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Current Search:	'Cancer' in all fields;

Displaying Results 76 - 100 of 3133 on page 4 of 126

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Cancer projections for Ireland 2015-2040 (2014)

National Cancer Registry

Lenus

Report

unknown

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'Pragmatic randomized controlled trial of individually prescribed exercise versus usual care in a heterogeneous cancer survivor population': a feasibility study PEACH trial: prescribed exercise after chemotherapy. (2010)

WALSH, JULIE; HUSSEY, JULIETTE; GUINAN, EMER; O'DONNELL, DEARBHAILE

Trinity College Dublin

Journal article

peer-reviewed

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Melanoma-associated antigen family protein-D4: clinical significance and functional relevance in breast cancer (2010)

O'Driscoll, Lorraine

Trinity College Dublin

Conference item

peer-reviewed

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Long-term activation of the pro-coagulant response after neoadjuvant chemoradiation and major cancer surgery. (2010)

PIDGEON, GRAHAM; REYNOLDS, JOHN; MAHER, STEPHEN; WHITE, BARRY; O'DONNELL, JAMES

Trinity College Dublin

Journal article

peer-reviewed

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Trends and Patterns in Cancer Mortality in Northern Ireland (2010)

Donnelly, D.W.; Gavin, A.T.

Trinity College Dublin

Journal article

unknown

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Platelet Adhesion and Degranulation Induce Pro-Survival and Pro-Angiogenic Signalling in Ovarian Cancer Cells (2011)

SMYTH, PAUL; O'LEARY, JOHN; O'TOOLE, SHARON; SPILLANE, CATHY; MARTIN, CARA; G...

Platelet Adhesion and Degranulation Induce Pro-Survival and Pro-Angiogenic Signalling in Ovarian Cancer Cells (2011)

SMYTH, PAUL; O'LEARY, JOHN; O'TOOLE, SHARON; SPILLANE, CATHY; MARTIN, CARA; GALLAGHER, MICHAEL; NORRIS, LUCY; CONLON, NIAMH; MCEVOY, LYNDA MARIE; FFRENCH, GEORGE BRENDAN; STORDAL, BRITTA; KEEGAN, HELEN; FINN, STEPHEN; MCENEANEY, VICTORIA; SHEILS, ORLA; CROWLEY, DARRAGH

Abstract:

Thrombosis is common in ovarian cancer. However, the interaction of platelets with ovarian cancer cells has not been critically examined. To address this, we investigated platelet interactions in a range of ovarian cancer cell lines with different metastatic potentials [HIO-80, 59M, SK-OV-3, A2780, A2780cis]. Platelets adhered to ovarian cancer cells with the most significant adhesion to the 59M cell line. Ovarian cancer cells induced platelet activation [P-selectin expression] in a dose dependent manner, with the most significant activation seen in response to the 59M cell line. The platelet antagonists [cangrelor, MRS2179, and apyrase] inhibited 59M cell induced activation suggesting a P2Y12 and P2Y1 receptor mediated mechanism of platelet activation dependent on the release of ADP by 59M cells. A2780 and 59M cells potentiated PAR-1, PAR-4, and TxA2 receptor mediated platelet activation, but had no effect on ADP, epinephrine, or collagen induced activation. Analysis of gene expres...

Full-text link

http://hdl.handle.net/2262/60228

Trinity College Dublin

Journal article

peer-reviewed

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THE EMT-ACTIVATOR ZEB1 IS UNRELATED TO PLATINUM DRUG RESISTANCE IN OVARIAN CANCER BUT PREDICTIVE OF SURVIVAL (2014)

STORDAL, BRITTA KRISTINA

Trinity College Dublin

Conference item

non-peer-reviewed

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Erlotinib or gefitinib for the treatment of relapsed platinum pretreated non-small cell lung cancer and ovarian cancer: a systematic review. (2011)

STORDAL, BRITTA KRISTINA

Trinity College Dublin

Journal article

peer-reviewed

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Novel Microtubule targetting agents, pyrrolo-1,5,benzoxazepines induce apoptosis in multi-drug-resistant cancer cells (2010)

LLOYD, DAVID; ZISTERER, DANIELA; WILLIAMS, DAVID; FAYNE, DARREN

Trinity College Dublin

Journal article

peer-reviewed

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The MyD88+ Phenotype Is an Adverse Prognostic Factor in Epithelial Ovarian Cancer. (2014)

O'TOOLE, SHARON; O'NEILL, LUKE; GLEESON, NOREEN; O'BYRNE, KEN; O'LE...

Trinity College Dublin

Journal article

peer-reviewed

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RanGTPase: A Candidate for Myc-Mediated Cancer Progression (2013)

O'BYRNE, KEN

Trinity College Dublin

Journal article

peer-reviewed

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The presentation of metabolic dysfunction and the relationship with energy output in breast cancer survivors: a cross-sectional study. (2013)

HUSSEY, JULIETTE; KENNEDY, MICHAEL

Trinity College Dublin

Journal article

peer-reviewed

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A cohort study of metformin exposure and survival in patients with stage I-III colorectal cancer (2013)

BENNETT, KATHLEEN

Trinity College Dublin

Journal article

peer-reviewed

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Lipid Rafts as Master Regulators of Breast Cancer Cell Function (2011)

Babina, Irina S; Donatello, Simona; Nabi, Ivan R; Hopkins, Ann M

Royal College of Surgeons in Ireland

Book chapter

peer-reviewed

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Investigating novel mechanisms of metastasis in endocrine resistant breast cancer. (2014)

Bolger, Jarlath

Royal College of Surgeons in Ireland

Doctoral thesis

non-peer-reviewed

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SPINK1 protein expression and prostate cancer progression. (2014)

Finn, Stephen; Flavin, Richard

Trinity College Dublin

Journal article

peer-reviewed

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Symptoms and problem clusters in cancer and non cancer patients in specialized palliative care - is there a difference? (2014)

WALSH, THOMAS

Trinity College Dublin

Journal article

peer-reviewed

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JNK regulates Fas receptor mediated apoptosis in prostate cancer cell lines (2003)

Curtin, James

University College Cork

Doctoral thesis

non-peer-reviewed

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MiR-193b promotes autophagy and non-apoptotic cell death in oesophageal cancer cells (2016)

Nyhan, Michelle J.; O'Donovan, Tracey R.; Boersma, Antonius W. M.; Wiemer, Erik A....

University College Cork

Journal article

peer-reviewed

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Oral cancer incidence and survival rates in the Republic of Ireland, 1994-2009. (2016)

Ali, Hala; Sinnott, Sarah-Jo; Corcoran, Paul; Deady, Sandra; Sharp, Linda; Kabir, Zubair

Lenus

Journal article

unknown

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Anti-cancer effects of baicalein in non-small cell lung cancer in-vitro and in-vivo (2016)

Pidgeon, Graham; Lysaght, Joanne; O'Byrne, Ken; Gately, Kathy

Trinity College Dublin

Journal article

peer-reviewed

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Men's information-seeking behavior regarding cancer risk and screening: A meta-narrative systematic review (2017)

Saab, Mohamad M.; Reidy, Mary; Hegarty, Josephine; O'Mahony, Máirín; Murphy, Mike;...

University College Cork

Journal article

peer-reviewed

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Investigation into mechanisms of metastasis in breast cancer and pancreatic cancer (2017)

Moore, Gemma

Dublin City University

Other

unknown

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Exploring breast cancer and screening awareness among Irish women with intellectual disabilities (2018)

Reidy, Mary; Denieffe, Suzanne; Foran, Sinéad

University College Cork

Journal article

peer-reviewed

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Bronchoscopy in the investigation of outpatients with hemoptysis at a lung cancer clinic (2018)

Arooj, Parniya; Bredin, Emily; Henry, Michael T.; Khan, Kashif A.; Plant, Barry J.; Mur...

University College Cork

Journal article

peer-reviewed

Displaying Results 76 - 100 of 3133 on page 4 of 126

NUI Galway

Dublin City University

University College Cork

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University College Dublin

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Mary Immaculate College

Dublin Institute of Technology

Lenus

Dundalk Institute of Technology

Marine Institute

Teagasc

All Ireland Public Health Repository

Royal College of Surgeons in Ireland

IUA

HEA

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