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Perspectives on the expansion of human precision oncology and genomic approaches to sea turtle fibropapillomatosis
Duffy, David J.; Martindale, Mark Q.
Our recent Communications Biology research article revealed the genomic drivers and therapeutic vulnerabilities of sea turtle fibropapillomatosis tumors. Fibropapillomatosis is a debilitating tumorous disease afflicting populations of green sea turtles globally. While a virus is involved in the development of this disease, it is increasingly understood that the key trigger is linked to anthropogenic disturbances of the environment. The specific environmental co-trigger(s) has yet to be functionally confirmed. Here we outline the next steps required to advance our understanding of this enigmatic disease, to enable us to more effectively clinically combat it and to ultimately tackle its environmental co-trigger to halt and hopefully reverse the spread of fibropapillomatosis.
Keyword(s): human precision oncology
Publication Date:
2019
Type: Journal article
Peer-Reviewed: Yes
Language(s): English
Institution: University of Limerick
Citation(s): Communications Bilogy;2:54
https://doi.org/10.1038/s42003-019-0301-1
17–033 R
SOSF 356
663830-BU115
Publisher(s): Nature Research
First Indexed: 2019-03-01 06:25:59 Last Updated: 2019-03-01 06:25:59