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Prognostic value of the ABCD2 clinical prediction rule: a systematic review and meta-analysis
Galvin, Rose; Geraghty, Colm; Motterlini, Nicola; Dimitrov, Borislav D; Fahey, Tom
<p>This is a pre-copy-editing, author-produced PDF of an article accepted for publication in Family Practice following peer review. The definitive publisher-authenticated version Galvin R, Geraghty C, Motterlini N, Dimitrov BD, Fahey T. Prognostic value of the ABCD2 clinical prediction rule: a systematic review and meta-analysis. Family Practice. 2010;0:1-11 is available online at: <a href="http://fampra.oxfordjournals.org/content/early/2011/04/11/fampra.cmr008.long">http://fampra.oxfordjournals.org/content/early/2011/04/11/fampra.cmr008.long</a></p> <p>Purpose: The ABCD2 clinical prediction rule (CPR) is designed to predict early risk of stroke after transient ischaemic attack (TIA). The purpose of this systematic review with meta-analysis is to determine the predictive value of the ABCD2 at 7 and 90 days across three strata of risk. Methods: A systematic literature search was conducted to identify studies that validated the ABCD2. The derived rule was used as a predictive model and applied to subsequent validation studies. Comparisons were made between observed and predicted number of strokes stratified by risk group, low (0-3 points), moderate (4-5 points) and high (6-7 points). Pooled results are presented as risk ratios (RRs) with 95% confidence intervals, in terms of over-prediction (RR>1) or under-prediction (RR0.05). Conclusion: The ABCD2 is a useful CPR, particularly in relation to 7 day risk of stroke.</p>
Keyword(s): ABCD2; risk prediction; stroke; TIA; Medicine and Health Sciences
Publication Date:
2011
Type: Journal article
Peer-Reviewed: Yes
Institution: Royal College of Surgeons in Ireland
Citation(s): Galvin R, Geraghty C, Motterlini N, Dimitrov BD, Fahey T. Prognostic value of the ABCD2 clinical prediction rule: a systematic review and meta-analysis. Family Practice. 2010;0:1-11.
File Format(s): application/pdf
Related Link(s): http://epubs.rcsi.ie/gpart/7
First Indexed: 2015-07-31 15:35:41 Last Updated: 2018-02-13 07:21:57