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Displaying Results 1 - 7 of 7 on page 1 of 1

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Application of face centred central composite design to optimise compression force and tablet diameter for the formulation of mechanically strong and fast disintegrating orodispersible tablets. (2012)

Pabari, Ritesh M; Ramtoola, Zebunnissa

Abstract:

The original article is also available at <a href="http://www.sciencedirect.com/science/article/pii/S0378517312002438" target="_blank">http://www.sciencedirect.com/science/article/pii/S0378517312002438</a>
A two factor, three level (3(2)) face centred, central composite design (CCD) was applied to investigate the main and interaction effects of tablet diameter and compression force (CF) on hardness, disintegration time (DT) and porosity of mannitol based orodispersible tablets (ODTs). Tablet diameters of 10, 13 and 15 mm, and CF of 10, 15 and 20 kN were studied. Results of multiple linear regression analysis show that both the tablet diameter and CF influence tablet characteristics. A negative value of regression coefficient for tablet diameter showed an inverse relationship with hardness and DT. A positive value of regression coefficient for CF indicated an increase in hardness and DT with increasing CF as a result of ...

http://epubs.rcsi.ie/spharmart/7

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Oral flucloxacillin and phenoxymethylpenicillin versus flucloxacillin alone for the emergency department outpatient treatment of cellulitis: study protocol for a randomised controlled trial. (2013)

Quirke, Michael; Wakai, Abel; Gilligan, Peadar; O'Sullivan, Ronan

Abstract:

The original article is available at <a href="http://www.trialsjournal.com">www.trialsjournal.com</a>
BACKGROUND: Oral flucloxacillin, either alone or in combination with phenoxymethylpenicillin, is a commonly prescribed antibiotic for the treatment of cellulitis, particularly in Ireland and the United Kingdom. This study aims to establish the non-inferiority of oral monotherapy (flucloxacillin alone) to dual therapy (flucloxacillin and phenoxymethylpenicillin) for the outpatient treatment of cellulitis in adults. METHODS/DESIGN: This study is a multicentre, randomised, double-blind, placebo-controlled trial of adults who present to the emergency department (ED) with cellulitis that is deemed treatable on an outpatient basis with oral antibiotics. After fulfilling specified inclusion and exclusion criteria, informed consent will be taken. Patients will be given a treatment pack containing 7 days of treatment wi...

http://epubs.rcsi.ie/gpart/36

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Over-the-counter medications for acute cough in children and adults in ambulatory settings. (2008)

Smith, Susan M; Schroeder, Knut; Fahey, Tom

Over-the-counter medications for acute cough in children and adults in ambulatory settings. (2008)

Smith, Susan M; Schroeder, Knut; Fahey, Tom

Abstract:

This article is also available at <a href="http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD001831.pub3/epdf">http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD001831.pub4/epdf</a>
BACKGROUND: Acute cough due to upper respiratory tract infection (URTI) is a common symptom. Non-prescription over-the-counter (OTC) medicines are frequently recommended as a first-line treatment, but there is little evidence as to whether these drugs are effective. OBJECTIVES: To assess the effects of oral OTC cough preparations for acute cough. SEARCH STRATEGY: We searched the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2006, Issue 4); MEDLINE (January 1966 to January Week 1, 2007); EMBASE (January 1974 to January 2007); and the UK Department of Health National Research Register (June 2007). SELECTION CRITERIA: Randomised controlled trials (RCTs) comp...

http://epubs.rcsi.ie/gpart/84

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Prevalence and predictors of initial oral antibiotic treatment failure in adult emergency department patients with cellulitis: a pilot study. (2015)

Quirke, Michael; Boland, Fiona; Fahey, Tom; O'Sullivan, Ronan; Hill, Arnold DK; St...

Prevalence and predictors of initial oral antibiotic treatment failure in adult emergency department patients with cellulitis: a pilot study. (2015)

Quirke, Michael; Boland, Fiona; Fahey, Tom; O'Sullivan, Ronan; Hill, Arnold DK; Stiell, Ian; Wakai, Abel

Abstract:

The original article is available at http://bmjopen.bmj.com
INTRODUCTION: Assessment of cellulitis severity in the emergency department (ED) setting is problematic. Given the lack of research performed to describe the epidemiology and management of cellulitis, it is unsurprising that heterogeneous antibiotic prescribing and poor adherence to guidelines is common. It has been shown that up to 20.5% of ED patients with cellulitis require either a change in route or dose of the initially prescribed antibiotic regimen. The current treatment failure rate for empirically prescribed oral antibiotic therapy in Irish EDs is unknown. The association of patient risk factors with treatment failure has not been described in our setting. Lower prevalence of community-acquired methicillin-resistant Staphylococcus aureus-associated infection, differing antibiotic prescribing preferences and varying availability of outpatient intravenous therapy programmes may result ...

http://epubs.rcsi.ie/surgart/41

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Stability of an alternative extemporaneous captopril fast-dispersing tablet formulation versus an extemporaneous oral liquid formulation. (2012)

Pabari, Ritesh M; McDermott, Claire; Barlow, James; Ramtoola, Zebunnissa

Stability of an alternative extemporaneous captopril fast-dispersing tablet formulation versus an extemporaneous oral liquid formulation. (2012)

Pabari, Ritesh M; McDermott, Claire; Barlow, James; Ramtoola, Zebunnissa

Abstract:

The original article is also available at <a href="http://www.sciencedirect.com/science/article/pii/S014929181200570X" target="_blank">http://www.sciencedirect.com/science/article/pii/S014929181200570X</a>
BACKGROUND: Administration of medications to pediatric patients is challenging because many drugs are not commercially available in appropriate dosage formulations and/or strengths. Consequently, these drugs are prepared extemporaneously as oral liquid (OL) formulations using marketed tablets or capsules. In many cases, the stability of these extemporaneous preparations, which may affect their tolerability, has not been documented. An alternative extemporaneous solid formulation, such as a fast-dispersing tablet (FDT), may offer enhanced stability as well as dosing flexibility because it may be administered as an orodispersible tablet or as a reconstituted suspension/solution. Although FDTs are available increasingly ...

http://epubs.rcsi.ie/spharmart/8

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The Emergence, Development and Influence of French Haute Cuisine on Public Dining in Dublin Restaurants 1900-2000: an Oral History (2009)

Mac Con Iomaire, Máirtín

The Emergence, Development and Influence of French Haute Cuisine on Public Dining in Dublin Restaurants 1900-2000: an Oral History (2009)

Mac Con Iomaire, Máirtín

Abstract:

The words Dublin or Ireland do not immediately come to mind when haute cuisine is mentioned. However, two leading French chefs, the brothers Francois and Michel Jammet, opened a restaurant in Dublin in 1901 which, up until its closure in 1967, remained one of the best restaurants serving haute cuisine in the world (Mac Con Iomaire 2005a; Mac Con Iomaire 2006). Haute cuisine was served in many Dublin hotels, clubs and restaurants during the twentieth century and came under similar influences as London and other European cities, moving from the Escoffier orthodoxy to the influence of nouvelle cuisine. This research reveals that French haute cuisine was widely available in Dublin hotels and restaurants from the late nineteenth century. German and Austrian chefs and waiters were widely employed in Dublin until the First World War, after which, Swiss chefs became more prevalent. Dublin restaurants enjoyed increased business during the ‘Emergency’ as gastro-tourists and army offi...

http://arrow.dit.ie/tourdoc/12

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Using Storytelling Tools for Students Presentations (2016)

Hascoet, Valerie

Using Storytelling Tools for Students Presentations (2016)

Hascoet, Valerie

Abstract:

As a response to increased group size, I have been developing the use of “digital storytelling” as an alternative form of oral assessment. As well as completing a face-to-face oral assignment, some of my groups produce animated slideshows with a voiceover in lieu of formal presentations. The following article which I contributed to the TELU (Technology Enhanced Learning for You) website in July 2016 describes my approach.

http://arrow.dit.ie/aaschlanoth/7

Displaying Results 1 - 7 of 7 on page 1 of 1