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Towards a comprehensive system for the recognition of double helical DNA : components for T and A
Dunne, Gavin Patrick
THESIS 5496 This thesis gives an account of the attempted synthesis of sequence selective double stranded DNA ligands. Two distinctive ligands types were envisaged, a pyrrolo[2', 3': 4, 5] thieno [2, 3-d]imidazole system (1.40 and 1.41) for the binding to the T-A/A-T base pairs, and an N-carbamoyl squaramide system (1.44) for binding the G-C/C-G base pairs.
Keyword(s): Chemistry, Ph.D.; Ph.D. Trinity College Dublin
Publication Date:
2000
Type: Doctoral thesis
Peer-Reviewed: Unknown
Language(s): English
Institution: Trinity College Dublin
Citation(s): Gavin Patrick Dunne, 'Towards a comprehensive system for the recognition of double helical DNA : components for T and A', [thesis], Trinity College (Dublin, Ireland). School of Chemistry, 2000, pp 198
Publisher(s): Trinity College (Dublin, Ireland). School of Chemistry
Supervisor(s): Davis, Tony
First Indexed: 2019-07-27 06:11:34 Last Updated: 2019-07-27 06:11:34