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Displaying Results 5076 - 5100 of 5357 on page 204 of 215
Marked
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Anticholinergic and sedative drug burden in community-dwelling older people: a national database study.
(2018)
Byrne, Catherine; Walsh, Caroline; Cahir, Caitriona; Ryan, Cristín; Williams, David; Be...
Anticholinergic and sedative drug burden in community-dwelling older people: a national database study.
(2018)
Byrne, Catherine; Walsh, Caroline; Cahir, Caitriona; Ryan, Cristín; Williams, David; Bennett, Kathleen
Abstract:
<p>The original article is available at <a href="https://bmjopen.bmj.com/content/8/7/e022500.long">bmjopen.bmj.com</a></p>
<p><strong>OBJECTIVES:</strong> The Drug Burden Index (DBI) tool quantifies individual exposure to anticholinergic and sedative medications. The DBI has been internationally validated against adverse health outcomes in older people. DBI exposure has not been reported in the Irish older population. This study aimed to: (1) develop a list of drugs with clinically significant anticholinergic and/or sedative effects (DBI medications) relevant to Ireland; (2) examine, using the DBI formula, the prevalence of exposure to DBI medications in Irish older people and (3) explore patient factors associated DBI exposure.</p> <p><strong>DESIGN:</strong> A cross-sectional national pharmacy claims database study.</p> <p><strong>SETTING:</strong> Community setting using the Ge...
https://epubs.rcsi.ie/psycholart/139
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Effect of deinstitutionalisation on quality of life for adults with intellectual disabilities: a systematic review
(2019)
May, Peter; Mc Carron, Mary; O'Donovan, Mary-Ann; Normand, Charles; Murphy, Esther...
Effect of deinstitutionalisation on quality of life for adults with intellectual disabilities: a systematic review
(2019)
May, Peter; Mc Carron, Mary; O'Donovan, Mary-Ann; Normand, Charles; Murphy, Esther; Smith, Valerie
Abstract:
Objective: To review systematically the evidence on how deinstitutionalisation affects quality of life (QoL) for adults with intellectual disabilities. Design: Systematic review. Population: Adults (aged 18 years and over) with intellectual disabilities. Interventions: A move from residential to community setting. Primary and secondary outcome measures: Studies were eligible if evaluating effect on QoL or life quality, as defined by study authors. Search: We searched MEDLINE, PsycINFO, CENTRAL, CINAHL, EconLit, Embase and Scopus to September 2017 and supplemented this with grey literature searches. We assessed study quality using the Critical Appraisal Skills Programme suite of tools, excluding those judged to be of poor methodological quality. Results: Thirteen studies were included; eight quantitative studies, two qualitative, two mixed methods studies and one case study. There was substantial agreement across quantitative and qualitative studies that a move to community living wa...
http://hdl.handle.net/2262/86426
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The characterisation of genetic diversity of a collection of perennial ryegrass (Lolium perenne L.)
(2008)
McGrath, Sarah Katherine
The characterisation of genetic diversity of a collection of perennial ryegrass (Lolium perenne L.)
(2008)
McGrath, Sarah Katherine
Abstract:
THESIS 8698
Perennial ryegrass (Lolium perenne L.) is a member of the Poaceae family, is native to Europe, the Near East and North Africa and is grown in all the temperate climate areas of the world as a forage and turf grass. Due to its persistence, palatability and nutritive value for ruminants, it is a principal component of pastures, and the most important forage species in Ireland. The primary aim of this thesis was to characterise the level of diversity in a large genetic resource collection of L. perenne germplasm held at Teagasc, Oak Park. Molecular markers, both chloroplast and nuclear SSRs, biochemical characters (water soluble carbohydrate, crude protein, and dry matter), and morphological characters (vegetative and flowering) were used to characterise this diversity, as well as population differentiation, and geographic patterns. Levels of diversity in all systems were found to be high in this collection.
http://hdl.handle.net/2262/86495
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The biogeography and conservation biology of Spiranthes romanzoffiana Chamisso
(2008)
Lupton, Darach
The biogeography and conservation biology of Spiranthes romanzoffiana Chamisso
(2008)
Lupton, Darach
Abstract:
THESIS 8346
The aim of this research was to gather baseline data on Irish populations of Spiranthes romanzoffiana, a species with an uneven amphi-Atlantic distribution. The species is widespread in North America. In Europe, populations are confined to the west and north east of Ireland and to the Hebridean islands in western Scotland. S. romanzoffiana is protected in the Republic of Ireland by the Wildlife Act (1967), under the Flora Protection Order [SI 94 of 1999] and is an Irish Red List species. Four sample populations in the Republic of Ireland were studied to determine the ecology, population, reproductive and pollination biology of S. romanzoffiana. Threats to the species' persistence were assessed at each site. Amplified Fragment Length Polymorphism (AFLP) and chloroplast microsatellite markers were used to determine the level of genetic diversity and differentiation within and between Irish, Scottish and North American samples.
http://hdl.handle.net/2262/86452
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Mark
Ecology, epidemiology and evolution in a gut trypanosomatid parasite of bumble bees with multiple host species
(2007)
Ruiz-Gonz?lez, Mario Xavier
Ecology, epidemiology and evolution in a gut trypanosomatid parasite of bumble bees with multiple host species
(2007)
Ruiz-Gonz?lez, Mario Xavier
Abstract:
THESIS 8106
I have empirically explored the impact of different factors on the coevolution of a multihost-parasite system consisting of a gut trypanosomatid and its bumble bee host species assemblage. I have studied the potential impact of different factors on the epidemiology of the parasite, and thus, I have explored both the within host and among host species dynamics: host heterogeneity (host nutrition, host sex, host caste, host species), the potential for parasite intra- and inter-specific transmission, and the genetic structure of the parasite population at both geographical and temporal scales. While most of these factors have been previously suggested as determinant of the coevolutionary dynamics between host and parasites other factors were studied as a logical extension of some findings or because they are potentially important to further understand the evolution of this system. I found that: (i) the parasite has been forced to adopt a generalist strategy; (ii) the dr...
http://hdl.handle.net/2262/86604
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Computational study of the alpha1-Adrenoceptor subtypes and their ligands
(2008)
Matijssen, Berry
Computational study of the alpha1-Adrenoceptor subtypes and their ligands
(2008)
Matijssen, Berry
Abstract:
THESIS 8602
Adrenoceptors (AR) belong to the G-protein coupled receptor (GPCR) family. These receptors play an important role in regulating many processes in the body related to the central nervous system, vascular system and many others. The importance of these receptors as regulators can be further stressed as they are considered promising drug targets. Currently 40 % of all marketed drugs are targeted at GPCRs. The adrenoceptors can be subdivided into nine different classes of which the ?1-AR class consists of three subtypes (?14-AR, ?1B-AR and ?1D-AR). This ?1-AR class plays an important role in the condition known as benign prostatic hyperplasia (BPH). BPH affects 50% of men over 50 years old and with the aging of the population percentage, this percentage is expected to rise. BPH is manifested by the enlargem ent of prostate tissue that constrains the urethra Prostatic smooth muscle contraction occurs mainly via the ?1A-AR subtype. The effect of BPH is manifested through t...
http://hdl.handle.net/2262/86470
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Mark
The effectiveness of the proprioceptive neuromuscular facilitation method on gait parameters in patients with stroke: a systematic review
(2018)
Gunning, Emer; Uszynski, Marcin Kacper
The effectiveness of the proprioceptive neuromuscular facilitation method on gait parameters in patients with stroke: a systematic review
(2018)
Gunning, Emer; Uszynski, Marcin Kacper
Abstract:
The full text of this article will not be available in ULIR until the embargo expires on the 22/12/2019
Objective To review the current evidence for the effectiveness of proprioceptive neuromuscular facilitation (PNF) techniques on gait parameters in patients with stroke. Data Sources The electronic platforms of CINAHL, MEDLINE, PubMed, and the Physiotherapy Evidence Database were searched using the relevant search terms. Study Selection Intervention studies that had gait parameters as an outcome and in which PNF techniques were used in a poststroke population were reviewed. The studies were reviewed by both authors and a consensus was reached. The literature search identified 84 studies. Following screening, there were 5 studies that met the inclusion criteria for this review. Data Extraction Data were extracted from the studies by both authors and independently reviewed. Methodological quality was assessed with the Physiotherapy Evidence Database scale of randomized ...
http://hdl.handle.net/10344/7805
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Syzygium jambos(L.)Alston(Myrtaceae) control, conservation and restoration of the threatened native flora of Pitcairn Island, South Central Pacific
(2008)
Smyth, Noeleen
Syzygium jambos(L.)Alston(Myrtaceae) control, conservation and restoration of the threatened native flora of Pitcairn Island, South Central Pacific
(2008)
Smyth, Noeleen
Abstract:
THESIS 8508
To fully fulfil the many aspirations of plant conservation, a quantitative, practical and economic approach to the problems in hand must be taken. Modem conservation biology involves recovering lost habitat and thwarting exotic invaders, alongside single species conservation which requires some investigation into population viability and molecular genetics. In order to fulfil these aims for conservation efforts on Pitcairn Island, a logical approach was taken for this small island ecosystem, which can be used as a model for larger and more diverse islands, and fragmented landscapes on continents, which can be considered as "islands in a sea of land".
http://hdl.handle.net/2262/86624
Marked
Mark
TRPV4-mediates oscillatory fluid shear mechanotransduction in mesenchymal stem cells in part via the primary cilium
(2018)
Hoey, David
TRPV4-mediates oscillatory fluid shear mechanotransduction in mesenchymal stem cells in part via the primary cilium
(2018)
Hoey, David
Abstract:
Skeletal homeostasis requires the continued replenishment of the bone forming osteoblast from a mesenchymal stem cell (MSC) population, a process that has been shown to be mechanically regulated. However, the mechanisms by which a biophysical stimulus can induce a change in biochemical signaling, mechanotransduction, is poorly understood. As a precursor to loading-induced bone formation, deciphering the molecular mechanisms of MSC osteogenesis is a critical step in developing novel anabolic therapies. Therefore, in this study we characterize the expression of the mechanosensitive calcium channel Transient Receptor Potential subfamily V member 4 (TRPV4) in MSCs and demonstrate that TRPV4 localizes to areas of high strain, specifically the primary cilium. We demonstrate that TRPV4 is required for MSC mechanotransduction, mediating oscillatory fluid shear induced calcium signaling and early osteogenic gene expression. Furthermore, we demonstrate that TRPV4 can be activated pharmacologi...
http://hdl.handle.net/2262/86701
Marked
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Modeling the functional link between movement, feeding activity, and condition in a marine predator
(2018)
Pirotta, Enrico; Schwarz, Lisa K.; Costa, Daniel P.; Robinson, Patrick W.; New, Leslie
Modeling the functional link between movement, feeding activity, and condition in a marine predator
(2018)
Pirotta, Enrico; Schwarz, Lisa K.; Costa, Daniel P.; Robinson, Patrick W.; New, Leslie
Abstract:
The ability to quantify animals’ feeding activity and the resulting changes in their body condition as they move in the environment is fundamental to our understanding of a population’s ecology. We use satellite tracking data from northern elephant seals (Mirounga angustirostris), paired with simultaneous diving information, to develop a Bayesian state-space model that concurrently estimates an individual’s location, feeding activity, and changes in condition. The model identifies important foraging areas and times, the relative amount of feeding occurring therein, and thus the different behavioral strategies in which the seals engage. The fitness implications of these strategies can be assessed by looking at the resulting variation in individuals’ condition, which in turn affects the condition and survival of their offspring. Therefore, our results shed light on the processes affecting an individual’s decision-making as it moves and feeds in the environment. In addition, we demonst...
http://hdl.handle.net/10468/7855
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The associations between training load and baseline characteristics on musculoskeletal injury and pain in endurance sport populations: a systematic review.
(2018)
Johnston, Richard; Cahalan, Róisin Máire; O'Keeffe, Mary; O'Sullivan, Kieran;...
The associations between training load and baseline characteristics on musculoskeletal injury and pain in endurance sport populations: a systematic review.
(2018)
Johnston, Richard; Cahalan, Róisin Máire; O'Keeffe, Mary; O'Sullivan, Kieran; Comyns, Thomas M.
Abstract:
The full text of this article will not be available in ULIR until the embargo expires on the 14/03/2020
Objectives To determine the associations between training load, baseline characteristics (e.g. age or previous injury) and rate of musculoskeletal injury and/or pain specifically within an Endurance Sporting Population (ESP). Design Prospectively registered systematic review. Methods Eight electronic databases were searched by two independent reviewers. Studies were required to prospectively monitor both (i) training loads and (ii) musculoskeletal injury and/or pain for >3 months. Methodological quality and risk of bias were determined utilising the Critical Skills Appraisal Program (CASP). Reported effect sizes were categorised as small, medium or large. Results Twelve endurance sport studies were eligible (running, triathlon, rowing). Increased injury and/or pain risk was associated with: (i) high total training distances per week/month (medium effect size) (ii)...
http://hdl.handle.net/10344/7812
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An evaluation of prescribing trends and patterns of claims within the Preferred Drugs Initiative in Ireland (2011-2016): an interrupted time-series study.
(2018)
McDowell, Ronald; Bennett, Kathleen; Moriarty, Frank; Clarke, Sarah; Barry, Michael; Fa...
An evaluation of prescribing trends and patterns of claims within the Preferred Drugs Initiative in Ireland (2011-2016): an interrupted time-series study.
(2018)
McDowell, Ronald; Bennett, Kathleen; Moriarty, Frank; Clarke, Sarah; Barry, Michael; Fahey, Tom
Abstract:
<p>The original article is available at <a href="https://bmjopen.bmj.com/content/8/4/e019315.long">bmjopen.bmj.com</a></p>
<p><strong>OBJECTIVE:</strong> To examine the impact of the Preferred Drugs Initiative (PDI), an Irish health policy aimed at enhancing evidence-based cost-effective prescribing, on prescribing trends and the cost of prescription medicines across seven medication classes.</p> <p><strong>DESIGN:</strong> Retrospective repeated cross-sectional study spanning the years 2011</p> <p><strong>SETTING:</strong> Health Service Executive Primary Care Reimbursement Service pharmacy claims data for General Medical Services (GMS) patients, approximately 40% of the Irish population.</p> <p><strong>PARTICIPANTS:</strong> Adults aged ≥18 years between 2011 and 2016 are eligible for the GMS scheme.</p> <p><strong>PRIMARY AND SECONDARY ...
https://epubs.rcsi.ie/gpart/136
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"New Troy": the Irish at Oostende in the First Half of the Seventeenth Century
(2018)
Hazard, Benjamin (Benjamin James Joseph)
"New Troy": the Irish at Oostende in the First Half of the Seventeenth Century
(2018)
Hazard, Benjamin (Benjamin James Joseph)
Abstract:
Since the ‘drum and trumpet’ narratives of the nineteenth-century, the Irish presence in the armed forces of the Spanish Habsburgs has attracted historians’ interest. In recent decades, most notably since the work of Brendan Jennings OFM, this field of historical research has received increasing attention. Nevertheless, apart from isolated examples,3 no concerted effort has hitherto been made to substantiate the experiences of Irish exiles in specific centres of population abroad, such as the harbour towns of Galicia and Flanders. In part, this reflects the scale of religious and cultural upheaval in early-modern Europe where many Irish exiles moved from one theatre of war to another. Since war was an ever-present reality of life,4 Irish soldiers served in the armies of Spain, France, Sweden and elsewhere during the first half of the seventeenth century.
Louvain 400 Fellowship Mícheál Ó Cléirigh Institute
http://hdl.handle.net/10197/9207
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Notes on the Demography of the Famine in Ulster
(2017)
Ó Gráda, Cormac
Notes on the Demography of the Famine in Ulster
(2017)
Ó Gráda, Cormac
Abstract:
At what level of aggregation should the Famine be analysed? Some data are available only at a fairly aggregated level, while a small number are available down to townland level. Comparative analysis involves trade-offs between the level of aggregation and the choice of explanatory variables. While an artificial unit of analysis, the province, does have the charm of dividing the island into north, south, east and west, Ulster escaped the Famine more lightly than the other three provinces. But its impact, as reflected in population change between 1841 and 1851, was more uneven in Ulster than in any of the other three provinces.
http://hdl.handle.net/10197/8730
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Re-thinking the post-crash city: vacant space, temporary use and new urban imaginaries?
(2017)
Moore-Cherry, Niamh
Re-thinking the post-crash city: vacant space, temporary use and new urban imaginaries?
(2017)
Moore-Cherry, Niamh
Abstract:
Cities are at the forefront of some of the most profound social and environmental changes taking place globally. As centres of technological and economic development, hubs for international migrants and refugees, key focal points in geopolitical disputes and the home of growing proportions of the world’s population, cities are increasingly spaces where the stabilities and instabilities of the contemporary world are at their most intense. Yet, cities are also important actors, sustaining the mobility of people and ideas, and enabling inhabitants to make sense of, respond to, and imagine change within particular institutional and ideological frameworks. Imaginaries of the city, defined by the interactions between different social groups and sets of laws, values, institutions and symbols (Sartre, 1940) abound and this special issue tracks how these are evolving in the context of Dublin, Ireland in the period since the Global Financial Crisis (GFC).
http://hdl.handle.net/10197/8649
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A novel method of microsatellite genotyping-by-sequencing using individual combinatorial barcoding
(2017)
Vartia, Salla; Villanueva-Cañas, José L.; Finarelli, John A.; Farrell, Edward D.; Hughe...
A novel method of microsatellite genotyping-by-sequencing using individual combinatorial barcoding
(2017)
Vartia, Salla; Villanueva-Cañas, José L.; Finarelli, John A.; Farrell, Edward D.; Hughes, Graham M.; Carlsson, Jeanette E. L.; Carlsson, Jens; et al.
Abstract:
This study examines the potential of next-generation sequencing based 'genotyping-by-sequencing'(GBS) of microsatellite loci for rapid and cost-effective genotyping in large-scale population genetic studies. The recovery of individual genotypes from large sequence pools was achieved by PCR-incorporated combinatorial barcoding using universal primers. Three experimental conditions were employed to explore the possibility of using this approach with existing and novel multiplex marker panels and weighted amplicon mixture. The GBS approach was validated against microsatellite data generated by capillary electrophoresis. GBS allows access to the underlying nucleotide sequences that can reveal homoplasy, even in large datasets and facilitates cross laboratory transfer. GBS of microsatellites, using individual combinatorial barcoding, is potentially faster and cheaper than current microsatellite approaches and offers better and more data.
European Commission - European Regio...
http://hdl.handle.net/10197/8467
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Influence of fatigue on turning characteristics in those with chronic ankle instability
(2017)
Remus, Alexandria; Delahunt, Eamonn; Caulfield, Brian
Influence of fatigue on turning characteristics in those with chronic ankle instability
(2017)
Remus, Alexandria; Delahunt, Eamonn; Caulfield, Brian
Abstract:
6th International Ankle Symposium (IAS), Dublin, Ireland, 16-18 October 2015
Background: Ankle sprains are typically sustained during change of direction tasks and often occur during the latter thirds of both halves of matches. The effects of fatigue on turning kinematic characteristics has not been studied in a chronic ankle instability population.
http://hdl.handle.net/10197/8584
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Celtic phoenix or leprechaun economics? The politics of an FDI led growth model in Europe
(2017)
Regan, Aidan; Brazys, Samuel
Celtic phoenix or leprechaun economics? The politics of an FDI led growth model in Europe
(2017)
Regan, Aidan; Brazys, Samuel
Abstract:
In this paper we argue that Ireland’s post-crisis economic recovery in Europe was driven by foreign direct investment (FDI) from Silicon Valley, and whilst this growth model was made possible by Ireland’s low corporate tax rates, it was also a result of these firms using Ireland to directly access the European labour market. We evidence this contention via sectoral and geographic analyses while simultaneously showing that Irish fiscal policies have not redistributed gains from the recovery to the broader population. As a result, the economic recovery has been most actively felt by those in the FDI sectors, including foreign-national workers from the EU and beyond. We suggest that this experience indicates that Ireland’s FDI-led model of economic development has created clear winners and losers, with significant distributional implications. The FDI growth regime been made possible by inward migration and European integration, but given the unequal distribution of the economic benefit...
http://hdl.handle.net/10197/8479
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Motherhood in Ireland, Creation and Context
(2017)
Kennedy, Patricia
Motherhood in Ireland, Creation and Context
(2017)
Kennedy, Patricia
Abstract:
In this book I bring together creative and critical writing on motherhood in Ireland in an attempt to understand its complexity. I am conscious that motherhood has been used as a symbol in Ireland in political, cultural and social life. In the course of editing this book I met many men and women who told me that they did not feel qualified to write about motherhood, and some expressed a fear of speaking on the subject. This they all agreed was because they had not experienced physiological motherhood. I found this very disturbing, as it seemed to imply that a whole section of the population had been silenced.
http://hdl.handle.net/10197/9080
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Ageing and Irish Social Policy
(2017)
Quinn, Suzanne; Kennedy, Patricia
Ageing and Irish Social Policy
(2017)
Quinn, Suzanne; Kennedy, Patricia
Abstract:
Ageing and Social Policy in Ireland brings together the writings of specialists in a range of areas relevant to the situation of older people in Ireland. The overall subject of ageing and social policy is of current relevance and will remain so in the coming decades. This is because Ireland, like other European countries, is facing demographic changes and parallel policy challenges. The average life expectancy has increased quite dramatically in recent decades. The average life expectancy for a man in Ireland at age 66 is now 80 . 6 years while, on average, a woman at the same age will have a further 17 . 9 years to live. Social Inclusion: Building an Inclusive Society , the National Plan for Social Inclusion (Government of Ireland, 2002), outlines a vision for older people in which they are enabled to maintain their health and well-being, live active and full lives, indepen- dently and in their own homes and communities for as long as possible. It envisions older people participati...
http://hdl.handle.net/10197/9081
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A Genetic Algorithm for a Green Vehicle Routing Problem
(2017)
Oliveira, Paulo Roberto da Costa; Mauceri, Stefano; Carroll, Paula; Pallonetto, Fabiano
A Genetic Algorithm for a Green Vehicle Routing Problem
(2017)
Oliveira, Paulo Roberto da Costa; Mauceri, Stefano; Carroll, Paula; Pallonetto, Fabiano
Abstract:
International Network Optimization Conference 2017 (INOC 2017), Lisboa, Portugal, 26-28 February 2017
We propose a Genetic Algorithm (GA) to address a Green Vehicle Routing Problem (G-VRP). Unlike classic formulations of the VRP, this study aims to minimise the CO 2 emissions per route. The G-VRP is of interest to policy makers who wish to reduce greenhouse gas emissions. The GA is tested on a suite of benchmark, and real-world instances which include road speed and gradient data. Our solution ap- proach incorporates elements of local and population search heuristics. Solutions are compared with routes currently used by drivers in a courier company. Reductions in emissions are achieved without incurring additional operational costs.
http://hdl.handle.net/10197/8702
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Universal Design for Learning to support nursing students: Experiences in the Field
(2019)
Halligan, Philomena; Martyn, Katharine; Pace, Kerry; et al.
Universal Design for Learning to support nursing students: Experiences in the Field
(2019)
Halligan, Philomena; Martyn, Katharine; Pace, Kerry; et al.
Abstract:
Higher education institutions have an increasingly diverse student population and in response have developed a range of services to support students (HEFCE 2015). Therefore, there is increased pressure to embed most support within the general university provision. As a consequence, there is a resurgence of interest in the application of universal design principles in higher education to meet the needs of individual students (AHEAD 2017). As limited international literature is available about the use of Universal Design for Learning (UDL) in nurse education; this paper will explore the application of these principles to support nursing students who have additional needs, in particular, in the practice setting.
http://hdl.handle.net/10197/10154
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Universal Design for Curriculum Design: Case Studies from University College Dublin
(2019)
Universal Design for Curriculum Design: Case Studies from University College Dublin
(2019)
Abstract:
Universal Design is a principle-based approach to designing university teaching and learning to meet the learning needs of all students. This includes the needs articulated by the UCD students quoted here. Higher Education has become increasingly diverse, with a particularly rapid change in the last ten years. As we now strive to achieve widening participation of those students traditionally under-represented in Higher Education, and open our campuses to increasing numbers of international students, we must ensure that our teaching and learning develops in line with the student population. Universal Design (UD) offers us a framework that helps us to consider and embrace our diverse classrooms. While we may not all be experts in particular disability types, using the UD framework gives you the tools you need to take all learners in to consideration when planning and designing your curriculum.
http://hdl.handle.net/10197/9851
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Interaction techniques for older adults using touchscreen devices: a literature review from 2000 to 2013
(2019)
Motti, Lilian Genaro; Vigouroux, Nadine; Gorce, Philippe
Interaction techniques for older adults using touchscreen devices: a literature review from 2000 to 2013
(2019)
Motti, Lilian Genaro; Vigouroux, Nadine; Gorce, Philippe
Abstract:
Some remarkable advances in mobile technologies have been made on the past fifteen years, especially the adoption of direct input on the screen. Since aging is now a worldwide demographic phenomenon, several studies have been carried on to investigate and improve the interaction between older aged adults and these new technologies. These studies are important because mobile devices are often equipped with touchscreen and they can help to improve quality of life for older adults (health care, social life, serious games). Understanding interaction of this group of users with touchscreen can facilitate the adoption of interactive technologies and their future use by older populations. This literature review analyses thirty six studies that evaluated interaction techniques for older users using touchscreen devices. This review intends to 1) analyze the situation of thirty six studies (population, apparatus, tasks and interaction techniques) and 2) identify situations of use of touchscre...
http://hdl.handle.net/10197/10312
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Overnight auto-adjusting continuous airway pressure + standard care compared with standard care alone in the prevention of morbidity in sickle cell disease phase II (POMS2b): Study protocol for a randomised controlled trial
(2019)
Howard, Jo; Slee, April E.; Skene, Simon; Downes, Michelle; et al.
Overnight auto-adjusting continuous airway pressure + standard care compared with standard care alone in the prevention of morbidity in sickle cell disease phase II (POMS2b): Study protocol for a randomised controlled trial
(2019)
Howard, Jo; Slee, April E.; Skene, Simon; Downes, Michelle; et al.
Abstract:
Background: In addition to pain, sickle cell anaemia (HbSS) complications include neurocognitive difficulties in attention and processing speed associated with low daytime and night-time oxygen saturation compounded by obstructive sleep apnoea (OSA). In the general population OSA is treated with continuous positive airways pressure (CPAP). The aim of this single-blind, randomised, controlled phase II trial is to compare auto-adjusting CPAP (APAP) with standard care to standard care alone in individuals with HbSS to determine whether the intervention improves attention and processing speed, brain structure, pain and quality of life. Methods/Design: Eligibility criteria include: ability to provide informed consent; age>8years; diagnosis of HbSS; and mean overnight saturation of<90% for<30% of the night (i.e. not meeting current criteria for overnight oxygen therapy). Key exclusion criteria are: overnight respiratory support; respiratory or decompensated cardiac failure; chron...
http://hdl.handle.net/10197/10375
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