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Displaying Results 201 - 225 of 2030 on page 9 of 82

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Assessment of methods for amino acid matrix selection and their use on empirical data shows that ad hoc assumptions for choice of matrix are not justified (2006)

Keane, Thomas; Creevey, Christopher; Pentony, Melissa; Naughton, Thomas J.; McInerney, ...

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The Opisthokonta and the Ecdysozoa May Not Be Clades: Stronger Support for the Grouping of Plant and Animal than for Animal and Fungi and Stronger Support for the Coelomata than Ecdysozoa (2005)

Philip, Gayle K.; Creevey, Christopher J.; McInerney, James O.

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Genome Phylogenies Indicate a Meaningful a-Proteobacterial Phylogeny and Support a Grouping of the Mitochondria with the Rickettsiales (2006)

Fitzpatrick, David A.; Creevey, Christopher J.; McInerney, James O.

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An Insight into the Impact of Arable Farming on Irish Biodiversity: A Scarcity of Studies Hinders a Rigorous Assessment (2008)

O'Brien, Martin; Spillane, Charles; Meade, Conor; Mullins, Ewen

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The anhydrobiotic potential and molecular phylogenetics of species and strains of Panagrolaimus (Nematoda, Panagrolaimidae) (2005)

Shannon, Adam J.; Browne, John A.; Boyd, Jacqueline; Fitzpatrick, David A.; Burnell, Ann

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Does a tree-like phylogeny only exist at the tips in the prokaryotes? (2004)

Creevey, Christopher J.; Fitzpatrick, David A.; Philip, Gayle K.; Kinsella, Rhoda J.; O...

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Some Desiderata for Liberal Supertrees (2004)

Wilkinson, Mark; Thorley, Joseph L.; Pisani, Davide; Lapointe, Francois-Joseph; McInern...

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Identification, cloning, and functional expression of three glutathione transferase genes from Aspergillus fumigatus (2005)

Burns, Claire; Geraghty, Rachel; Neville, Claire; Murphy, Alan; Kavanagh, Kevin; Doyle,...

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Heterorhabditis, Steinernema and their bacterial symbionts - lethal pathogens of insects (2000)

Burnell, Ann; Stock, S. Patricia

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Transition from Natively Unfolded to Folded State Induced by Desiccation in an Anhydrobiotic Nematode Protein (2003)

Goyal, Kshamata; Tisi, Laurence; Basran, Amrik; Browne, John; Burnell, Ann; Zurdo, Jesu...

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The Velvet Family of Fungal Regulators Contains a DNA-Binding Domain Structurally Similar to NF-kB (2013)

Ahmed, Yasar Luqman; Gerke, Jennifer; Park, Hee-Soo; Bayram, Ozgur; Neumann, Piotr; Ni,...

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The tree of genomes: An empirical comparison of genome-phylogeny reconstruction methods (2008)

McCann, Angela; Cotton, James A.; McInerney, James O.

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Molecular basis for the specification of floral organs by APETALA3 and PISTILLATA (2012)

Wuest, Samuel E.; Ó'Maoiléidigh, Diarmuid S.; Rae, Liina; Kwasniewska, Kamila; Rag...

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Deletion and Allelic Exchange of the Aspergillus fumigatus veA Locus via a Novel Recyclable Marker Module (2005)

Krappman, Sven; Bayram, Ozgur; Braus, Gerhard H.

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A Delineation of Mesenchymal Stromal Cell Therapeutic Action in New Models of Acute and Chronic Graft versus Host Disease (2015)

Healy, Marc E.

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Phylogenetic-Signal Dissection of Nuclear Housekeeping Genes Supports the Paraphyly of Sponges and the Monophyly of Eumetazoa (2009)

Sperling, Erik A.; Peterson, Devin J.; Pisani, Davide

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Polyphenism in social insects: insights from a transcriptome-wide analysis of gene expression in the life stages of the key pollinator, Bombus terrestris (2011)

Colgan, Thomas J.; Carolan, James C.; Bridgett, Stephen J.; Sumner, Seirian; Blaxter, M...

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NFκB2 p52 has a role in antiviral immunity through IKKε -dependent induction of Sp1 and IL-15 (2013)

Doyle, Sarah L.; Shirey, Kari Ann; McGettrick, Anne F.; Kenny, Elaine F.; Carpenter, Su...

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Expression profiling and cross-species RNA interference (RNAi) of desiccation-induced transcripts in the anhydrobiotic nematode Aphelenchus avenae (2010)

Reardon, Wesley; Chakrabortee, Sohini; Pereira, Tiago Campos; Tyson, Trevor; Banton, Ma...

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Using Steered Molecular Dynamics to Predict and Assess Hsp70 Substrate-Binding Domain Mutants that Alter Prion Propagation (2013)

Xu, Linan; Hasin, Naushaba; Shen, Manli; He, Jianwei; Xue, Youlin; Zhou, Xiaohong; Perr...

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Review: Comparison's Chimeras: Sandra Bamford. Biology Unmoored: Melanesian Reflections on Life and Biotechnology. Berkeley: University of California Press, 2007. 230 pp. (2008)

Strong, Thomas

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The Synthetic Cannabinoid R(+)WIN55,212-2 Augments Interferon-β Expression via Peroxisome Proliferator-activated Receptor-α (2012)

Downer, Eric J.; Clifford, Eileen; Amu, Sylvie; Fallon, Padraic G.; Moynagh, Paul N.

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Identification of the Synthetic Cannabinoid R()WIN55,212-2 as a Novel Regulator of IFN Regulatory Factor 3 Activation and IFN- Expression (2011)

Downer, Eric J.; Clifford, Eileen; Gran, Bruno; Hendrik, J. Nel; Fallon, Padraig G.; Mo...

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Genome of Acanthamoeba castellanii highlights extensive lateral gene transfer and early evolution of tyrosine kinase signaling (2013)

Clarke, Michael; Lohan, Amanda; Liu, Bernard; Lagkouvardos, Ilias; Roy, Scott; Zafar, N...

Genome of Acanthamoeba castellanii highlights extensive lateral gene transfer and early evolution of tyrosine kinase signaling (2013)

Clarke, Michael; Lohan, Amanda; Liu, Bernard; Lagkouvardos, Ilias; Roy, Scott; Zafar, Nikhat; Bertelli, Claire; Schilde, Christina; Kianianmomeni, Arash; Burglin, Thomas R.; Frech, Christian; Turcotte, Bernard; Kopec, Klaus O.; Synnott, John M.; Choo, Caleb; Paponov, Ivan; Finkler, Aliza; Soon Heng Tan, Chris; Hutchins, Andrew P.; Weinmeier, Thomas

Abstract:

Background The Amoebozoa constitute one of the primary divisio ns of eukaryotes encompassing taxa of both biomedic al and evolutionary importance, yet its genomic divers ity remains largely unsampled. Here we present an analysis of a whole genome assembly of Acanthamoeba castellanii ( Ac ) the first representative from a solitary free-living amoebozoan. Results Ac encodes 15,455 compact intron rich genes a signifi cant number of which are predicted to have arisen through interkingdom lateral gene transfer (LGT). A majority of the LGT candidates have undergone a substantial degree of intronization and Ac appears to have incorporated them into established transcriptional programs. Ac manifests a complex signaling and cell communicati on repertoire including a complete tyrosine kinase signaling toolkit and a comparable diversity of predicted extracellular receptors to that found in the facultatively multicellular dictyostelids. An impor tant environmental host of a diverse range of bac...