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A new compound, 1-(2,2,3-trimethyl-1,3-oxazolidin-5-yl)-butane-1,2,3,4-tetrol, has been discovered, described,
and its crystal polymorphism investigated. The crystal structures of two polymorphs have been
solved with single-crystal X-ray diffraction. The molecule is chiral with four stereo centers, and both polymorphs
crystallise in the non-centrosymmetric orthorhombic, chiral P212121 space group, with one molecule
in the asymmetric unit. In both structures the molecules are arranged three dimensionally in an interlocked
manner, stabilized by strong O–H⋯O and weaker C–H⋯O and π⋯π interactions. The polymorphs
have been characterized by X-ray powder diffraction (XRPD) and infrared spectroscopy (IR). The thermodynamic
stability relationship between the polymorphs from 280 K up to the melting points has been quantitatively
determined by differential scanning calorimetry (DSC), through measurement of melting points,
heats of fusion, and heat capacities of the solid phases and the superco...
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