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Frozen-thawed transfer cycles: are they comparable with fresh?
Mocanu, Edgar; Cottell, Evelyn; Waite, K; Hennelly, Bernadette; Collins, Claire; Harrison, Robert F
<p>The original article is available at <a href="http://archive.imj.ie//ViewArticleDetails.aspx?ArticleID=3219">imj.ie</a></p> <p>Cryopreservation of zygotes and subsequent thaw and transfer is an established ART treatment. We assessed if success rates frozen-thawed (day 2) zygotes are comparable with the outcome in fresh cycles of treatment. We performed a prospective follow-up and analysis of all frozen (FZT) and fresh cycles of treatment during a 12 months period. One hundred and nineteen patients in the frozen-thawed and 652 in the fresh group had a transfer. The overall thaw-survival rate was 71.7%. Clinical pregnancy rates per thaw and transfer were respectively 15.1% and 21% in the frozen and 29.1% (per transfer) in the fresh group. Implantation rates in fresh and frozen cycles were 16% and 12.3% respectively. The pregnancy loss rate was higher in the FZT group (29% vs. 18.3%). Cryopreservation of good quality zygotes, after fresh transfer offers optimal success rates in subsequent frozen treatment. It also encourages consideration of elective single zygote transfers.</p>
Keyword(s): Cryopreservation; Embryo Implantation; Embryo Transfer; Female; Fertilization in Vitro; Humans; Infertility; Pregnancy; Pregnancy Rate; Multiple; Reproductive Techniques; Assisted; Zygote; Medicine and Health Sciences; Obstetrics and Gynecology
Publication Date:
2008
Type: Journal article
Peer-Reviewed: Yes
Institution: Royal College of Surgeons in Ireland
Citation(s): Mocanu EV, Cottell E, Waite K, Hennelly B, Collins C, Harrison RF. Frozen-thawed transfer cycles: are they comparable with fresh? Irish Medical Journal. 2008;101(6):181-4.
Publisher(s): Irish Medical Organisation
File Format(s): application/pdf
Related Link(s): https://epubs.rcsi.ie/obsgynart/44
First Indexed: 2019-05-28 07:18:30 Last Updated: 2019-05-28 07:18:30