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Ovarian serous adenocarcinoma identified during IVF: diagnostic approach, surgical management, and reproductive outcome.
Walsh, David J; Sills, Eric Scott; Shkrobot, Lyuda V; Gleeson, Noreen C; Sheppard, Mary N; Walsh, Anthony PH
<p>This article is also available from <a href="http://www.biomedcentral.com">www.biomedcentral.com</a></p> <p>BACKGROUND: To present a diagnostic evaluation and treatment strategy for serous adenocarcinoma of the ovary discovered during an in vitro fertilisation (IVF) sequence, and report on reproductive outcome after tumour resection and embryo transfer.</p> <p>CASE PRESENTATION: Cycle monitoring in IVF identified an abnormal ovarian lesion which was subjected to ultrasound-guided needle aspiration. Cytology suggested malignancy, and unilateral oophorectomy was performed after formal staging. After surgery, the patient underwent an anonymous donor oocyte IVF cycle which established a viable twin intrauterine pregnancy. No recurrence of cancer has been detected in the >72 month follow-up interval; mother and twin daughters continue to do well.</p> <p>CONCLUSION: Suspicious adnexal structures noted during controlled ovarian hyperstimulation for IVF warrant assessment, and this report confirms the role of aspiration cytology in such cases. If uterine conservation is possible, successful livebirth can be achieved from IVF if donor oocyes are utilised, as described here.</p>
Keyword(s): Adult; Cystadenocarcinoma; Serous; Female; Fertilization in Vitro; Humans; Ovarian Neoplasms; Pregnancy; Pregnancy Complications; Neoplastic; Medicine and Health Sciences; Obstetrics and Gynecology
Publication Date:
2009
Type: Journal article
Peer-Reviewed: Yes
Institution: Royal College of Surgeons in Ireland
Citation(s): Walsh DJ, Sills ES, Shkrobot LV, Gleeson NC, Sheppard MN, Walsh AP. Ovarian serous adenocarcinoma identified during IVF: diagnostic approach, surgical management, and reproductive outcome. World Journal of Surgical Oncology. 2009;7:46.
File Format(s): application/pdf
Related Link(s): http://epubs.rcsi.ie/obsgynart/6
First Indexed: 2015-07-31 15:36:24 Last Updated: 2018-02-13 07:20:44