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Displaying Results 76 - 100 of 213 on page 4 of 9
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Genetic variation indnmt3band increased global dna methylation is associated with suicide attempts in psychiatric patients
(2018)
Murphy, T. M.; Mullins, N.; Ryan, M.; Foster, T.; Kelly, C.; McClelland, R.; O'Gra...
Genetic variation indnmt3band increased global dna methylation is associated with suicide attempts in psychiatric patients
(2018)
Murphy, T. M.; Mullins, N.; Ryan, M.; Foster, T.; Kelly, C.; McClelland, R.; O'Grady, J.; Corcoran, E.; Brady, J.; Reilly, M.; Jeffers, A.; Brown, K.; Maher, A.; Bannan, N.; Casement, A.; Lynch, D.; Bolger, S.; Buckley, A.; Quinlivan, L.; Daly, L.
Abstract:
Recently, a significant epigenetic component in the pathology of suicide has been realized. Here we investigate candidate functional SNPs in epigenetic-regulatory genes, DNMT1 and DNMT3B, for association with suicide attempt (SA) among patients with co-existing psychiatric illness. In addition, global DNA methylation levels [5-methyl cytosine (5-mC%)] between SA and psychiatric controls were quantified using the Methylflash Methylated DNA Quantification Kit. DNA was obtained from blood of 79 suicide attempters and 80 non-attempters, assessed for DSM-IV Axis I disorders. Functional SNPs were selected for each gene (DNMT1; n?=?7, DNMT3B; n?=?10), and genotyped. A SNP (rs2424932) residing in the 3' UTR of the DNMT3B gene was associated with SA compared with a non-attempter control group (P?=?0.001; Chi-squared test, Bonferroni adjusted P value?=?0.02). Moreover, haplotype analysis identified a DNMT3B haplotype which differed between cases and controls, however this association did...
http://hdl.handle.net/10379/13050
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Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer
(2018)
Michailidou, Kyriaki; Beesley, Jonathan; Lindstrom, Sara; Canisius, Sander; Dennis, Joe...
Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer
(2018)
Michailidou, Kyriaki; Beesley, Jonathan; Lindstrom, Sara; Canisius, Sander; Dennis, Joe; Lush, Michael J; Maranian, Mel J; Bolla, Manjeet K; Wang, Qin; Shah, Mitul; Perkins, Barbara J; Czene, Kamila; Eriksson, Mikael; Darabi, Hatef; Brand, Judith S; Bojesen, Stig E; Nordestgaard, Børge G; Flyger, Henrik; Nielsen, Sune F; Rahman, Nazneen
Abstract:
Genome-wide association studies (GWAS) and large-scale replication studies have identified common variants in 79 loci associated with breast cancer, explaining similar to 14% of the familial risk of the disease. To identify new susceptibility loci, we performed a meta-analysis of 11 GWAS, comprising 15,748 breast cancer cases and 18,084 controls together with 46,785 cases and 42,892 controls from 41 studies genotyped on a 211,155-marker custom array (iCOGS). Analyses were restricted to women of European ancestry. We generated genotypes for more than 11 million SNPs by imputation using the 1000 Genomes Project reference panel, and we identified 15 new loci associated with breast cancer at P < 5 x 10(-8). Combining association analysis with ChIP-seq chromatin binding data in mammary cell lines and ChIA-PET chromatin interaction data from ENCODE, we identified likely target genes in two regions: SETBP1 at 18q12.3 and RNF115 and PDZK1 at 1q21.1. One association appears to be ...
http://hdl.handle.net/10379/12884
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Gout and the risk of advanced chronic kidney disease in the UK health system: a national cohort study
(2019)
Stack, Austin G.; Johnson, Michelle Elizabeth; Blak, Betina; Klein, Alyssa; Carpenter, ...
Gout and the risk of advanced chronic kidney disease in the UK health system: a national cohort study
(2019)
Stack, Austin G.; Johnson, Michelle Elizabeth; Blak, Betina; Klein, Alyssa; Carpenter, Lewis; Morlock, Robert; Maguire, Andrew R.; Parsons, Victoria L.
Abstract:
Objective Evaluate the association between gout and riskof advanced chronic kidney disease (CKD).Design Retrospective matched cohort study.Setting UK Clinical Practice Research Datalink.Participants The analysis included data for 68 897patients with gout and 554 964 matched patients withoutgout. Patients were aged ≥18 years, registered at UKpractices, had ≥12 months of clinical data and haddata linked with Hospital Episode Statistics. Patientswere excluded for history of advanced CKD, juvenilegout, cancer, HIV, tumour lysis syndrome, Lesch-Nyhansyndrome or familial Mediterranean fever.Primary and secondary outcome measures AdvancedCKD was defined as first occurrence of: (1) dialysis, kidneytransplant, diagnosis of end-stage kidney disease (ESKD)or stage 5 CKD (diagnostic codes in Read system orInternational Classification of Diseases, Tenth Revision);(2) estimated glomerular filtration rate (eGFR) <10 mL/min/1.73 m²; (3) doubling of serum creatinine frombaseline and (4) death ass...
http://hdl.handle.net/10344/8109
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Guardedness in communications between people experiencing acute psychosis and mental health nurses
(2016)
Sean, Boland
Guardedness in communications between people experiencing acute psychosis and mental health nurses
(2016)
Sean, Boland
Abstract:
Mental health nurses are the largest cohort of clinicians working in Irish Mental Health services, and are usually involved in the care of service users experiencing acute psychosis either as in-patients, mental health community facilities or in the service users own home. Some service users place value on communication with nurses as it helps with easing their difficulties (Gilburt, Rose and Slade 2008; Russo and Hamilton 2007, however others report not been listened to, ignored and disempowered (Octwell and Capital Members 2007). In addition, both groups worry about risk and vulnerability when communicating with each other (Norwood 2007;Duxbury and Whittington 2005).Consequently, understanding the process of how these two groups manage to communicate together is worthy of study as research into this area is limited. Hence, this Classic Grounded Theory study aimed to address these gaps by developing a substantive theory pertaining to the phenomena of communications between nurses a...
http://doras.dcu.ie/21413/
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Guest Editorial: Americans Post 9/11: From Pride to Terror
(2014)
Korstanje, Maximiliano E, Prof
Guest Editorial: Americans Post 9/11: From Pride to Terror
(2014)
Korstanje, Maximiliano E, Prof
https://arrow.dit.ie/ijrtp/vol2/iss1/3
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Guidance Booklet on Safe Handling of Nanoparticles
(2008)
McCormack, Declan; Malanowski, Norbert; Sermon, Paul; Hoeck, Juergen
Guidance Booklet on Safe Handling of Nanoparticles
(2008)
McCormack, Declan; Malanowski, Norbert; Sermon, Paul; Hoeck, Juergen
Abstract:
Nanotechnologies are a fast evolving scientific and technological field with a high potential impact on science, economy and society. Like with all new and quickly developing technologies it is important to weigh benefits versus risks at the earliest possible convenience. Building on the results of the ImPart project, this booklet is intended to give a review of the actual knowledge in the field of nanospecific risks, deriving recommendations for the safe handling of nanoparticles for executives in industry, public organizations and NGOs. This booklet is also intended to give an outlook on possible developments in the near future and "life after ImPart".
https://arrow.dit.ie/scschcpsart/19
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Health policy and the policymaking system: a case study of primary care in Ireland
(2016)
Kelly, Niall; Garvey, John; Palcic, Dónal
Health policy and the policymaking system: a case study of primary care in Ireland
(2016)
Kelly, Niall; Garvey, John; Palcic, Dónal
Abstract:
In 2001 the Irish government published a reforming policy intended to modernise and expand the delivery of primary care in Ireland. Fifteen years later, the Irish health system remains beset by problems indicative of a fragmented and underdeveloped primary care system. This case study examines the formation and implementation of the 2001 primary care policy and identifies key risk categories within the policymaking process itself that inhibited the timely achievement of policy objectives. Our methodology includes a directed content analysis of the policy formation and implementation documents and the influencing academic literature, as well as semi-structured interviews with key personnel involved in the process. We identify three broad risk categories - power, resources and capability - within the policymaking process that strongly influenced policy formation and implementation. We additionally show that the disjoint between policy formation and policy implementation was a conteste...
http://hdl.handle.net/10344/5538
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Hedging Effectiveness under Conditions of Asymmetry
(2012)
Hanly, Jim; Cotter, John
Hedging Effectiveness under Conditions of Asymmetry
(2012)
Hanly, Jim; Cotter, John
Abstract:
We examine whether hedging effectiveness is affected by asymmetry in the return distribution by applying tail specific metrics, for example, Value at Risk, to compare the hedging effectiveness of short and long hedgers. Comparisons are applied to a number of hedging strategies including OLS, and both symmetric and asymmetric GARCH models. We apply our analysis to a dataset consisting of S&P500 index cash and futures containing symmetric and asymmetric return distributions chosen ex-post. Our findings show that asymmetry reduces out-of-sample hedging performance and that significant differences occur in hedging performance between short and long hedgers.
https://arrow.dit.ie/buschacart/17
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High-resolution flood modeling of urban areas using msn_flood
(2018)
Hartnett, Michael; Nash, Stephen
High-resolution flood modeling of urban areas using msn_flood
(2018)
Hartnett, Michael; Nash, Stephen
http://hdl.handle.net/10379/11829
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How does social capital impede innovation? The mediating role of social decision-making constraints in a multilevel model
(2016)
Wang, Zhan
How does social capital impede innovation? The mediating role of social decision-making constraints in a multilevel model
(2016)
Wang, Zhan
Abstract:
Various conceptual and empirical studies demonstrate that social capital is a powerful factor in fostering innovation. However, most research focuses solely on the benefits of social capital without considering potential downsides. Further research is needed to consider potential risks or negative consequences of social capital to develop a more objective understanding of social capital’s potential negative outcomes. Moreover, social capital studies tend to examine social capital at only a single level, such as at the individual-level or firm-level, neglecting the effects operating simultaneously at both levels. This research develops a multilevel model to hypothesize social decision-making constraints as the mediator between social capital and firm innovation. Furthermore, this study also considers culture as a moderator that exerts moderating effects on the relationship between social capital and social decision-making constraints. Social capital and social decision-making constra...
http://hdl.handle.net/10344/5207
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How smoke-free laws improve air quality: a global study of irish pubs
(2018)
Connolly, Gregory N.; Carpenter, Carrie M.; Travers, Mark J.; Cummings, K. Michael; Hyl...
How smoke-free laws improve air quality: a global study of irish pubs
(2018)
Connolly, Gregory N.; Carpenter, Carrie M.; Travers, Mark J.; Cummings, K. Michael; Hyland, Andrew; Mulcahy, Maurice; Clancy, Luke
Abstract:
The present study examined indoor air quality in a global sample of smoke-free and smoking-permitted Irish pubs. We hypothesized that levels of respirable suspended particles, an important marker of secondhand smoke, would be significantly lower in smoke-free Irish pubs than in pubs that allowed smoking. Indoor air quality was assessed in 128 Irish pubs in 15 countries between 21 January 2004 and 10 March 2006. Air quality was evaluated using an aerosol monitor, which measures the level of fine particle (PM(2.5)) pollution in the air. A standard measurement protocol was used by data collectors across study sites. Overall, the level of air pollution inside smoke-free Irish pubs was 93% lower than the level found in pubs where smoking was permitted. Levels of indoor air pollution can be massively reduced by enacting and enforcing smoke-free policies.
http://hdl.handle.net/10379/10878
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Human Factors Issues and the Risk of High Voltage Equipment: Are Standards Sufficient to Ensure Safety by Design?
(2016)
Leva, Maria Chiara; Pirani, Roberta; Michela, Micaela de; Clancy, Paul
Human Factors Issues and the Risk of High Voltage Equipment: Are Standards Sufficient to Ensure Safety by Design?
(2016)
Leva, Maria Chiara; Pirani, Roberta; Michela, Micaela de; Clancy, Paul
Abstract:
High voltage equipment is mostly designed according to technically prescriptive standards requirements based on electrical engineering safety principles. However a more risk-based approach to standards and regulation may be advisable to enable designer and user to take an active role in establishing that their installation is inherently safe. The use of Gas Insulated Switchgear (GIS) for instance is enabling the new substation to be housed indoors and condensed into around one quarter of the space. The manufacturers argue that design improvements in GIS make it virtually “maintenance free”, comply with all the relevant standards. However some of these improvements have implications for the operators that need to be taken into account. Commissioning, operational checks and inspections and the occasional maintenance interventions are activities during which the technicians need to interface with the equipment, the issues regarding the interfaces provided have been analysed to identify...
https://arrow.dit.ie/schfsehart/236
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Human papillomavirus status of head and neck cancer as determined in cytologic specimens using the hybrid-capture 2 assay
(2018)
Smith, David F.; Maleki, Zahra; Coughlan, Diarmuid; Gooi, Zhen; Akpeng, Belinda; Ogawa,...
Human papillomavirus status of head and neck cancer as determined in cytologic specimens using the hybrid-capture 2 assay
(2018)
Smith, David F.; Maleki, Zahra; Coughlan, Diarmuid; Gooi, Zhen; Akpeng, Belinda; Ogawa, Takenori; Bishop, Justin A.; Frick, Kevin D.; Agrawal, Nishant; Gourin, Christine G.; Ha, Patrick K.; Koch, Wayne M.; Richmon, Jeremy D.; Westra, William H.; Pai, Sara I.
http://hdl.handle.net/10379/13946
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Identification and characterization of prodromal risk syndromes in young adolescents in the community: a population-based clinical interview study.
(2012)
Kelleher, Ian; Murtagh, Aileen; Molloy, Charlene; Roddy, Sarah; Clarke, Mary C; Harley,...
Identification and characterization of prodromal risk syndromes in young adolescents in the community: a population-based clinical interview study.
(2012)
Kelleher, Ian; Murtagh, Aileen; Molloy, Charlene; Roddy, Sarah; Clarke, Mary C; Harley, Michelle; Cannon, Mary
Abstract:
<p><em>This is a pre-copy-editing, author-produced PDF of an article accepted for publication in Schizophrenia Bulletin</em> <em>following peer review. The definitive publisher-authenticated version Kelleher I, Molloy C, Roddy S, Clarke MC, Harley M, Cannon M. Identification and characterization of prodromal risk syndromes in young adolescents in the community: a population-based clinical interview study. Schizophrenia Bulletin. 2012;38(2):239-46</em> <em>is available online at: <a href="http://schizophreniabulletin.oxfordjournals.org/content/38/2/239.long">http://schizophreniabulletin.oxfordjournals.org/content/38/2/239.long</a></em></p>
<p>While a great deal of research has been conducted on prodromal risk syndromes in relation to help-seeking individuals who present to the clinic, there is a lack of research on prodromal risk syndromes in the general population. The current study aimed first to establ...
https://epubs.rcsi.ie/psychart/5
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Identification of novel genetic markers of breast cancer survival
(2018)
Guo, Qi; Schmidt, Marjanka K.; Kraft, Peter; Canisius, Sander; Chen, Constance; Khan, S...
Identification of novel genetic markers of breast cancer survival
(2018)
Guo, Qi; Schmidt, Marjanka K.; Kraft, Peter; Canisius, Sander; Chen, Constance; Khan, Sofia; Tyrer, Jonathan; Bolla, Manjeet K.; Wang, Qin; Dennis, Joe; Michailidou, Kyriaki; Lush, Michael; Kar, Siddhartha; Beesley, Jonathan; Dunning, Alison M.; Shah, Mitul; Czene, Kamila; Darabi, Hatef; Eriksson, Mikael; Lambrechts, Diether
Abstract:
Background: Survival after a diagnosis of breast cancer varies considerably between patients, and some of this variation may be because of germline genetic variation. We aimed to identify genetic markers associated with breast cancer-specific survival. Methods: We conducted a large meta-analysis of studies in populations of European ancestry, including 37 954 patients with 2900 deaths from breast cancer. Each study had been genotyped for between 200 000 and 900 000 single nucleotide polymorphisms (SNPs) across the genome; genotypes for nine million common variants were imputed using a common reference panel from the 1000 Genomes Project. We also carried out subtype-specific analyses based on 6881 estrogen receptor (ER)-negative patients (920 events) and 23 059 ER-positive patients (1333 events). All statistical tests were two-sided. Results: We identified one new locus (rs2059614 at 11q24.2) associated with survival in ER-negative breast cancer cases (hazard ratio [HR] = 1.95, 95% c...
http://hdl.handle.net/10379/11766
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IGDT Based Robust Decision Making Tool for DNOs in Load Procurement Under Severe Uncertainty
(2014)
Soroudi, Alireza; Ehsan, Mehdi
IGDT Based Robust Decision Making Tool for DNOs in Load Procurement Under Severe Uncertainty
(2014)
Soroudi, Alireza; Ehsan, Mehdi
Abstract:
This paper presents the application of Information Gap Decision Theory (IGDT) to help the Distribution Network Operators (DNOs) in choosing the supplying resources for meeting the demand of their customers. The three main energy resources are pool market, Distributed Generations (DGs) and the bilateral contracts. In deregulated environment, the DNO is faced with many uncertainties associated to the mentioned resources which may not have enough information about their nature and behaviors. In such cases, the classical methods like probabilistic methods or fuzzy methods are not applicable for uncertainty modeling because they need some information about the uncertainty behaviors like Probability Distribution Function (PDF) or their membership functions. In this paper, a decision making framework is proposed based on IGDT model to solve this problem. The uncertain parameters considered here, are as follows: price of electricity in pool market, demand of each bus and the decisions of DG...
http://hdl.handle.net/10197/6173
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Impact of pharmacist counselling on clozapine knowledge
(2017)
Ní Dhubhlaing, Ciara; Young, Ailish; Sahm, Laura J.
Impact of pharmacist counselling on clozapine knowledge
(2017)
Ní Dhubhlaing, Ciara; Young, Ailish; Sahm, Laura J.
Abstract:
Clozapine is the only antipsychotic with evidence for efficacy in treatment of resistant schizophrenia but it carries a high side effect burden. Patient information is provided but may be poorly retained. This study aims to examine the impact of pharmacist counselling upon patient knowledge of clozapine. Outpatients, aged 18 years and over, attending St. Patrick's University Hospital, Dublin, participated in this study between June and August 2015. The intervention consisted of pharmacist counselling on two occasions one month apart. Knowledge was assessed using a 28-point checklist devised from the currently available clozapine patient information sources, at baseline and after each counselling session. Ethics approval was obtained. Twenty-five participants (40% female; mean age 45.1 years, SD 9.82; 64% unemployed, 28% smokers) showed an improvement in knowledge scores of clozapine from baseline to postcounselling on each occasion with an overall improvement in knowledge score...
http://hdl.handle.net/10468/6335
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Impact of the choice of normalization method on molecular cancer class discovery using nonnegative matrix factorization
(2018)
Yang, Haixuan; Seoighe, Cathal
Impact of the choice of normalization method on molecular cancer class discovery using nonnegative matrix factorization
(2018)
Yang, Haixuan; Seoighe, Cathal
Abstract:
Nonnegative Matrix Factorization (NMF) has proved to be an effective method for unsupervised clustering analysis of gene expression data. By the nonnegativity constraint, NMF provides a decomposition of the data matrix into two matrices that have been used for clustering analysis. However, the decomposition is not unique. This allows different clustering results to be obtained, resulting in different interpretations of the decomposition. To alleviate this problem, some existing methods directly enforce uniqueness to some extent by adding regularization terms in the NMF objective function. Alternatively, various normalization methods have been applied to the factor matrices; however, the effects of the choice of normalization have not been carefully investigated. Here we investigate the performance of NMF for the task of cancer class discovery, under a wide range of normalization choices. After extensive evaluations, we observe that the maximum norm showed the best performance, altho...
http://hdl.handle.net/10379/14481
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Interinstitutional variations in mode of birth after a previous caesarean section: a cross-sectional study in six german hospitals
(2018)
Gross, Mechthild M.; Matterne, Andrea; Berlage, Silvia; Kaiser, Annette; Lack, Nicholas...
Interinstitutional variations in mode of birth after a previous caesarean section: a cross-sectional study in six german hospitals
(2018)
Gross, Mechthild M.; Matterne, Andrea; Berlage, Silvia; Kaiser, Annette; Lack, Nicholas; Macher-Heidrich, Susanne; Misselwitz, Björn; Bahlmann, Franz; Falbrede, Jörg; Hillemanns, Peter; von Kaisenberg, Constantin; von Koch, Franz Edler; Schild, Ralf L.; Stepan, Holger; Devane, Declan; Mikolajczyk, Rafael
Abstract:
Aims: Regional and interinstitutional variations have been recognized in the increasing incidence of caesarean section. Modes of birth after previous caesarean section vary widely, ranging from elective repeat caesarean section (ERCS) and unplanned repeat caesarean section (URCS) after trial of labour to vaginal birth after caesarean section (VBAC). This study describes interinstitutional variations in mode of birth after previous caesarean section in relation to regional indicators in Germany. Material and methods: A cross-sectional study using the birth registers of six maternity units (n = 12,060) in five different German states (n = 370,209). Indicators were tested by chi(2) and relative deviations from regional values were expressed as relative risks and 95% confidence intervals. Results: The percentages of women in the six units with previous caesarean section ranged from 11.9% to 15.9% (P = 0.002). VBAC was planned for 36.0% to 49.8% (P = 0.003) of these women, but actually c...
http://hdl.handle.net/10379/11740
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International charter on cardiovascular prevention and rehabilitation
(2018)
Grace, Sherry L.; Warburton, Darren R.; Stone, James A.; Sanderson, Bonnie K.; Oldridge...
International charter on cardiovascular prevention and rehabilitation
(2018)
Grace, Sherry L.; Warburton, Darren R.; Stone, James A.; Sanderson, Bonnie K.; Oldridge, Neil; Jones, Jennifer; Wong, Nathan; Buckley, John P.
Abstract:
Cardiovascular disease remains the leading cause of death in both women and men globally and is a growing epidemic in low-to middle-income countries. Without systematic access to cardiac rehabilitation (CR), these individuals may experience multiple recurrent acute care events and suffer unnecessarily premature death. The 2 aims of this Charter are (1) to bring together national associations from around the world to harmonize efforts in promoting cardiovascular prevention and rehabilitation and (2) to document consensus among national associations globally, regarding the internationally common core elements and benefits of cardiovascular disease prevention and rehabilitation. The Global Charter on CR calls to action those responsible for administering patient care to (a) establish CR as an obligatory, not optional service, and (b) to support countries to establish and augment programs of CR to ensure broad access to these proven services. In addition, the Charter calls for CR organi...
http://hdl.handle.net/10379/11705
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Investigating the association of rs2910164 with cancer in irish patients
(2018)
McVeigh, Terri Patricia; Mulligan, Robert J; McVeigh, Una Mary; Owens, Patrick W; Mille...
Investigating the association of rs2910164 with cancer in irish patients
(2018)
McVeigh, Terri Patricia; Mulligan, Robert J; McVeigh, Una Mary; Owens, Patrick W; Miller, Nicola; Bell, Marcia; Sebag, Frederic; Guerin, Carole; Quill, Denis; Weidhaas, Joanne Barnes; Kerin, Michael; Lowery, Aoife J
Abstract:
Introduction: MicroRNAs (miRNAs) are small noncoding RNA molecules that exert post-transcriptional effects on gene expression by binding with cis-regulatory regions in target messenger RNA (mRNA). Polymorphisms in genes encoding miRNAs or in miRNA-mRNA binding sites confer deleterious epigenetic effects on cancer risk. miR-146a has a role in inflammation and may have a role as a tumour suppressor. The polymorphism rs2910164 in the MIR146A gene encoding pre-miR-146a has been implicated in several inflammatory pathologies, including cancers of the breast and thyroid, although evidence for the associations has been conflicting in different populations. We aimed to further investigate the association of this variant with these two cancers in an Irish cohort. Methods: The study group comprised patients with breast cancer (BC), patients with differentiated thyroid cancer (DTC) and unaffected controls. Germline DNA was extracted from blood or from saliva collected using the DNA Genotek Ora...
http://hdl.handle.net/10379/12855
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Irish farm succession and inheritance; an examination of farmers’ economic decision-making strategies as socially-constructed risk assessment
(2019)
Leonard, Brian
Irish farm succession and inheritance; an examination of farmers’ economic decision-making strategies as socially-constructed risk assessment
(2019)
Leonard, Brian
Abstract:
Intergenerational farm transfer is increasingly viewed as fundamental to the sustainability and development of global agriculture, with an expectation that younger farmers, with more effective and efficient production practices, will enter the sector. However, in the EU at least, this perspective is tempered by the reality of a slow rate of farm transfer to younger farmers, reflected in the rising average age of farmers, and reduction in the number of farmers aged under 35. There is growing concern that this demographic trend may have negative impacts on the agricultural industry. The question of what motivates decisions to transfer farms is a complex one, and agricultural policy to date has not appeared to adequately address and respond to the current trends towards an ageing farm population. The key aim of this study is to examine the phenomenon of farm generational renewal with a specific focus on the economic implications at individual farm level, with a view to better understan...
http://hdl.handle.net/10379/15097
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Is a motivational interviewing based lifestyle intervention for obese pregnant women across europe implemented as planned? process evaluation of the dali study
(2018)
Jelsma, Judith G. M.; Simmons, David; Gobat, Nina; Rollnick, Stephen; Blumska, Kinga; J...
Is a motivational interviewing based lifestyle intervention for obese pregnant women across europe implemented as planned? process evaluation of the dali study
(2018)
Jelsma, Judith G. M.; Simmons, David; Gobat, Nina; Rollnick, Stephen; Blumska, Kinga; Jans, Goele; Galjaard, Sander; Desoye, Gernot; Corcoy, Rosa; Juarez, Fabiola; Kautzky-Willer, Alexandra; Harreiter, Jürgen; van Assche, Andre; Devlieger, Roland; Timmerman, Dirk; Hill, David; Damm, Peter; Mathiesen, Elisabeth R.; Wender-Ożegowska, Ewa; Zawiejska, Agnieszka
Abstract:
Background: Process evaluation is an essential part of designing and assessing complex interventions. The vitamin D and lifestyle intervention study (DALI) study is testing different strategies to prevent development of gestational diabetes mellitus among European obese pregnant women with a body mass index &gt;= 29kg/m(2). The intervention includes guidance on physical activity and/or healthy eating by a lifestyle coach trained in motivational interviewing (MI). The aim of this study was to assess the process elements: reach, dose delivered, fidelity and satisfaction and to investigate whether these process elements were associated with changes in gestational weight gain (GWG). Methods: Data on reach, dose delivered, fidelity, and satisfaction among 144 participants were collected. Weekly recruitment reports, notes from meetings, coach logs and evaluation questionnaires (n = 110) were consulted. Fidelity of eight (out of twelve) lifestyle coach practitioners was assessed by...
http://hdl.handle.net/10379/12082
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Learning paper on dementia and risk
(2015)
Clarke, Charlotte
Learning paper on dementia and risk
(2015)
Clarke, Charlotte
Abstract:
This paper is part of a series of Learning Papers commissioned by Genio to explore learnings in practice on specific topics within Dementia. This paper results from a Dementia and Risk workshop, facilitated by Prof. Charlotte Clarke and attended by representatives of Genio supported dementia projects.
http://hdl.handle.net/10147/612318
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Living longer and feeling better: healthy lifestyle, self-rated health, obesity and depression in ireland
(2018)
Harrington, J.; Perry, I. J.; Lutomski, J.; Fitzgerald, A. P.; Shiely, F.; McGee, H.; B...
Living longer and feeling better: healthy lifestyle, self-rated health, obesity and depression in ireland
(2018)
Harrington, J.; Perry, I. J.; Lutomski, J.; Fitzgerald, A. P.; Shiely, F.; McGee, H.; Barry, M. M.; Van Lente, E.; Morgan, K.; Shelley, E.
Abstract:
Background: The combination of four protective lifestyle behaviours (being physically active, a non-smoker, a moderate alcohol consumer and having adequate fruit and vegetable intake) has been estimated to increase life expectancy by 14 years. However, the effect of adopting these lifestyle behaviours on general health, obesity and mental health is less defined. We examined the combined effect of these behaviours on self-rated health, overweight/obesity and depression. Methods: Using data from the Survey of Lifestyle Attitudes and Nutrition (SLAN) 2007 (), a protective lifestyle behaviour (PLB) score was constructed for 10 364 men and women (&gt; 18 years), and representative of the Republic of Ireland adult population (response rate 62%). Respondents scored a maximum of four points, one point each for being physically active, consuming five or more fruit and vegetable servings daily, a non-smoker and a moderate drinker. Results: One-fifth of respondents (20%) adopted four P...
http://hdl.handle.net/10379/11823
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