rian.ie - Results

A A A

Current Search:	'regulation' in all fields;

Displaying Results 76 - 100 of 3104 on page 4 of 125

Mark

The tenement homes of Dublin: their condition and regulation (1899)

Eason, Charles

Trinity College Dublin

Journal article

peer-reviewed

Mark

The Alert Programme for Self Regulation - an evaluation of a group based intervention for children attending a child and adolescent mental health clinic (2011)

CREMIN, KATIE

Trinity College Dublin

Other

peer-reviewed

Mark

Experimental validation of CFD modelling for thermal regulation o photovoltaic panels using phase change material (2011)

Sarwar, SARAH; MC CORMACK; Huang; Norton

Trinity College Dublin

Conference item

peer-reviewed

Mark

Differential filamentation of Candida albicans and C. dubliniensis is governed by nutrient regulation of UME6 expression (2010)

SULLIVAN, DEREK

Trinity College Dublin

Journal article

peer-reviewed

Mark

Counter-regulation in the IKK family. (2011)

O'NEILL, LUKE

Trinity College Dublin

Journal article

peer-reviewed

Mark

Substrate-Promoted Formation of a Catalytically Competent Binuclear Center and Regulation of Reactivity in a Glycerophosphodiesterase from Enterobacter aerogenes (2008)

Hadler, Kieran S.; Tanifum, Eric A.; Hsu-Chen Yip, Sylvia; Mitic, Natasa; Guddat, Luke ...

Substrate-Promoted Formation of a Catalytically Competent Binuclear Center and Regulation of Reactivity in a Glycerophosphodiesterase from Enterobacter aerogenes (2008)

Hadler, Kieran S.; Tanifum, Eric A.; Hsu-Chen Yip, Sylvia; Mitic, Natasa; Guddat, Luke W.; Jackson, Colin J.; Gahan, Lawrence R.; Nguyen, Kelly; Carr, Paul D.; Ollis, David L.; Hengge, Alvan C.; Larrabee, James A.; Schenk, Gerhard

Abstract:

The glycerophosphodiesterase (GpdQ) from Enterobacter aerogenes is a promiscuous binuclear metallohydrolase that catalyzes the hydrolysis of mono-, di-, and triester substrates, including some organophosphate pesticides and products of the degradation of nerve agents. GpdQ has attracted recent attention as a promising enzymatic bioremediator. Here, we have investigated the catalytic mechanism of this versatile enzyme using a range of techniques. An improved crystal structure (1.9 Å resolution) illustrates the presence of (i) an extended hydrogen bond network in the active site, and (ii) two possible nucleophiles, i.e., water/hydroxide ligands, coordinated to one or both metal ions. While it is at present not possible to unambiguously distinguish between these two possibilities, a reaction mechanism is proposed whereby the terminally bound H2O/OH- acts as the nucleophile, activated via hydrogen bonding by the bridging water molecule. Furthermore, the presence of substrate promotes th...

Full-text link

http://eprints.maynoothuniversity.ie/3701/

Maynooth University

Journal article

peer-reviewed

Mark

Regulation of Surfactant Protein B Gene Expression in Bone Marrow-Derived Cells (2009)

Field-Corbett, Ciara; English, Karen; O'Dea, Shirley

Maynooth University

Journal article

peer-reviewed

Mark

Optimal metabolic regulation by temporal variation of enzyme activities: a control theoretic approach (2007)

Oyarzun, Diego; Ingalls, Brian; Kalamatianos, Dimitrios

Maynooth University

Journal article

peer-reviewed

Mark

Performance enhancement of wind turbine power regulation by switched linear control (1996)

Leith, Douglas J.; Leithead, W.E.

Maynooth University

Journal article

peer-reviewed

Mark

Sliding Doors Cost Measurement: The Net Economic Cost of Lax Regulation of the Irish Banking Sector (2012)

Connor, Gregory; O'Kelly, Brian

Maynooth University

Journal article

peer-reviewed

Mark

Role of KLF4 in regulation of myocardin induced SMC differentiation in human smooth muscle stem progenitor cells (hSMSPC) (2013)

Govindarajan, Kalaimathi

University College Cork

Doctoral thesis

non-peer-reviewed

Science Foundation Ireland

Mark

Transcriptional up-regulation of ULK1 by ATF4 contributes to cancer cell survival (2013)

MURRAY, JAMES

Trinity College Dublin

Journal article

peer-reviewed

Mark

Regulation of IL-1?-induced NF-?B by hydroxylases links key hypoxic and inflammatory signaling pathways. (2013)

FALLON, PADRAIC; HAMS, EMILY

Trinity College Dublin

Journal article

peer-reviewed

Mark

Regulation of IL-1β-induced NF-κB by hydroxylases links key hypoxic and inflammatory signaling pathways. (2013)

FALLON, PADRAIC

Trinity College Dublin

Journal article

peer-reviewed

Mark

Co-operative roles for DNA supercoiling and nucleoid-associated proteins in the regulation of bacterial transcription (2013)

DORMAN, CHARLES

Trinity College Dublin

Journal article

peer-reviewed

Mark

Charge profile analysis reveals that activation of pro-apoptotic regulators Bax and Bak relies on charge transfer mediated allosteric regulation. (2012)

Ionescu, Crina-Maria; Svobodová Vařeková, Radka; Prehn, Jochen HM; Huber, Heinrich J; K...

Royal College of Surgeons in Ireland

Journal article

peer-reviewed

Mark

Investigation into the role of La/SS-B in Interferon regulation and its relevance in health and human disease (2014)

Mahony, Rebecca G

Royal College of Surgeons in Ireland

Doctoral thesis

non-peer-reviewed

Mark

Regulating Everything: From Mega- to Meta-regulation (2012)

Scott, Colin

University College Dublin

Journal article

peer-reviewed

Irish Research Council for Humanities and Social Sciences

Mark

Licensing as a Tool of Regulation and Governance (2014)

Scott, Colin

University College Dublin

Journal article

peer-reviewed

Mark

An investigation into why companies delist from the main market on the Irish stock market to the Irish enterprise exchange and the impact of regulation (2009)

Harkin, Sarah

Connacht-Ulster Alliance

Master thesis (taught)

unknown

Mark

Financial Industry Ontologies for Risk and Regulation Data (FIORD): a position paper (2014)

Koumpis, Adamantios

NUI Galway

Conference item

peer-reviewed

Mark

Housing supply in Ireland since 1990: The role of costs and regulation (2015)

Lyons, Ronan C.

Trinity College Dublin

Journal article

unknown

Mark

Transcriptome Analysis of CD4+ T Cells in Coeliac Disease Reveals Imprint of BACH2 and IFN? Regulation. (2015)

MCMANUS, ROSS

Trinity College Dublin

Journal article

peer-reviewed

Mark

Platelet aggregation induced by Caco-2 cells: regulation by matrix metalloproteinase-2 and adenosine diphosphate (2006)

RADOMSKI, MAREK; SANTOS-MARTINEZ, MARIA; MEDINA MARTIN, CARLOS

Trinity College Dublin

Journal article

peer-reviewed

Mark

Transcription of Interleukin-8: How Altered Regulation Can Affect Cystic Fibrosis Lung Disease. (2015)

Jundi, Karim; Greene, Catherine M

Royal College of Surgeons in Ireland

Journal article

non-peer-reviewed

Displaying Results 76 - 100 of 3104 on page 4 of 125

NUI Galway

Dublin City University

University College Cork

Maynooth University

University College Dublin

University of Limerick

Trinity College Dublin

Mary Immaculate College

Dublin Institute of Technology

Lenus

Dundalk Institute of Technology

Marine Institute

Teagasc

All Ireland Public Health Repository

Royal College of Surgeons in Ireland

IUA

HEA

Legal Information | Copyright Information

built by Enovation Solutions