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Determination optical properties of tissue-like phantoms using diffuse reflectance and transmittance spectroscopy
Lu, Huihui; Gunther, Jacqueline; Andersson-Engels, Stefan
We present a simple, convenient fibre-optics probe system for the determination optical properties of tissue-like liquid phantoms based on diffuse reflectance and transmittance measurements at the wavelength of visible-near-infrared region. The method combined Monte Carlo simulations, multiple polynomial regression and a Newton-Raphson algorithm for solving nonlinear equation system. In the range of optical properties of phantom with the μa at 0 – 0.5 cm-1 and the μs’ at 3 – 45 cm-1, the mean prediction error at 630 nm was 1.91 % for μs’ and 7.51 % for μa. The performance of the method is further tested by predictive error and validated using similar matrix of milk-ink phantoms on reflectance and transmittance.
Keyword(s): Optical properties; Spectroscopy; Fibre-optics; Tissue diagnostics
Publication Date:
2018
Type: Conference item
Peer-Reviewed: Yes
Language(s): English
Institution: University College Cork
Funder(s): Science Foundation Ireland
Citation(s): Lu, H., Gunther, J. and Andersson-Engels, S. (2018) 'Determination optical properties of tissue-like phantoms using diffuse reflectance and transmittance spectroscopy', Proceedings of SPIE 10820: Optics in Health Care and Biomedical Optics VIII, 108202X (7pp), SPIE/COS Photonics Asia 2018, Beijing, China, 11-13 October. doi:10.1117/12.2501183
Publisher(s): Society of Photo-optical Instrumentation Engineers (SPIE)
File Format(s): application/pdf
First Indexed: 2018-12-08 06:30:53 Last Updated: 2018-12-08 06:30:53