rian.ie - Results

A A A

Current Search:	'regulation' in all fields;

Displaying Results 1 - 25 of 3416 on page 1 of 137

Mark

Does corruption ease the burden of regulation? National and subnational evidence (2017)

Breen, Michael; Gillanders, Robert

Mark

Governance reform of German food safety regulation: Cosmetic or real? (2006)

Steiner, Bodo E.

Mark

Integrating cognitive, motivational, and emotional self-regulation in early stage entrepreneurs (2011)

O'Shea, Deirdre

Mark

Regulation and firm perception, eco-innovation and firm performance (2012)

Doran, Justin; Ryan, Geraldine

Mark

Economic regulation: recentralisation of power or improved quality of regulation? (2011)

Gorecki, Paul K.

Mark

Competition and Regulation in the Retail Pharmacy Market (2004)

Purcell, Declan

Mark

An economic analysis of the Public Transport Regulation Act, 2009 (2011)

Barrett, Sean D.

Mark

The 'Dance' of Kinship Care in England and Ireland: Navigating a course between regulation and relationships (2013)

GILLIGAN, ROBERT

Mark

Corruption, institutions and regulation (2012)

Breen, Michael; Gillanders, Robert

Mark

Power in The Wind (2018)

O'CONNOR, MICHAEL MARTIN

Mark

Learning to change: the role of organisational capabilities in industry response to environmental regulation. (2002)

Hilliard, Rachel

Mark

NF-κB regulation: The nuclear response (2009)

GRAY, STEVEN; LAWLESS, MATTHEW; KELLEHER, DERMOT; MANKAN, ARUN KUMAR; MCMANUS, ROSS

Mark

The Regulation of Armed Non-State Actors: Promoting the Application of the Laws of War to Conflicts Involving National Liberation Movements (2009)

Higgins, Noelle

Mark

Information and communication technology for environmental regulation: developing a research agenda (2013)

Khoo, Su-Ming; Hickey, Kieran R.

Mark

The aliphatic amidase AmiE is involved in regulation of Pseudomonas aeruginosa virulence (2017)

Clamens, Thomas; Rosay, Thibaut; Crépin, Alexandre; Grandjean, Teddy; Kentache, Takfari...

The aliphatic amidase AmiE is involved in regulation of Pseudomonas aeruginosa virulence (2017)

Clamens, Thomas; Rosay, Thibaut; Crépin, Alexandre; Grandjean, Teddy; Kentache, Takfarinas; Hardouin, Julie; Bortolotti, Perrine; Neidig, Anke; Mooij, Marlies J.; Hillion, Mélanie; Vieillard, Julien; Cosette, Pascal; Overhage, Joerg; O'Gara, Fergal; Bouffartigues, Emeline; Dufour, Alain; Chevalier, Sylvie; Guery, Benoit; Cornelis, Pierre; Feuilloley, Marc G. J.

Abstract:

We have previously shown that the eukaryotic C-type natriuretic peptide hormone (CNP) regulates Pseudomonas aeruginosa virulence and biofilm formation after binding on the AmiC sensor, triggering the amiE transcription. Herein, the involvement of the aliphatic amidase AmiE in P. aeruginosa virulence regulation has been investigated. The proteome analysis of an AmiE over-producing strain (AmiE+) revealed an expression change for 138 proteins, including some that are involved in motility, synthesis of quorum sensing compounds and virulence regulation. We observed that the AmiE+ strain produced less biofilm compared to the wild type, and over-produced rhamnolipids. In the same line, AmiE is involved in P. aeruginosa motilities (swarming and twitching) and production of the quorum sensing molecules N-acyl homoserine lactones and Pseudomonas Quinolone Signal (PQS). We observed that AmiE overproduction reduced levels of HCN and pyocyanin causing a decreased virulence in different hosts (i...