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Displaying Results 25051 - 25075 of 25142 on page 1003 of 1006
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New analytical tools and frameworks to understand dementia: What can a human-rights lens offer?
(2021)
Cahill, Suzanne; Sanchidrian, Monica
New analytical tools and frameworks to understand dementia: What can a human-rights lens offer?
(2021)
Cahill, Suzanne; Sanchidrian, Monica
Abstract:
The biomedical model has traditionally informed the dominant discourse on dementia and has significantly shaped practitioners?, policy makers? and researchers? responses. This model contextualises dementia as a progressive neuro-degenerative cognitive disorder and focuses on deficits and underlying pathology, often overlooking the fact that the person can and should be an active partner in the treatment process. Beginning in the late 1990s, the exclusive reliance on the bio-medical model has come under increasing scrutiny with a growing awareness that by recasting dementia in broader social and more humanitarian terms, much can be done to promote the individual's quality of life. Different frameworks and analytical tools have been forwarded to help us better understand dementia. These include personhood, citizenship, public health, disability and human rights. This review examines the merits of framing dementia as a disability, a citizenship concern and a human rights issue. It...
http://hdl.handle.net/2262/94466
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The interactions of apolipoprotein E and inflammation in human iPSC-derived astrocytes
(2020)
MC COMISH, SARAH FRANCES
The interactions of apolipoprotein E and inflammation in human iPSC-derived astrocytes
(2020)
MC COMISH, SARAH FRANCES
Abstract:
Alzheimer?s disease (AD) is a devastating neurodegenerative disease characterised histologically by the presence of extracellular plaques and intracellular neurofibrillary tangles, and clinically by memory loss, cognitive decline and personality changes. Much of the research investigating AD to date has focused on the familial early-onset form of AD which accounts for <5% of cases. Most cases are sporadic with late-onset, with certain genes presenting a high risk. Apolipoprotein E (APOE) genotype is one of the major genetic risk factors for late-onset AD. There are three major APOE isoforms (APOE2, APOE3and APOE4), each differing by a single amino acid residueat the protein leveland thus inferring different AD-risk. APOE2 contains cysteineat amino acid residues 112 and 158, APOE3contains a cysteine at residue 112 and arginine at residue 158, while APOE4 contains arginine at both residue sites.APOE3 is most common in the general population and ...
http://hdl.handle.net/2262/94468
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A Precision Medicine Approach to Dosing and Management of Continuous Renal Replacement Therapy for Acute Kidney Injury
(2020)
KELLY, YVELYNNE PATRICE
A Precision Medicine Approach to Dosing and Management of Continuous Renal Replacement Therapy for Acute Kidney Injury
(2020)
KELLY, YVELYNNE PATRICE
Abstract:
Background: Despite decades of research, the mainstay of treatment for severe acute kidney injury (AKI) in the critical care setting remains renal replacement therapy in the form of dialysis. Continuous renal replacement therapy (CRRT) poses the risk for unintended adverse events, which in general have been largely under-studied in critical care and nephrology; including depletion of phosphorus, amino acids, catecholamines and trace elements. CRRT also clears the circulation of medications, and dosing guidelines in general are not well established for CRRT. Aims: Higher intensity CRRT has been studied as a potential therapeutic advance for the treatment of severe AKI by increasing middle molecule clearance, enhancing acid-base buffering and potentially reducing pro-inflammatory cytokines in the setting of sepsis and shock; however it has never been shown to have a mortality benefit. I hypothesised that compared to standard intensity CRRT, higher intensity CRRT leads to greater haemo...
http://hdl.handle.net/2262/94467
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Lonely SARTs: Loneliness and sustained attention in the Irish Longitudinal Study on Ageing
(2020)
McHugh Power, Joanna; Hannigan, Caoimhe; Carney, Sile; Feeney, Joanne; Kenny, Rose Ann;...
Lonely SARTs: Loneliness and sustained attention in the Irish Longitudinal Study on Ageing
(2020)
McHugh Power, Joanna; Hannigan, Caoimhe; Carney, Sile; Feeney, Joanne; Kenny, Rose Ann; Kee, Frank; Lawlor, Brian A.
Abstract:
Based on biologically plausible mechanisms and previous research, it is possible to hypothesize a reciprocal association between sustained attention and loneliness. We investigated this association using a cross-lagged modeling approach. Using data from 6,239 participants aged over 50 in TILDA, a nationally representative study of aging, we used structural equation models to investigate potential cross-lagged associations between sustained attention and loneliness, measured at baseline and again after four years. Sustained attention at baseline had a small association with loneliness four years later, but loneliness at baseline was not associated with sustained attention at follow-up. Auto-regressive associations were strong for both loneliness over time and sustained attention over time. Sustained attention may account for a small proportion of the variance in loneliness over time among older adults, and may constitute a risk factor in the development of loneliness. Implications fo...
http://mural.maynoothuniversity.ie/13724/
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Developing elementary students' digital literacy through augmented reality creation: Insights From a longitudinal analysis of questionnaires, interviews, and projects
(2018)
Hsu, Hsiao-Ping; Wenting, Zou; Hughes, Joan E.
Developing elementary students' digital literacy through augmented reality creation: Insights From a longitudinal analysis of questionnaires, interviews, and projects
(2018)
Hsu, Hsiao-Ping; Wenting, Zou; Hughes, Joan E.
Abstract:
This mixed-method case study investigated digital literacy (DL) development among 32 elementary-level students who created multimodal, contextual, and interactive augmented reality (AR) artifacts in a 20-week after-school program in Northern Taiwan. The instructional design combined situated and spiral learning experiences with AR, implemented through a blended learning environment. Data sources included pre- and post-program digital learning student surveys, student and teacher interviews, classroom observations, and AR artifact assessments. Results indicated statistically significant increases with moderate effect sizes in five areas of students’ DL practices: information management; collaboration; communication and sharing; creation; and evaluation and problem-solving. Students did not increase DL in one area: ethics and responsibility. The situated and spiral learning-by-design approach offered increasingly complex AR creation projects in which students developed and transferred...
http://doras.dcu.ie/25277/
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Teaching topographic map skills and geomorphology concepts with Google Earth in a one-computer classroom
(2018)
Hsu, Hsiao-Ping; Tsai, Bor-Wen; Chen, Che-Ming
Teaching topographic map skills and geomorphology concepts with Google Earth in a one-computer classroom
(2018)
Hsu, Hsiao-Ping; Tsai, Bor-Wen; Chen, Che-Ming
Abstract:
Teaching high-school geomorphological concepts and topographic map reading entails many challenges. This research reports the applicability and effectiveness of Google Earth in teaching topographic map skills and geomorphological concepts, by a single teacher, in a one-computer classroom. Compared to learning via a conventional instructional method, students learning with Google Earth do not have different geomorphological concepts development because both settings enable students to learn with similar static representation. However, students learning with Google Earth improve topographic map skills significantly compared to the conventional instructional method. This is because of the 3D landscape visualization and prior knowledge connections available with Google Earth.
http://doras.dcu.ie/25278/
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Microbial metabolites as molecular mediators of host-microbe symbiosis in colorectal cancer
(2020)
Keane, Jonathan M.; Joyce, Susan A.; Gahan, Cormac G. M.; Hyland, Niall P.; Houston, Ai...
Microbial metabolites as molecular mediators of host-microbe symbiosis in colorectal cancer
(2020)
Keane, Jonathan M.; Joyce, Susan A.; Gahan, Cormac G. M.; Hyland, Niall P.; Houston, Aileen
Abstract:
The symbiosis between the gut microbiota and the host has been identified as an integral part of normal human physiology and physiological development. Research in germ-free or gnotobiotic animals has demonstrated the importance of this symbiosis in immune, vascular, hepatic, respiratory and metabolic systems. Disruption of the microbiota can also contribute to disease, and the microbiota has been implicated in numerous intestinal and extra-intestinal pathologies including colorectal cancer. Interactions between host and microbiota can occur either directly or indirectly, via microbial-derived metabolites. In this chapter, we focus on two major products of microbial metabolism, short-chain fatty acids and bile acids, and their role in colorectal cancer. Short-chain fatty acids are the products of microbial fermentation of complex carbohydrates and confer protection against cancer risk, while bile acids are compounds which are endogenous to the host, but undergo microbial modificatio...
http://hdl.handle.net/10468/10856
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Editorial: Innovative biologics and drugs to target renal inflammation
(2021)
Griffin, Matthew D.; Swaminathan, Sundararaman
Editorial: Innovative biologics and drugs to target renal inflammation
(2021)
Griffin, Matthew D.; Swaminathan, Sundararaman
Abstract:
[No abstract available]
SS is supported by the National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health under award number 1RO1DK103043. MG is supported by grants from the European Commission [Horizon 2020 Collaborative Health Project NEPHSTROM (grant number 634086) and FP7 Collaborative Health Project VISICORT (grant number 602470)] and from Science Foundation Ireland [CÚRAM Research Centre (grant number 13/RC/2073)] and by the European Regional Development Fund.
http://hdl.handle.net/10379/16398
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Mesenchymal stromal cell–based therapies for acute kidney injury: progress in the last decade
(2021)
Fazekas, Barbara; Griffin, Matthew D.
Mesenchymal stromal cell–based therapies for acute kidney injury: progress in the last decade
(2021)
Fazekas, Barbara; Griffin, Matthew D.
Abstract:
A little over 10 years ago, the therapeutic potential of mesenchymal stromal cells (MSCs) for the treatment of acute kidney injury (AKI) was becoming widely recognized. Since then, there has been further intensive study of this topic with a clear translational intent. Over the past decade, many more animal model studies have strengthened the evidence that systemically or locally delivered MSCs ameliorate renal injury in sterile and sepsis-associated AKI. Some of these preclinical studies have also provided a range of compelling new insights into the in vivo fate and mechanisms of action of MSCs in the setting of AKI and other inflammatory conditions. Coupled with increased knowledge of the functional roles of resident and infiltrating immune cell mediators in determining the severity and outcome of AKI, the progress made in the past decade would appear to have significantly strengthened the translational pathway for MSC-based therapies. In contrast, however, the extent of the clinic...
http://hdl.handle.net/10379/16399
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Alkoxyalkyl esters of nucleotide analogs inhibit polyomavirus DNA replication and large T antigen activities
(2021)
Onwubiko, Nichodemus O.; Diaz, Suraya; Krecmerova, Marcela; Nasheuer, Heinz-Peter
Alkoxyalkyl esters of nucleotide analogs inhibit polyomavirus DNA replication and large T antigen activities
(2021)
Onwubiko, Nichodemus O.; Diaz, Suraya; Krecmerova, Marcela; Nasheuer, Heinz-Peter
Abstract:
Polyomavirus-related infections are ubiqutious in immunocompromised individuals and in some cases are intractable and fatal. Due to lack of approved drugs to treat polyomavirus infections, cidofovir, a phosphonate nucleotide analog approved to treat cytomegalovirus infections has been repurposed as anti-polyomavirus agent. Cidofovir has been modified in various ways to improve its efficacies as broad-spectrum antiviral agent. However, the actual mechanisms and targets of cidofovir and its modified derivatives as anti-polyomavirus agents are still under research. Here, polyomavirus large tumor antigens (Tag) activities were identified as the viral target of cidofovir derivatives. The alkoxyalkyl-ester derivatives of cidofovir efficiently inhibit polyomavirus DNA replication in cell-free human extracts and a viral in vitro replication system only utilizing purified proteins. We present evidence that DNA helicase, and DNA binding activities of polyomavirus Tags are diminished in the pr...
http://hdl.handle.net/10379/16401
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Factors that potentially influence successful weight loss for adults with intellectual disabilities: A qualitative comparison
(2021)
Skelly, Laura J.; Smyth, Philomena P.; Donnelly, Mark P.; Leslie, Julian C.; Leader, Ge...
Factors that potentially influence successful weight loss for adults with intellectual disabilities: A qualitative comparison
(2021)
Skelly, Laura J.; Smyth, Philomena P.; Donnelly, Mark P.; Leslie, Julian C.; Leader, Geraldine; Simpson, Liz; McDowell, Claire
Abstract:
Background: People with intellectual disabilities are more at risk of obesity than the general population. Emerging literature indicates that multicomponent interventions are most effective, however, individual results are variable and little research exists as to why this is the case. Methods: Focus groups were conducted to explore lived experiences between two groups of adults with intellectual disabilities; an overweight group (n= 6) and a group identified as successful in losing weight (n= 6). Similarities and differences were explored across four domains. Transcripts were produced and analysed using Theoretical Thematic Analysis. Results: Similarities included service centre supports, basic food knowledge and issues restricting independence. The successful weight loss group had also internalised health messages, engaged with external reinforcement programmes, responded to positive feedback and demonstrated healthier dietary habits. Conclusion: Weight management interventions wo...
http://hdl.handle.net/10379/16404
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Mechanical and structural characterisation of the dural venous sinuses
(2020)
Walsh, Darragh R.; Lynch, James J; O'Connor, David T.; Newport, David; Mulvihill, ...
Mechanical and structural characterisation of the dural venous sinuses
(2020)
Walsh, Darragh R.; Lynch, James J; O'Connor, David T.; Newport, David; Mulvihill, John J E.
Abstract:
The dural venous sinuses play an integral role in draining venous blood from the cranial cavity. As a result of the sinuses anatomical location, they are of signifcant importance when evaluating the mechanopathology of traumatic brain injury (TBI). Despite the importance of the dural venous sinuses in normal neurophysiology, no mechanical analyses have been conducted on the tissues. In this study, we conduct mechanical and structural analysis on porcine dural venous sinus tissue to help elucidate the tissues’ function in healthy and diseased conditions. With longitudinal elastic moduli values ranging from 33 to 58 MPa, we demonstrate that the sinuses exhibit higher mechanical stifness than that of native dural tissue, which may be of interest to the feld of TBI modelling. Furthermore, by employing histological staining and a colour deconvolution protocol, we show that the sinuses have a collagen-dominant extracellular matrix, with collagen area fractions ranging from 84 to 94%, whic...
http://hdl.handle.net/10344/9562
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One-dimensional statistical parametric mapping identifies impaired orthostatic cerebrovascular and cardiovascular response in frailty index
(2020)
Romero-Ortuno, Roman; Knight, Silvin
One-dimensional statistical parametric mapping identifies impaired orthostatic cerebrovascular and cardiovascular response in frailty index
(2020)
Romero-Ortuno, Roman; Knight, Silvin
Abstract:
Background: Orthostasis is a potent physiological stressor which adapts with age. The age-related accumulation of health deficits in multiple physiological systems may impair the physiological response to orthostasis and lead to negative health outcomes such as falls, depression and cognitive decline. Research to date has focused on changes with orthostasis at prespecified intervals of time, without consideration for whole signal approaches. Methods: One-dimensional statistical parametric mapping (SPM 1d) identified regions in time of significant association between variables of interest using a general linear model. Frailty index operationalized accumulated health and social deficits using 32-items from an computer-assisted interview. This study examined the association of frailty index on blood pressure, heart rate and cerebral oxygenation during an orthostatic test in a sample of 2,742 adults aged 50 or older from The Irish Longitudinal Study on Ageing. Results: Frailty index ...
http://hdl.handle.net/2262/94529
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Well siblings' experiences of living with a child following a traumatic brain injury: a systematic review protocol
(2019)
Brenner, Maria
Well siblings' experiences of living with a child following a traumatic brain injury: a systematic review protocol
(2019)
Brenner, Maria
Abstract:
Background: The aim of this systematic review is to synthesize the available evidence identified through a systematic search on well siblings? experiences of living with a child following a traumatic brain injury (TBI). Brain injuries in children have been referred to as the ?silent epidemic? of current times. Brain injuries in children are also recognized as a global public health concern, with the impact on children, effects on family life, and caregiving markedly misunderstood and underestimated. It is widely recognized that a serious brain injury impacts on the whole family, both immediate and extended regardless of the age of the individual who experiences the brain injury. While some research refers to parental experiences of children with TBIs and caregivers experiences, there is a dearth of literature relating to the impact on well siblings and their perspectives. Well siblings? experiences regarding the impact of living with a child post-TBI are not well understood. In orde...
http://hdl.handle.net/2262/94535
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Differentiating editing, post-editing, and revision
(2020)
do Carmo, Félix; Moorkens, Joss
Differentiating editing, post-editing, and revision
(2020)
do Carmo, Félix; Moorkens, Joss
Abstract:
While several studies report translator resistance to post-editing, translators whose work has followed the evolution of translation technology may consider post-editing to be translation with just another input. The resistance narrative comes from translator perception and from an industry view of post-editing as a low-cost, low-skill revision task. This chapter challenges contemporary views of post-editing as revision, drawing from academic research, along with descriptions of practices and workflows from the industry, to argue that the addition of machine translation to translation workflows requires even more specialisation of translators. In arguing that post-editing should be viewed as a form of translation, we consider how translators are required to fulfil quality expectations and to perform higher order tasks than swapping words. The central focus of our analysis is the role played by editing, understood as four actions (deleting, inserting, moving and replacing), in distin...
http://doras.dcu.ie/25318/
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Development of Mode-matching Techniques to Efficiently Model Multi-mode Horns with Non-PEC Walls
(2019)
Brennan, Joseph; Gradziel, Marcin; Trappe, Neil
Development of Mode-matching Techniques to Efficiently Model Multi-mode Horns with Non-PEC Walls
(2019)
Brennan, Joseph; Gradziel, Marcin; Trappe, Neil
Abstract:
In the design and analysis of millimetre wave components imperfections of the guide wall material are frequently overlooked and PEC (Perfect Electric Conductor) behaviour is assumed to simplify the problem. These imperfections could be due to the large yet finite wall conductivity or the surface roughness associated with manufacturing processes. In reality, when non-PEC walls are considered, they have a non-negligible effect on mode attenuation and mode mixing, particularly at guide discontinuities An extension of the well-established Mode-Matching method to include non-PEC materials is investigated in this paper. Simply put, Mode-Matching is a method used to determine the scattering coefficients at guide discontinuities. Here the transverse fields on both sides of the step are “matched” such that we have conservation of complex power for incident modes. The additional boundary conditions imposed by the non-PEC walls are considered as perturbations to the PEC solutions. In uniform g...
http://mural.maynoothuniversity.ie/13784/
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Quantifying used electrical and electronic equipment exported from ireland to west africa in roll-on roll-off vehicles
(2021)
McMahon, Kathleen; Uchendu, Chidinma; Fitzpatrick, Colin
Quantifying used electrical and electronic equipment exported from ireland to west africa in roll-on roll-off vehicles
(2021)
McMahon, Kathleen; Uchendu, Chidinma; Fitzpatrick, Colin
Abstract:
The investigation on the transboundary shipment of used and waste electrical and electronic equipment from developed countries is a well-studied subject with regard to the environmental and health impacts in the destination countries when it reaches end-of-life. Prior research has ranked Ireland the 8th highest source of used electrical and electronic equipment (UEEE) into Nigeria, with roll-on roll-off (RoRo) vehicles as the largest carrier (Odeyingbo 2017). This study presents the first comprehensive port of origin estimation of UEEE export shipments from Ireland in RoRo vehicles. This was obtained by using a ‘person in the port’ involving vehicle and enforcement document inspections at the Ringaskiddy port in Cork, Ireland. By scaling sampling data to annual shipment figures, it was estimated that 17,319 kg of UEEE are currently exported from Ireland annually and that around 1 in 5 vehicles exported contain UEEE. Additionally, the type of UEEE and frequency of shipments show cert...
http://hdl.handle.net/10344/9565
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Advanced paramedics in general practice in Ireland – an exploratory study
(2020)
Feerick, Fintan
Advanced paramedics in general practice in Ireland – an exploratory study
(2020)
Feerick, Fintan
Abstract:
Introduction: Healthcare policy in Ireland is in a state of transition due to an increased aging population with chronic disease and co-morbidities, demands for services will rise. To help reduce pressures on the acute hospital setting, more patients and services are being directed towards general practice and primary care services. As Irelands population increases and chronic disease becomes more prevalent, demand on limited general practice services will increase. Current and future predictions suggest that there are insufficient numbers of existing General Practitioners (GPs) available to meet this increased demand. Globally, during times of healthcare workforce shortages, various health systems have adopted “task shifting” models of healthcare delivery, where certain roles or tasks are undertaken by alternative nonmedical personnel with less education and training, in order to alleviate some of the pressures on limited medical personnel. Evidence suggests that there is an appeti...
http://hdl.handle.net/10344/9568
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A dancer in the mirror: body identity and body motion in Danza Española
(2020)
Mateos Morante, Rebeca Tania
A dancer in the mirror: body identity and body motion in Danza Española
(2020)
Mateos Morante, Rebeca Tania
Abstract:
This thesis is grounded in ethnochoreology and incorporates a psychoanalytical understanding of body identity and a phenomenological understanding of body motion. What is investigated is a professional Danza Española dancer’s relationship with the reflected image inside the mirror to meet with the demands of this formalised dance genre. Accordingly, my primary research question is: Can the mirror ultimately sustain fundamental aspects of a dancer’s body identity and body motion wherein the codification of dance practice is based on a primarily visual above proprioceptive sense of corporeal awareness and agency? Initially, I position the Danza Española genre within a broader historical reading of the sociocultural interdependence that developed between both the artefact of inquiry (the mirror) and subject of inquiry (European-originated formalised dance practice) climaxing in what I term the primacy of gaze during the height of the Baroque period. Subsequently, upon tracing the elabo...
http://hdl.handle.net/10344/9570
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Spectres of Goffman: Impression management in the Irish welfare space
(2020)
Whelan, Joe
Spectres of Goffman: Impression management in the Irish welfare space
(2020)
Whelan, Joe
Abstract:
The Goffmanian thesis of stigma occurring as an aspect of “spoiled identity” has arguably provided the dominant theoretical understanding of social stigma over the past half century. Yet, there have also been strong critiques of Goffman’s thesis of stigma which range from concerns with the micro-personal nature of his work to question marks over the corpus of materials used by Goffman when originally theorizing stigma. Recent scholarly contributions have theorized a more structural understanding of the role and function of stigma and this, in turn, has arguably forced the question of whether or not Goffman’s thesis of stigma has now become redundant in terms of its application in the social sciences. This paper intends to explore this question by offering a juxtaposition of the theoretical and the empirical. To meet this task, the paper first engages in a theoretical discussion of the Goffmanian thesis of social stigma. Crucially, however, original research, conducted in Ireland, is...
http://hdl.handle.net/10468/10873
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Dating with a diagnosis: The lived experience of people with multiple sclerosis
(2021)
Tabassum, Kinza; Fox, Jackie; Fuller, Sara; Hynes, Sinéad
Dating with a diagnosis: The lived experience of people with multiple sclerosis
(2021)
Tabassum, Kinza; Fox, Jackie; Fuller, Sara; Hynes, Sinéad
Abstract:
Background: With an average age of onset of about 20-40 years, MS usually manifests during early adulthood, which is considered to be a critical period for the development and maintenance of relationships particularly dating and romantic relationships. People with MS can experience sexual dysfunction, fatigue, pain, reduced mood and bladder/bowel dysfunction. These difficulties can affect a person s ability to participate in many meaningful activities, including those that affect relationships dating, preparing meals, engaging in sexual intercourse and others. Research in the area has explored the experiences of people with MS in long-term relationships or in marriage. However, an increasing number of people are not in long-term relationships in their 20 s, 30 s and beyond. It is known that dating or entering romantic relationships has been shown to be difficult for those with physical disabilities who face stigma, negative societal attitudes and the fear of requiring care from ...
http://hdl.handle.net/10379/16416
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Coupling of autism genes to tissue-wide expression and dysfunction of synapse, calcium signalling and transcriptional regulation.
(2021)
Reilly, Jamie; Gallagher, Louise; Leader, Geraldine; Shen, Sanbing
Coupling of autism genes to tissue-wide expression and dysfunction of synapse, calcium signalling and transcriptional regulation.
(2021)
Reilly, Jamie; Gallagher, Louise; Leader, Geraldine; Shen, Sanbing
Abstract:
Autism Spectrum Disorder (ASD) is a heterogeneous disorder that is often accompanied with many co-morbidities. Recent genetic studies have identified various pathways from hundreds of candidate risk genes with varying levels of association to ASD. However, it is unknown which pathways are specific to the core symptoms or which are shared by the co-morbidities. We hypothesised that critical ASD candidates should appear widely across different scoring systems, and that comorbidity pathways should be constituted by genes expressed in the relevant tissues. We analysed the Simons Foundation for Autism Research Initiative (SFARI) database and four independently published scoring systems and identified 292 overlapping genes. We examined their mRNA expression using the Genotype-Tissue Expression (GTEx) database and validated protein expression levels using the human protein atlas (HPA) dataset. This led to clustering of the overlapping ASD genes into 2 groups; one with 91 genes primarily ex...
http://hdl.handle.net/10379/16417
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The aesthetics of challenge: Mario Perniola and Dandyism
(2021)
Bianchi, Enea
The aesthetics of challenge: Mario Perniola and Dandyism
(2021)
Bianchi, Enea
Abstract:
This thesis compares the work of the Italian philosopher and writer Mario Perniola and the phenomenon of dandyism. Specifically, it focuses on Perniola’s aesthetic and philosophical thought in order to develop and explore its affinity with three exemplar dandies, namely George Bryan Brummell (1778-1840), Charles Baudelaire (1821-1867), and Oscar Wilde (1854-1900). The thesis’s aim is to show that Perniola’s philosophy can be considered a “dandy” philosophy. In fact, as I will argue over the course of this research, his theoretical perspective finds in the dandies’ lifestyles a significant realisation, that is, his thought can be considered as an embodiment of the dandies’ key behaviours and attitudes. Specifically, my work will provide an original contribution on three main points. First, although Perniola’s writings have been translated into over fifteen languages, and in spite of a copious number of reviews, articles and texts published on his work, no scholar has yet highlighted ...
http://hdl.handle.net/10379/16414
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Improving robustness and accuracy of predicted daily methane emissions of dairy cows using milk mid‐infrared spectra
(2021)
Vanlierde, Amélie; Dehareng, Frédéric; Gengler, Nicolas; Froidmont, Eric; McParland, Si...
Improving robustness and accuracy of predicted daily methane emissions of dairy cows using milk mid‐infrared spectra
(2021)
Vanlierde, Amélie; Dehareng, Frédéric; Gengler, Nicolas; Froidmont, Eric; McParland, Sinead; Kreuzer, Michael; Bell, Matthew; Lund, Peter; Martin, Cécile; Kuhla, Björn; Soyeurt, Hélène
Abstract:
BACKGROUND A robust proxy for estimating methane (CH4) emissions of individual dairy cows would be valuable especially for selective breeding. This study aimed to improve the robustness and accuracy of prediction models that estimate daily CH4 emissions from milk Fourier transform mid‐infrared (FT‐MIR) spectra by (i) increasing the reference dataset and (ii) adjusting for routinely recorded phenotypic information. Prediction equations for CH4 were developed using a combined dataset including daily CH4 measurements (n = 1089; g d−1) collected using the SF6 tracer technique (n = 513) and measurements using respiration chambers (RC, n = 576). Furthermore, in addition to the milk FT‐MIR spectra, the variables of milk yield (MY) on the test day, parity (P) and breed (B) of cows were included in the regression analysis as explanatory variables. RESULTS Models developed based on a combined RC and SF6 dataset predicted the expected pattern in CH4 values (in g d−1) during a lactation cycle,...
http://hdl.handle.net/11019/2360
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A review of executive functions in Autism Spectrum Disorder and Attention Deficit Hyperactivity Disorder
(2021)
Berenguer, Carmen; Roselló, Belén; Leader, Geraldine
A review of executive functions in Autism Spectrum Disorder and Attention Deficit Hyperactivity Disorder
(2021)
Berenguer, Carmen; Roselló, Belén; Leader, Geraldine
Abstract:
Autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) are two of the most common childhood-onset neurodevelopmental disorders. Literature has shown different patterns of deficits in executive functioning in children with ASD and ADHD. To date few studies have examined executive functions in both ASD and ADHD and with mixed results. The current study provides the first systematic review to explore distinct executive function components (attention problems, response inhibition, working memory, planning and flexibility) that underlie the specific deficits seen in children and adolescents with both ASD and ADHD disorders. Findings provide evidence for executive dysfunctions across different key components such as attention, response inhibition and verbal working memory in children and adolescents with ASD and comorbid ADHD clinical symptoms. This research explores the neurocognitive profile of the comorbid condition, which is also critical for designing appr...
http://hdl.handle.net/10379/16425
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