interaction describes a situation where the combination of two or more services that individually perform correctly results in unexpected and possibly adverse behaviour. Such feature interaction issues have first been identified in telecommunication systems and are now beginning to be considered in other distributed software systems.
http://hdl.handle.net/10344/372
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