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Displaying Results 126 - 150 of 7448 on page 6 of 298
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Tissue engineering scaled-up anatomically shaped osteochondral constructs for joint resurfacing
(2014)
Mesallati, Tariq
Tissue engineering scaled-up anatomically shaped osteochondral constructs for joint resurfacing
(2014)
Mesallati, Tariq
Abstract:
THESIS 10426
Partial and total joint replacements are the only surgical procedures currently available to treat articular cartilage degeneration associated with degenerative diseases such as osteoarthritis (OA). While these procedures are well established, they are not without limitations and failures are not uncommon. Joint replacement prostheses also have a finite lifespan making them unsuitable for the growing population of younger and more active patients requiring treatment for OA. In recent years there has been increased interest in the use of cell and tissue engineering based therapies for the treatment of focal cartilage defects. These therapies aim to regenerate or replace damaged tissues through a combination of cells, three-dimensional scaffolds and signalling molecules. While significant progress has been made in this field, realizing an efficacious therapeutic option for the treatment of OA remains elusive and is considered to be one of the greatest challenges in th...
http://hdl.handle.net/2262/80349
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Developments in global software engineering education
(2016)
Clear, Tony; Beecham, Sarah; Barr, John; Daniels, Mats; Oudshoorn, Michael; Noll, John
Developments in global software engineering education
(2016)
Clear, Tony; Beecham, Sarah; Barr, John; Daniels, Mats; Oudshoorn, Michael; Noll, John
Abstract:
An ITiCSE 2015 conference working group report has recently delivered a comprehensive systematic review of the literature addressing the challenges and solutions in teaching global software engineering courses. In this panel session, a group of authors of that report will review the findings, and present their own views on teaching such courses, the pros and cons and their own motivations and experiences, together with strategies that have proven effective. We argue that these courses are critical for preparing students for practice as software engineers in today's global settings, but they are certainly not for the faint-hearted. After the review and presentation of position statements by panelists there will be a question and answer session with the audience and a discussion elaborating on the next frontiers in research and practice for global software engineering education.
ACCEPTED
peer-reviewed
http://hdl.handle.net/10344/6009
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Continuous software engineering – a microservices architecture perspective
(2017)
O'Connor, Rory; Elger, Peter; Clarke, Paul
Continuous software engineering – a microservices architecture perspective
(2017)
O'Connor, Rory; Elger, Peter; Clarke, Paul
Abstract:
From its earliest days, software development has been beset with challenges in relation to timely delivery, appropriateness of features and quality of deliverables. Many advances in software development processes have helped to address these concerns. For example, agile software development has helped to deliver working software more frequently and capability maturity frameworks have brought about improved consistency in quality levels. However, the age-old challenge of better, cheaper, faster software has continued to beguile developers. In this paper, we discuss an emerging approach to software development, continuous software engineering (CSE), wherein software of operational quality may be delivered on a very frequent basis, up to many times in a given day. This approach employs a complex set of independent tools that together reduce the lead time in delivering commercial-grade software. Having examined the situational context of one industrial organisation applying CSE, we conc...
http://doras.dcu.ie/22111/
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3D Bioprinting of Developmentally Inspired Templates for Bone and Joint Regeneration
(2018)
3D Bioprinting of Developmentally Inspired Templates for Bone and Joint Regeneration
(2018)
Abstract:
There is an urgent need to develop alternatives to synthetic joint prosthesis to promote the regeneration of diseased osteoarthritic joints. Cell based therapies have shown promise for repairing cartilage and bone; however, existing approaches are designed to repair small focal defects, and are not suitable for treating large injuries or for regenerating osteoarthritic joints. The objective of this thesis was to bioprint cell laden constructs capable of recapitulating key aspects of limb development as implants for large bone defect healing and joint regeneration. To this end, a novel biofabrication strategy for engineering whole bone organs was first developed by bioprinting hypertrophic cartilage templates with the capacity to undergo endochondral ossification following implantation in vivo. These soft cartilaginous templates could be mechanically reinforced with a network of co-printed polycaprolactone (PCL) microfibers, resulting in a dramatic increase in construct compressive ...
http://hdl.handle.net/2262/82727
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Finite element assisted prediction of ductile fracture in sheet bulging of magnesium alloys
(2008)
Hunt, David
Finite element assisted prediction of ductile fracture in sheet bulging of magnesium alloys
(2008)
Hunt, David
Abstract:
There is currently a growing demand for energy efficiency, particularly in reducing the rate of oil consumption. One solution in this area is for the aerospace and automotive industries to produce lighter vehicles that are more fuel efficient. Magnesium alloys provide that solution as they have a high strength to weight ratio and can contribute to reducing the overall weight of the vehicle. Over the past few years many researchers have tried shaping these alloys using various forming techniques. These studies have shown however, that the formability of these alloys is very difficult to predict. The material properties of magnesium alloys would suggest that they are ideal for sheet metal forming, yet their formability is still inferior to many other alloys used in sheet metal forming. In order to overcome this unpredictability in shaping Mg alloys it is necessary to introduce a range of failure that will predict fracture over a range of draw depths rather than a single depth. It is d...
http://doras.dcu.ie/571/
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Production of hard tissue scaffolds using three-dimensional printing method
(2009)
Szűcs, Tamás D.
Production of hard tissue scaffolds using three-dimensional printing method
(2009)
Szűcs, Tamás D.
Abstract:
Synthesised bone replacement scaffolds provide the possibility to individually tailor properties, overcome limited donor availability and improve osteointegration. The aim of bone tissue engineering is to provide solutions to these problems by making available high quality transplants that can be supplied in larger quantities. In these applications both the internal and external geometry of the scaffold are very important since they have significant effect on mechanical properties, permeability and cell proliferation. Rapid Prototyping technologies allow the use of customised materials with predetermined and optimised geometries to be fabricated with good accuracy. This work investigates the ability of the 3D printing technology to manufacture intricate bone scaffold geometries from biocompatible calcium phosphate based materials. Initial investigations with the proprietary materials showed that predicted directional mechanical behaviour can be realised. Practical measurements inves...
http://doras.dcu.ie/2373/
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On searching relevant studies in software engineering
(2010)
Zhang, He; Ali Babar, Muhammad
On searching relevant studies in software engineering
(2010)
Zhang, He; Ali Babar, Muhammad
Abstract:
BACKGROUND: Systematic Literature Review (SLR) has become an important research methodology in software engineering since 2004. One critical step in applying this methodology is to design and execute appropriate and effective search strategy. This is quite time consuming and error-prone step, which needs to be carefully planned and implemented. There is an apparent need of a systematic approach to designing, executing, and evaluating a suitable search strategy for optimally retrieving the target literature from digital libraries. OBJECTIVE: The main objective of the research reported in this paper is to improve the search step of doing SLRs in SE by devising and evaluating systematic and practical approaches to identifying relevant studies in SE. OUTCOMES: We have systematically selected and analytically studied a large number of papers to understand the state-of-the-practice of search strategies in EBSE. Having identified the limitations of the current ad-hoc nature of search strat...
http://hdl.handle.net/10344/730
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Design and Validation of a Force Measurement System for the Analysis of Airfoil Lift and Drag Characteristics
(2010)
Manning, Niall
Design and Validation of a Force Measurement System for the Analysis of Airfoil Lift and Drag Characteristics
(2010)
Manning, Niall
Abstract:
One of the aims of this research was to reduce the flow separation and therefore the pressure drag generated by a wing section, through the adding of surface modifications. The modifications consisted of roughening the surface of polystyrene airfoils using a sand blasting technique, which resulted in a dimpled surface. This idea originated from the design of a golf ball, as the dimples are known to delay flow separation which allows the ball to travel further. In relation to wing design, there has been very little research available that either proved or dismissed the theory of using a roughened airfoil surface to reduce the pressure drag created by flow separation. Therefore three types of airfoils were tested, the NACA 0006, 0024 and 4424 profiles. Different levels of surface roughness, created by the dimples, were applied to various portions and sides of the airfoils. These were in turn tested on the three airfoil types, including a series of tests with a split flap configuration...
http://doras.dcu.ie/15735/
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Chemical engineering in an unsustainable world: obligations and opportunities
(2009)
Byrne, Edmond P.; Fitzpatrick, John J.
Chemical engineering in an unsustainable world: obligations and opportunities
(2009)
Byrne, Edmond P.; Fitzpatrick, John J.
Abstract:
Human society faces a set of unprecedented challenges emanating from the unsustainable nature of the current societal model. The creation of a new sustainable societal construct is required, essentially adopting a needs based approach over one based on ever increasing consumption. Failure to achieve this will result in the widespread destruction of our increasingly stressed environment followed quickly by inevitable collapse of society as we know it, both socially and economically. Technology alone is insufficient to meet the challenges at hand; ecological, social and economic considerations must be incorporated through a multi-faceted and multi-disciplinary approach. Because chemical engineers possess a core set of threshold concepts which are central to a sustainable society, and because engineers will ultimately help design any new society, they bear a moral and ethical responsibility to play an active and indeed central role in its development. A new engineering paradigm is req...
http://hdl.handle.net/10468/344
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Multi-grounded action research in method engineering: the MMC case
(2007)
Karlsson, Fredrik; Agerfalk, Par J.
Multi-grounded action research in method engineering: the MMC case
(2007)
Karlsson, Fredrik; Agerfalk, Par J.
Abstract:
There appears to be two schools of information systems development methods research that largely pursue their own agendas without many cross-references, On the one hand there is the method engineering research and on the other hand there is the method-in-action research, There seems to be much to be gained from integrating these two schools, developing knowledge that both has the formality (rigor) and reflects its enactment in practice, To achieve this, the research approach adopted has to embrace this duality, In this paper we explore how multi-grounded action research (MGAR) can contribute to achieving this aim, MGAR has been used in the development of a method for method configuration, a research product that integrates the strengths of both schools.
http://hdl.handle.net/10344/2286
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Modularization constructs in method engineering: towards common ground?
(2007)
Agerfalk, Par J.; Brinkkemper, Sjaak; Henderson-Sellers, Brian; Karlsson, Fredrik; Kell...
Modularization constructs in method engineering: towards common ground?
(2007)
Agerfalk, Par J.; Brinkkemper, Sjaak; Henderson-Sellers, Brian; Karlsson, Fredrik; Kelly, Steven; Ralyte, Jolita
Abstract:
Although the Method Engineering (ME) research community has reached considerable maturity, it has not yet been able to agree on the granularity and definition of the configurable parts of methods. This state of affairs is causing unnecessary confusion, especially with an ever increasing number of people contributing to ME research. There are several competing notions around, most significantly 'method fragments' and 'method chunks', but also 'method components' and 'process components' are used in some quarters and have also been widely published. Sometimes these terms are used interchangeably, but there appears to be important semantic and pragmatic differences. If the differences are unimportant, we should be able to come to an agreement on what construct to promote. Alternatively, the different constructs may serve different purposes and there is a need for them to coexist. If this is the case, it should be possible to pinpoint exactly how ...
http://hdl.handle.net/10344/2284
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Development of a laser based surface profilometer using the principle of optical triangulation
(2005)
Collins, David Andrew
Development of a laser based surface profilometer using the principle of optical triangulation
(2005)
Collins, David Andrew
Abstract:
The metrology industry is constantly looking for new ways to accurately and quickly inspect and digitise surface topographies including the calculation o f surface roughness parameters and generating point clouds (a collection o f 3-dimensional points which describe a surface or surfaces) for modelling or reverse engineering purposes. Many types o f profllometer systems currently exist and the past decade has seen the rise in popularity o f optical based systems, however most optical profilometers are expensive to purchase and to maintain. The development o f optical profilometers can also be exceptionally complex depending on the type o f system and its fragility may not make it suitable for m ost workshop or factory floor applications. This project covers the development of a profllometer using the principle of optical triangulation. The developed system has a scanning table area of 200 by 120 millimetres and a vertical measurement range of five millimetres. The position o f the ...
http://doras.dcu.ie/17264/
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Collaboration, conflict and control: report on the 4th workshop on open source software engineering
(2005)
Feller, Joseph; Fitzgerald, Brian; Hissam, Scott; Lakhani, Karim
Collaboration, conflict and control: report on the 4th workshop on open source software engineering
(2005)
Feller, Joseph; Fitzgerald, Brian; Hissam, Scott; Lakhani, Karim
Abstract:
Building on the success of the first three workshops in the series, which were held at ICSE 2001 (Toronto), ICSE 2002 (Orlando) and ICSE 2003 (Portland), the 4th Workshop on Open Source Software Engineering, ("Collaboration, Conflict and Control") brought together researchers and practitioners for the purpose of discussing the platforms and tools, techniques and processes, and the organizational structures that are used to support and sustain communication, collaboration and conflict resolution within and between open source software communities.
http://hdl.handle.net/10344/2596
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Open source software development process for the development of open source e-learning systems
(2013)
Krishnamurthy, Aarthy
Open source software development process for the development of open source e-learning systems
(2013)
Krishnamurthy, Aarthy
Abstract:
Over the last decade, numerous educational institutions and corporate world have employed various kinds of e-learning software solutions. One of the major components of end-to-end e-learning solution is the learning management system (LMS). These LMS are either developed as open source software (OSS) or close source software (CSS) product. In this regard, CSS for e-learning systems has a major drawback of being expensive and this hinders its widespread use. On the other hand, OSS is virtually free and not restricted by the licensing costs. The benefits of OSS can be completely realized only if there is an effective contribution from OSS community towards its development. It is clear from the literature that the OSS development community does not follow an explicitly defined and documented software development process. This in turn results in lack of detailed information in the literature about the problems arising due to the absence of a defined process. Nevertheless, some of the m...
http://doras.dcu.ie/17642/
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Engineering automated systems for pharmaceutical manufacturing: quality, regulations and business performance
(2006)
Meagher, Diarmuid P.
Engineering automated systems for pharmaceutical manufacturing: quality, regulations and business performance
(2006)
Meagher, Diarmuid P.
Abstract:
The pharmaceutical sector is very heavily regulated Drug safety regulations form one of the pillars of this regulation. The manufacture of pharmaceuticals is carried out in an environment of onerous regulatory requirements, often from several national and international regulatory bodies. The quality systems operated by drug manufacturers and their regulatory practices have an important impact on product quality. The quality and regulatory requirements apply not only to handling of the medicinal products, but also to the physical and electronic systems used in the manufacture of those products, and extend to automated systems used to support quality assurance operations. Design, development, building and support of such systems are ultimately the responsibility of the drug manufacturer. The quality and regulatory requirements for automated systems are passed down the supply chain to suppliers. In the last two decades of the 20th century there has been a proliferation in the use of co...
http://doras.dcu.ie/18079/
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Physiological system modelling
(2003)
Parthasarathy, Sekar
Physiological system modelling
(2003)
Parthasarathy, Sekar
Abstract:
Computer graphics has a major impact in our day-to-day life. It is used in diverse areas such as displaying the results of engineering and scientific computations and visualization, producing television commercials and feature films, simulation and analysis of real world problems, computer aided design, graphical user interfaces that increases the communication bandwidth between humans and machines, etc Scientific visualization is a well-established method for analysis of data, originating from scientific computations, simulations or measurements. The development and implementation of the 3Dgen software was developed by the author using OpenGL and C language was presented in this report 3Dgen was used to visualize threedimensional cylindrical models such as pipes and also for limited usage in virtual endoscopy. Using the developed software a model was created using the centreline data input by the user or from the output of some other program, stored in a normal text file. The model...
http://doras.dcu.ie/18152/
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Production of coated and free-standing engineering components using the HVOF (High Velocity Oxy-Fuel) process
(2003)
Stokes, Joseph
Production of coated and free-standing engineering components using the HVOF (High Velocity Oxy-Fuel) process
(2003)
Stokes, Joseph
Abstract:
The present study aims to establish the potential of producing various hard metal industrial thick components using the High Velocity Oxy-Fuel (HVOF) thermal spray process, rather than by sintering or casting techniques currently used. It is innovative in that generally research work earned out on this process focuses on coating technologies. In order to spray-form thick tungsten carbide cobalt (WC-Co) components, certain problems have to be overcome. More specifically these problems include minimizing residual stresses (which cause shape distortion in the components), therefore maintaining the integrity of the deposit on a microstructural scale. Residual stress arises during deposition and, in the present research, was reduced by limiting the rise and fluctuation of the deposition temperature. This was achieved by the utilization of a carbon dioxide cooling system and automated traverse movement of the spray gun, which together enabled continuous deposition at a steady temperature...
http://doras.dcu.ie/18232/
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Integrated computer aided design simulation and manufacture
(1989)
Diko, Faek
Integrated computer aided design simulation and manufacture
(1989)
Diko, Faek
Abstract:
Computer Aided Design (CAD) and Computer Aided Manufacture (CAM) have been investigated and developed since twenty years as standalone systems. A large number of very powerful but independent packages have been developed for Computer Aided Design,Aanlysis and Manufacture. However, in most cases these packages have poor facility for communicating with other packages. Recently attempts have been made to develop integrated CAD/CAM systems and many software companies are actively engaged in this field of engineering. In the present work an integrated system for Computer Aided Design, Analysis and Manufacture has been developed incorporating AutoCAD Draughting package, Finite Element Analysis software and NC machining software. In this system, the draughting and NC machining software are resident m a PC and the Finite Element and Mesh Generation programs are resident m the mainframe computer. Appropriate softwares have also been developed for effective communication between different p...
http://doras.dcu.ie/18503/
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The design of an aluminium alloy wheel using three dimensional finite element analysis and fatigue life prediction
(1996)
Doyle, Mary M.
The design of an aluminium alloy wheel using three dimensional finite element analysis and fatigue life prediction
(1996)
Doyle, Mary M.
Abstract:
Styling has always played a very important role in automobile design. This factor as well as the demands of new safety legislation in Europe and through out the world makes it a very competitive industry. This often leads to complex car designs which need to be produced and proof tested with a minimum lead time and expenditure. But these new designs and manufacturing technologies must be reliable, thus the automobile manufacturer is increasingly investigating and developing new design tools to help improve the quality of their products. Computer aided engineering helps reduce the time necessary to produce a new design. It also improves the quality of design. In this study computer aided design, finite element analysis and fatigue life prediction are the tools which have been used. The design of a cast aluminium alloy wheel has been optimised using the Finite Element technique. It simulates the behaviour of the wheel under it's working load conditions. IDEAS Master Series has b...
http://doras.dcu.ie/18532/
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An online learning environment to teach artificial neural networks
(1999)
Galvin, Gareth
An online learning environment to teach artificial neural networks
(1999)
Galvin, Gareth
Abstract:
This thesis presents a study to evaluate the benefits of the Internet as an environment for Computer Aided Learning (CAL). It comprises of research into, current and previous approaches to CAL, and presents an implementation of the authors own approach, with the MEng (Masters in Electronic Engineering) course of Artificial Neural Networks (ANN’s) as a template upon which to develop courseware. CAL strives to stimulate the user interactively so as to facilitate an optimum knowledge transfer between teacher and student. This project will show th a t the Internet offers such features as hypertext, graphics, sound and video, which when incorporated correctly can engage the student and provide a more intuitive learning experience. Artificial Neural Networks were chosen as a template subject because of its iterative nature which lends itself well to graphical analysis. This, combined with its computationally intensive algorithms, lends itself well to a CAL environment. An evaluation of...
http://doras.dcu.ie/18743/
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Automating the product derivation process in software product line engineering
(2013)
O'Leary, Pádraig; Botterweck, Goetz; Richardson, Ita
Automating the product derivation process in software product line engineering
(2013)
O'Leary, Pádraig; Botterweck, Goetz; Richardson, Ita
Abstract:
A variety of automated approaches for software product line engineering in general and product derivation in particular have been proposed. Unfortunately due to a range of reasons, many development organisations fail to get the maximum benefit from these approaches. Worse, the way many organisations use these approaches actually hampers effective product derivation. As a foundation for the successful adoption of automated approaches in product derivation, a better understanding of the underlying activities in industrial product derivation practices is required. By consolidating current knowledge from literature and industrial experience, we have developed a process framework that comprises important tasks, which product line stakeholders have to perform during product derivation. We outline how our framework can provide a link to automated approaches by providing product derivation context and facilitating tool support for the overall process.
http://hdl.handle.net/10344/3367
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Who are we doing global software engineering research for?
(2013)
Beecham, Sarah; O'Leary, Pádraig; Richardson, Ita; Baker, Sean; Noll, John
Who are we doing global software engineering research for?
(2013)
Beecham, Sarah; O'Leary, Pádraig; Richardson, Ita; Baker, Sean; Noll, John
Abstract:
Twelve years ago a group of practitioners and researchers came together to try to solve problems relating specifically to Global Software Engineering (GSE) practice. This paper aims to assess whether the many hundreds of GSE research papers written over this period have had an impact on practice. We conducted semi-structured interviews with senior managers and project managers from ten companies, four of which are large multinationals (three in Fortune 100); four are medium sized enterprises, and two are small startups. GSE research is perceived as useful by industry with all participants stating that studying the subject would improve GSE performance; but all were unanimous in saying they did not read articles on GSE. Practitioners go to books, blogs, colleagues, forums, experience reports of 1-2 pages in length, or depend on their own experience to solve problems in GSE. Controversially, many didn’t see GSE as separate from general project management. Practitioners don’t want fram...
http://hdl.handle.net/10344/3369
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The engineering, management, and philosophy of service-oriented information systems
(2009)
Mora, Manuel; Pinhanez, Claudio; O'Connor, Rory; Blake, Brian
The engineering, management, and philosophy of service-oriented information systems
(2009)
Mora, Manuel; Pinhanez, Claudio; O'Connor, Rory; Blake, Brian
Abstract:
In this special issue on “The Engineering, Management, and Philosophy of Service-Oriented Information Systems” for the International Journal of Information Systems and the Service Sector (IJISSS), are presented five high-quality research articles.
http://doras.dcu.ie/19773/
Marked
Mark
4th International workshop on product line approaches in software engineering
(2013)
Rubin, Julia; Pleuss, Andreas; Botterweck, Goetz; Weiss, David M
4th International workshop on product line approaches in software engineering
(2013)
Rubin, Julia; Pleuss, Andreas; Botterweck, Goetz; Weiss, David M
Abstract:
This paper summarizes PLEASE 2013, the fourth edition of the PLEASE workshop series. The main goal of PLEASE is to encourage and promote the adoption of Software Product Line Engineering. To this end, we aim at bringing together researchers and industrial practitioners involved in developing families of related products in order to (1) facilitate a dialogue between these two groups and (2) initiate and foster long-term collaborations.
http://hdl.handle.net/10344/3665
Marked
Mark
A framework for the provision of online discrete event simulation for operational decision support in complex manufacturing environments
(2012)
Salman, Mustafa Ramzi
A framework for the provision of online discrete event simulation for operational decision support in complex manufacturing environments
(2012)
Salman, Mustafa Ramzi
Abstract:
The engineering body of knowledge contains an array of methodologies and techniques to address the effectiveness and efficiency of operational activities within a manufacturing environment. One such example is simulation modelling, a powerful analytical tool that can potentially be valuable in assisting decision makers, managers and engineers to gauge improvement opportunities and achieve process advancements. However, the cost of ownership for simulation models is not insignificant even for large multinationals, this stems from the requirements for specialist skills in simulation software, model development, data mining and statistical analysis. Simulation projects typically require a large investment to develop and usually are used-once-and-thrown-away. To reuse the model, it would require repeating a large portion of the development cycle. In order for simulation modelling to achieve wider recognition as a decision support tool there is a necessity to reduce the cost of model mai...
http://doras.dcu.ie/17441/
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