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Advances in magnetic tweezers for single molecule and cell biophysics
Kilinc, Devrim; Lee, Gil U.
Magnetic tweezers (MTW) enable highly accurate forces to be transduced to molecules to study mechanotransduction at the molecular or cellular level. We review recent MTW studies in single molecule and cell biophysics that demonstrate the flexibility of this technique. We also discuss technical advances in the method on several fronts, i.e., from novel approaches for the measurement of torque to multiplexed biophysical assays. Finally, we describe multi-component nanorods with enhanced optical and magnetic properties and discuss their potential as future MTW probes. European Commission - European Regional Development Fund Higher Education Authority Science Foundation Ireland Marie Curie Intra-European Fellowship
Keyword(s): Magnetic tweezers; Magnetic nanorods; Biophysical tools; Technical advances
Publication Date:
2017
Type: Journal article
Peer-Reviewed: Unknown
Language(s): English
Institution: University College Dublin
Publisher(s): Royal Society of Chemistry
First Indexed: 2019-05-11 06:16:49 Last Updated: 2019-05-11 06:16:49