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Advances in three-dimensional rapid prototyping of microfluidic devices for biological applications
O'Neill, Paul F.; Ben Azouz, Aymen; Vázquez, Mercedes; Liu, Jinghang; Marczak, Steven; Slouka, Zdenek; Chang, Hsueh Chia; Diamond, Dermot; Brabazon, Dermot
The capability of 3D printing technologies for direct production of complex 3D structures in a single step has recently attracted an ever increasing interest within the field of microfluidics. Recently, ultrafast lasers have also allowed developing new methods for production of internal microfluidic channels within the bulk of glass and polymer materials by direct internal 3D laser writing. This review critically summarizes the latest advances in the production of microfluidic 3D structures by using 3D printing technologies and direct internal 3D laser writing fabrication methods. Current applications of these rapid prototyped microfluidic platforms in biology will be also discussed. These include imaging of cells and living organisms, electrochemical detection of viruses and neurotransmitters, and studies in drug transport and induced-release of adenosine triphosphate from erythrocytes.
Keyword(s): Materials; Production engineering; Mechanical engineering; Microfluidics; Cell biology; Biomechanics; Biomedical engineering
Publication Date:
Type: Other
Peer-Reviewed: Unknown
Language(s): English
Institution: Dublin City University
Citation(s): O'Neill, Paul F. ORCID: 0000-0002-5374-034X <>, Ben Azouz, Aymen, Vázquez, Mercedes ORCID: 0000-0002-9770-5562 <>, Liu, Jinghang, Marczak, Steven, Slouka, Zdenek, Chang, Hsueh Chia, Diamond, Dermot ORCID: 0000-0003-2944-4839 <> and Brabazon, Dermot ORCID: 0000-0003-3214-6381 <> (2014) Advances in three-dimensional rapid prototyping of microfluidic devices for biological applications. Biomicrofluidics, 8 (052112). ISSN 1932-1058
Publisher(s): AIP Publishing LLC
File Format(s): application/pdf
Related Link(s):,
First Indexed: 2014-11-12 05:08:20 Last Updated: 2019-02-09 06:22:44